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IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer: Recent submissions

Now showing items 621-640 of 3164

    Management of cytomegalovirus in adult solid organ transplant patients: GESITRA-IC-SEIMC, CIBERINFEC, and SET recommendations update 

    Ruiz Arabi, Elisa; Torre Cisneros, Julian; Aguilera, Victoria; Alonso, Rodrigo; Berenguer, Marina; Bestard Matamoros, Oriol; Bodro, Marta; Cantisán, Sara; Carratalà, Jordi; Castón, Juan José; Cordero, Elisa; Facundo, Carme; Fariñas, María Carmen; Fernández Alonso, Mirian; Fernández Ruiz, Mario; Fortún, Jesús; García Cosío, María Dolores; Herrera, Sabina; Iturbe Fernández, David; Len, Oscar; López Medrano, Francisco; López Oliva, María Ovidia; Los-Arcos, Ibai; Marcos, María Ángeles; Martín Dávila, Pilar; Monforte, Víctor; Muñoz, Patricia; Navarro, David; Páez Vega, Aurora; Pérez, Ana Belén; Redondo, Natalia; Álvarez, R. Rodríguez; Rodríguez Benot, Alberto; Rodríguez Goncer, Isabel; San Juan, Rafael; Sánchez Céspedes, Javier; Valerio, Maricela; Vaquero, José Manuel; Viasus, Diego; Vidal, Elisa; Aguado, José María (Publication date: 2025-01-10)

    Cytomegalovirus (CMV) infection remains a significant challenge in solid organ transplantation (SOT). The last international consensus guidelines on the management of CMV in SOT were published in 2018, highlighting the ...

    Spanish validation of the Barcelona TEMPS-A questionnaire in patients with bipolar disorder and general population 

    Jiménez Martínez, Ester; Bonnín Roig, Caterina del Mar; Solé Cabezuelo, Brisa; Sánchez-Moreno, José; Reinares, María; Torrent Font, Carla; Torres, Imma; Salagre Muñoz, Estela; Varo, Cristina; Ruíz, Victoria; Giménez Palomo, Anna; Benabarre, Antonio; Gutiérrez-Rojas, Luis; Cervilla, Jorge; Sáiz Martínez, Pilar Alejandra; García Portilla, María Paz; Bobes García, Julio; Amann, Benedikt L.; Martínez-Arán, Anabel, 1971-; Vieta i Pascual, Eduard, 1963- (Publication date: 2026-01-12)

    Background: The Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego (TEMPS-A) is a self-administered questionnaire intended to assess five affective temperaments: depressive, cyclothymic, hy-perthymic, irritable ...

    Delusional beliefs in adolescents with anorexia nervosa, obsessive-compulsive disorder, or first-episode psychosis: A comparative study 

    Camprodon Boadas, Patricia; Serna Gómez, Elena de la; Plana, Maria Teresa; Flamarique, Itziar; Lázaro García, Luisa; Borràs, Roger; Baeza, Inmaculada, 1970-; Tasa Vinyals, Elisabet; Sugranyes, Gisela; Ortiz, Ana Encarnación; Castro Fornieles, Josefina (Publication date: 2024-01-24)

    Delusional thinking is a key symptom of first-episode psychosis (FEP), but it has also been studied in obsessivecompulsive disorder (OCD) and anorexia nervosa (AN). This study aimed to analyze the psychometric properties ...

    Clinical impact of recurrently mutated genes on lymphoma diagnostics 

    Rosenquist, Richard; Rosenwald, Andreas; Du, Ming-Qing; Gaidano, Gianluca; Groenen, Patricia; Wotherspoon, Andrew; Ghia, Paolo; Gaulard, Philippe; Campo Güerri, Elias; Stamatopoulos, Kostas (Publication date: 2017-09-08)

    Similar to the inherent clinical heterogeneity of most, if not all, lymphoma entities, the genetic landscape of these tumors is markedly complex in the majority of cases, with a rapidly growing list of recurrently mutated ...

    Coronary Microvascular Angina: A State-of-the-Art Review 

    Spione, Francesco; Arévalos, Victor; Gabani, Rami; Sabaté Tenas, Manuel; Brugaletta, Salvatore (Publication date: 2023-07-26)

    Up to 60-70% of patients, undergoing invasive coronary angiography due to angina and demonstrable myocardial ischemia with provocative tests, do not have any obstructive coronary disease. Coronary microvascular angina due ...

