Universitat de Barcelona
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Política d’accés obert a la UB
Publicacions en accés obert derivades de l'activitat investigadora del professorat de la Universitat de Barcelona.
Heart failure (HF) is becoming increasingly common, especially in older females, and displays marked sex-related differences in pathophysiology, treatment, and outcomes. Submaximal exercise capacity (SEC), frequently ...
Megalencephalic leukoencephalopathy with subcortical cyst (MLC) is a rare leukodystrophy primarily caused by mutations in two genes: MLC1, encoding a membrane protein of unknown function, and GlialCAM, a cell adhesion ...
BACKGROUND The phase 3 KEYNOTE-671 study (NCT03425643) demonstrated significantly improved event-free survival (EFS) and overall survival with neoadjuvant pembrolizumab plus chemotherapy followed by surgery and adjuvant ...
Background and Objectives: The anesthetic nerve block test is a surgical technique that can assist in the differential diagnosis of forefoot pain. The MTP joint, enclosed by its capsule, may act as a sealed cavity with ...
CLC channels and transporters have large C-terminal regions which contain two cystathionine β-synthetase (CBS) domains. It has been hypothesized that conformational changes in these domains upon nucleotide binding modulate ...
Background. Mortality rates from Staphylococcus aureus bacteremia are high and have only modestly improved in recent decades. We compared the efficacies of a beta-lactam in combination with daptomycin (BL/D-C) and beta-lactam ...
Vaccinia virus (VACV) is widely used as a vaccine and oncolytic vector due to its safety profile and its capacity to accommodate exogenous DNA. However, its compact genome offers limited for transgene insertion without ...
The hypothalamus, a central regulator of hunger and metabolism, contains subnuclei responsive to peripheral signals such as leptin and ghrelin, which may be altered in anorexia nervosa (AN) and obesity (OB). This exploratory ...
Nurses’ teaching skills in the clinical setting are crucial to ensuring that students receive high-quality training. Despite the growing importance of competency frameworks, there is little research on the relationship ...
Background: Colorectal cancer (CRC) remains a major global health concern, partly due to resistance to therapy and the lack of new effective treatments for advanced disease. The combination of 5-Fluorouracil (5FU, a ...
Introduction: The XVII edition of the post-European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting was held on 4-5 October 2024 in Madrid. This event was attended by Spanish neurologists ...
Introduction: The XVII edition of the post-European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting was held on 4-5 October 2024 in Madrid. This event was attended by Spanish neurologists ...
Colorectal cancer (CRC) frequently develops aggressive metastatic disease, yet the cellular features that enable dissemination remain poorly defined. IKK alpha, a kinase traditionally linked to stress and inflammatory ...
Protocolo para realizar un estudio longitudinal prospectivo y unicéntrico sobre el análisis de la incidencia y probabilidad de regresión y/o progresión de las lesiones de alto grado durante el cribado de cáncer anal de una ...
Introduction: hybrid rooms (HR) provide advanced imaging capabilities within an optimal open surgical environment. The technology associated with hybrid rooms facilitates endovascular navigation and enhances technical ...
Rationale: Tracheobronchial stents are used to treat central airway obstruction but frequently develop bacterial colonization that can lead to infection.Objectives: To identify the microorganisms responsible for stent ...
Objectives: This study aimed to evaluate the cytotoxic effects of Ti6Al4V particles and implantoplasty (IP)-treated surfaces on human fibroblasts and osteoblasts, and to investigate the influence of these particles on ...
Introduction Accurate assessment of disease activity in SLE is crucial but challenging due to its varied clinical manifestations and severity. Current tools like the SLE Disease Activity Index (SLEDAI) have limitations, ...
Primary humoral immunodeficiencies are a heterogeneous group of disorders defined by quantitative and/or functional defects in one or more immunoglobulin classes, often with associated cellular immune abnormalities. Their ...
Background: Major Depressive Disorder (MDD) has been associated with disruptions in circadian rhythms and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. Circadian rhythms are regulated by clock genes, ...