    Correlative Biomarker Analysis of Intrinsic Subtypes and Efficacy Across the MONALEESA Phase III Studies 

    Prat Aparicio, Aleix; Chaudhury, Anwesha; Solovieff, Nadia; Paré Brunet, Laia; Martínez Pérez, Debora; Chic Ruche, Nuria; Martínez Sáez, Olga; Brasó Maristany, Fara; Lteif, Agnes; Taran, Tetiana; Babbar, Naveen; Su, Fei (Publication date: 2024-08-26)

    PURPOSE: The prognostic and predictive value of intrinsic subtypes in hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer treated with endocrine therapy and ribociclib (RIB) ...

    Increased PVR Expression on Bone Marrow Macrophages May Promote Resistance to TIGIT Blockade in Multiple Myeloma.  

    Lozano Garcia, Ester; Mena, Mari-Pau; Garrabou Tornos, Glòria; Cardús, Oriol; Díaz Sánchez, Tania; Moreno, David F.; Mañé Pujol, Joan; Oliver-Caldés, Aina; Battram, Anthony M.; Tovar, Natalia; Cibeira López, M. Teresa; Rodríguez-Lobato, Luis-Gerardo; Bladé, J. (Joan); Fernández de Larrea Rodríguez, Carlos José; Rosiñol Dachs, Laura (Publication date: 2024-11-25)

    Purpose:TIGIT blockade in our ex vivo model of bone marrow (BM) reduced the number of malignant plasma cells (PC) in only half of patients with multiple myeloma. Here, we wanted to investigate whether increased expression ...

    Geolocation with respect to personal privacy for the Allergy Diary app - A MASK study 

    Antó i Boqué, Josep Maria; Mullol i Miret, Joaquim; Valero, Antonio; Rodó López, Xavier; Rizzo, J. A.; MASK study group (Publication date: 2020-03-03)

    Background: Collecting data on the localization of users is a key issue for the MASK (Mobile Airways Sentinel networK: the Allergy Diary) App. Data anonymization is a method of sanitization for privacy. The European ...

    RAD51 is a druggable target that sustains replication fork progression upon DNA replication stress. 

    Feu i Coll, Sònia; Unzueta Payeras, Fernando; Ercilla Eguiarte, Amaia; Pérez-Venteo, Alejandro; Jaumot i Pijoan, Montserrat; Agell i Jané, Neus (Publication date: 2022-10-24)

    Solving the problems that replication forks encounter when synthesizing DNA is essential to prevent genomic instability. Besides their role in DNA repair in the G2 phase, several homologous recombination proteins, specifically ...

    An overview of treatment options for patients with relapsed/refractory multiple myeloma and renal impairment 

    Dimopoulos, Meletios A.; Mikhael, Joseph; Terpos, Evangelos; Leleu, Xavier; Moreau, Philippe; Bladé, J. (Joan); Kim, Jin Seok; Stockerl Goldstein, Keith; Richardson, Paul G. (Publication date: 2024-01-30)

    Renal impairment (RI) is a relatively common complication of multiple myeloma, which increases in frequency as disease becomes more advanced and recovery of renal function becomes less likely as patients progress through ...

    Systemic and local inflammatory response in women with preterm prelabor rupture of membranes 

    Cobo Cobo, María Teresa; Jacobsson, Bo; Kacerovsky, Marian; Hougaard, David M.; Skogstrand, Kristin; Gratacós Solsona, Eduard; Palacio, Montse (Publication date: 2018-03-20)

    Objective:To evaluate the inflammatory pattern in maternal circulation, amniotic cavity, cervix and vagina from women with preterm prelabor rupture of membranes (PPROM) considering the occurrence of microbial invasion of ...

    Increased power by harmonizing structural MRI site differences with the comBat batch adjustment method in ENIGMA 

    Radua, Joaquim; Vieta i Pascual, Eduard, 1963-; Shinohara, Russell; Kochunov, Peter; Quidé, Yann; Green, Melissa J.; Weickert, Cynthia S.; Weickert, Thomas; Bruggemann, Jason; Kircher, Tilo; Nenadic, Igor; Cairns, Murray J.; Seal, Marc; Schall, Ulrich; Henskens, Frans; Fullerton, Janice M.; Mowry, Bryan; Pantelis, Christos; Lenroot, Rhoshel; Cropley, Vanessa; Loughland, Carmel; Scott, Rodney J.; Wolf, Daniel; Satterthwaite, Theodore D.; Tan, Yunlong; Sim, Kang; Piras, Fabrizio; Spalletta, Gianfranco; Banaj, Nerisa; Pomarol-Clotet, Edith; Solanes, Aleix; Albajes Eizagirre, Anton; Canales Rodríguez, Erick Jorge; Sarró, Salvador; Di Giorgio, Annabella; Bertolino, Alessandro; Stäblein, Michael; Oertel, Viola; Knöchel, Christian; Borgwardt, Stefan; du Plessis, Stefan; Yun, Je-Yeon; Kwon, Jun Soo; Dannlowski, Udo; Hahn, Tim; Grotegerd, Dominik; Alloza, Clara; Arango López, Celso; Janssen, Joost; Díaz Caneja, Covadonga M.; Jiang, Wenhao; Calhoun, Vince; Ehrlich, Stefan; Yang, Kun; Cascella, Nicola G.; Takayanagi, Yoichiro; Sawa, Akira; Tomyshev, Alexander; Lebedeva, Irina; Kaleda, Vasily; Kirschner, Matthias; Hoschl, Cyril; Tomecek, David; Skoch, Antonin; van Amelsvoort, Therese; Bakker, Geor; James, Anthony; Preda, Adrian; Weideman, Andrea; Stein, Dan J.; Howells, Fleur; Uhlmann, Anne; Temmingh, Henk; López Jaramillo, Carlos; Díaz Zuluaga, Ana M.; Fortea, Laura; Martínez Heras, Eloy; Solana Díaz, Elisabeth; Llufriu Duran, Sara; ENIGMA Consortium; ENIGMA Consortium collaborators (Publication date: 2025-03-24)

    A common limitation of neuroimaging studies is their small sample sizes. To overcome this hurdle, the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium combines neuroimaging data from many institutions ...

    Low transmission of SARS-CoV-2 derived from children in family clusters: An observational study of family households in the Barcelona Metropolitan Area, Spain 

    Melé Casas, Maria; Launes Montaña, Cristian; Fernández de Sevilla Estrach, Mariona; Hernández García, María; Pons Tomàs, Gemma; Bassat Orellana, Quique; Fumadó, Victoria; Fortuny Guasch, Claudia; Garcia Miquel, Aleix; Bonet Carné, Elisenda; Prats, Clara; Ajanovic, Sara; Cubells, Marta; Claverol, Joana; Penela Sánchez, Daniel; Jou, Cristina; Arias, Sara; Balanza Lombardia, Núria; Baro, Bàrbara; Millat Martínez, Pere; Alonso Muñoz, Sergio; Álvarez Lacalle, Enrique; Català, Martí; Cuadras, Daniel; Muñoz-Almagro, Carmen; Gratacós Solsona, Eduard; Jordán García, Iolanda; García García, Juan José (Publication date: 2024-04-08)

    Background: Family clusters offer a good opportunity to study viral transmission in a stable setting. We aimed to analyze the specific role of children in transmission of SARS-CoV-2 within households. Methods: A prospective, ...

    Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells 

    Meneses Salas, Elsa; García Melero, Ana; Kanerva, Kristiina; Blanco Muñoz, Patricia; Morales Paytuvi, Frederic; Bonjoch, Júlia; Casas Brugulat, Josefina; Egert, Antonia; Beevi, Syed S.; Jose, Jaimy; Llorente Cortés, Vicenta; Rye, Kerry-Anne; Heeren, Joerg; Lu, Albert; Pol i Sorolla, Albert; Tebar Ramon, Francesc; Ikonen, Elina; Grewal, Thomas; Enrich Bastús, Carles; Rentero Alfonso, Carles (Publication date: 2020-01-24)

    Cholesterol accumulation in late endosomes is a prevailing phenotype of Niemann-Pick type C1 (NPC1) mutant cells. Likewise, annexin A6 (AnxA6) overexpression induces a phenotype reminiscent of NPC1 mutant cells. Here, we ...

    Effects of Albumin Treatment on Systemic and Portal Hemodynamics and Systemic Inflammation in Patients With Decompensated Cirrhosis 

    Fernández Gómez, Javier; Clària i Enrich, Joan; Amorós, Àlex; Aguilar, Ferran; Castro, Miriam; Casulleras, Mireia; Acevedo, Juan; Duran Güell, Marta; Nuñez, Laura; Costa, Montserrat; Torres Hurtado, Mirea; Horrillo, Raquel; Ruiz-del-Árbol, Luis; Villanueva Sánchez, Càndid; Prado, Verónica; Arteaga López, Mireya; Trebicka, Jonel; Angeli, Paolo; Merli, Manuela; Alessandria, Carlo; Aagaard, Niels Kristian; Soriano Pastor, Germán; Durand, François; Gerbes, Alexander L.; Gustot, Thierry; Welzel, Tania Mara; Salerno, Francesco; Bañares, Rafael; Vargas, Víctor; Albillos, Agustín; Silva, Aníbal; Morales Ruiz, Manuel; Pavesi, Marco; Jalan, Rajiv; Bernardi, Mauro; Moreau, Richard; Páez, Antonio; Arroyo, Vicente (Publication date: 2020-04-27)

    BACKGROUND & AIMS: We investigated the effect of albumin treatment (20% solution) on hypoalbuminemia, cardiocirculatory dysfunction, portal hypertension, and systemic inflammation in patients with decompensated cirrhosis ...

    MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence 

    Morais‑Almeida, M.; Antó i Boqué, Josep Maria; Mullol i Miret, Joaquim; Valero, Antonio; MASK study group (Publication date: 2020-03-03)

    Health, such as apps running on consumer smart devices is becoming increasingly popular and has the potential to profoundly affect healthcare and health outcomes. However, it may be disruptive and results achieved are not ...

    Susac Syndrome: Description of a Single-Centre Case Series 

    Beça, Sara; Elera Fitzcarrald, Claudia; Saiz, Albert; Llufriu Duran, Sara; Cid, María C.; Sánchez Dalmau, Bernardo; Adán Civera, Alfredo; Espinosa Garriga, Gerard (Publication date: 2023-05-12)

    This study describes the clinical characteristics, diagnostic results, treatment regimens, and clinical course of a cohort of patients with Susac syndrome (SS). It is a retrospective observational study of all patients ...

    Exosomal microRNAs isolated from plasma of mesenteric veins linked to liver metastases in resected patients with colon cancer 

    Monzó Planella, Mariano; Santasusagna, Sandra; Moreno, Isabel; Martinez, Francisco; Hernández, Raquel; Muñoz, Carmen; Castellano, Joan Josep; Moreno, Josep; Navarro Ponz, Alfons (Publication date: 2018-03-22)

    Before reaching a peripheral vein (PV), miRNAs released by the tumor are diluted and dispersed throughout the body or even retained in a specific organ. We hypothesized that blood drawn from the tumor-draining vein could ...

    Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung 

    Lugo, Roberto; Gabasa Ferràndez, Marta; Andriani, Francesca; Puig, Marta; Facchinetti, Federica; Ramírez Ruz, J. (José); Gómez Caro, Abel; Pastorino, Ugo; Fuster Orellana, Gemma; Almendros López, Isaac; Gascón, Pere; Dávalos, Albert; Reguart, Noemí; Roz, Luca; Alcaraz Casademunt, Jordi (Publication date: 2017-01-03)

    Senescence in cancer cells acts as a tumor suppressor, whereas in fibroblasts enhances tumor growth. Senescence has been reported in tumor associated fibroblasts (TAFs) from a growing list of cancer subtypes. However, the ...

    Plasma calprotectin as a biomarker of ultrasound synovitis in rheumatoid arthritis patients receiving IL-6 antagonists or JAK inhibitors 

    Frade Sosa, Beatriz; Ponce, Andrés; Inciarte Mundo, José; Morla, Rosa; Ruíz Esquide, Virginia; Macías Muñoz, Laura; Azuaga, Ana Belén; Ramírez, Julio; Cañete Crespillo, Juan D.; Yagüe, Jordi; Auge, Josep Maria; Gómez Puerta, José A.; Sanmartí Sala, Raimon (Publication date: 2024-01-29)

    To analyse the accuracy of plasma calprotectin in patients with rheumatoid arthritis (RA) receiving monoclonal antibodies against IL-6 receptors (anti-rIL-6) or JAK inhibitors (JAKis) in detecting ultrasound (US) synovitis ...