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IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer: Envíos recientes

Mostrando ítems 601-620 de 3164

    Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a multinational point prevalence study of hospitalised patients 

    Restrepo, Marcos I.; Babu, Bettina L.; Reyes, Luis F.; Chalmers, James D.; Soni, Nilam J.; Sibila Vidal, Oriol; Faverio, Paola; Cillóniz, Catia; Rodriguez-Cintron, William; Aliberti, Stefano; GLIMP Study Group (Fecha de publicación: 2019-07-09)

    Pseudomonas aeruginosa is a challenging bacterium to treat due to its intrinsic antibiotic resistance to the most frequently used antibiotics in patients with community-acquired pneumonia (CAP). Data about the global burden ...

    Paraneoplastic cerebellar ataxia and antibodies to metabotropic glutamate receptor 2 

    Ruiz García, Raquel; Martinez Hernandez, Eugenia; Joubert, Bastien; Petit Pedrol, Mar; Pajarón Boix, Elena; Fernández, Verónica; Salais, Lidia; Pozo, María del; Armangué, Thaís; Sabater Baudet, Lidia; Dalmau Obrador, Josep; Graus, Francesc (Fecha de publicación: 2022-03-09)

    To report the presence of a new neuronal surface antibody against the metabotropic glutamate receptor 2 antibody (mGluR2-Ab) in 2 patients with paraneoplastic cerebellar ataxia.mGluR2-Abs were initially characterized by ...

    Heart failure during the COVID-19 pandemic: clinical, diagnostic, management, and organizational dilemmas 

    Palazzuoli, Alberto; Metra, Marco; Collins, Sean P.; Adamo, Marianna; Ambrosy, Andrew P.; Antohi, Laura E.; Ben Gal, Tuvia; Farmakis, Dimitrios; Gustafsson, Finn; Hill, Loreena; Lopatin, Yuri; Tramonte, Francesco; Lyon, Alexander; Masip, Josep (Masip i Utset); Miró i Andreu, Òscar; Moura, Brenda; Mullens, Wilfried; Radu, Razvan I.; Abdelhamid, Magdy; Anker, Stefan; Chioncel, Ovidiu (Fecha de publicación: 2023-06-26)

    The coronavirus 2019 (COVID-19) infection pandemic has affected the care of patients with heart failure (HF). Several consensus documents describe the appropriate diagnostic algorithm and treatment approach for patients ...

    Academic Productivity of Young People With Allergic Rhinitis: A MASK-air Study 

    Viera, Rafael José; Pham-Thi, Nhân; Antó, Josep M.; Czarlewski, Wienczyslawa; Sá-Sousa, Ana; Amaral, Rita; Bedbrook, Anna; Bosnic-Anticevich, Sinthia; Brussino, Luisa; Canonica, G. Walter; Cecchi, Lorenzo; Cruz, Álvaro A.; Fokkens, Wytske J.; Gemicioglu, Bilun; Haahtela, Tali; Ivancevich, Juan Carlos; Klimek, Ludger; Kuna, Piotr; Kvedariene, Violeta; Larenas Linnemann, Désirée; Morais-Almeida, Mario; Mullol, Joaquim; Niedoszytko, Marek; Okamoto, Yoshitaka; Papadopoulos, Nikolaos G.; Patella, Vincenzo; Pfaar, Oliver; Regateiro, Frederico S.; Reitsma, Sietze; Rouadi, Philip W.; Samolinski, Boleslaw; Sheikh, Aziz; Taborda Barata, Luis; Toppila-Salmi, Sanna; Sastre, Joaquín; Tsiligianni, Ioanna; Valiulis, Arunas; Ventura, María Teresa; Waserman, Susan; Yorgancioglu, Arzu; MASK Study Group; Sousa Pinto, Bernardo; Zidarn, Mihaela; Zuberbier, Torsten; Fonseca, João A.; Bousquet, Jean (Fecha de publicación: 2024-03-25)

    BACKGROUND: Several studies have suggested an impact of allergic rhinitis on academic productivity. However, large studies with real-world data (RWD) are not available. OBJECTIVE: To use RWD to assess the impact of allergic ...

    Interlink between Inflammation and Oxidative Stress in Age-Related Macular Degeneration: Role of Complement Factor H 

    Romero Vázquez, Sara; Llorens Bellés, Víctor; Soler Boronat, Alba; Figueras Roca, Marc; Adán Civera, Alfredo; Molins Monteys, Blanca (Fecha de publicación: 2025-03-14)

    Age-related macular degeneration (AMD) heads the list of legal blindness among the elderly population in developed countries. Due to the complex nature of the retina and the variety of risk factors and mechanisms involved, ...

    Resistance mechanisms and molecular epidemiology of Pseudomonas aeruginosa strains from patients with bronchiectasis 

    Cabrera Ortega, Roberto; Fernández Barat, Laia; Vázquez, Nil; Alcaraz-Serrano V; Bueno Freire, Leticia; Amaro, Rosanel; López Aladid, Rubén; Oscanoa, Patricia; Muñoz López, Laura; Vila Estapé, Jordi; Torres Martí, Antoni (Fecha de publicación: 2022-04-01)

    Non-cystic fibrosis bronchiectasis (BE) is a chronic structural lung condition that facilitates chronic colonization by different microorganisms and courses with recurrent respiratory infections and frequent exacerbations. ...

    Physiological lentiviral vectors for the generation of improved CAR-T cells 

    Tristán Manzano, María; Maldonado Pérez, Noelia; Justicia Lirio, Pedro; Muñoz, Pilar; Cortijo Gutiérrez, Marina; Pavlovic, Kristina; Jiménez Moreno, Rosario; Nogueras, Sonia; Carmona, M. Dolores; Sánchez Hernández, Sabina; Aguilar Gonzalez, Araceli; Castellà Castellà, Maria; Juan, Manel; Marañón, Concepción; Marchal, Juan Antonio; Benabdellah, Karim; Herrera, Concha; Martín, Francisco (Fecha de publicación: 2023-07-26)

    Anti-CD19 chimeric antigen receptor (CAR)-T cells have achieved impressive outcomes for the treatment of relapsed and refractory B-lineage neoplasms. However, important limitations still remain due to severe adverse events ...

    Postsurgical Cerebral Perfusion Changes in Idiopathic Normal Pressure Hydrocephalus: A Statistical Parametric Mapping Study of SPECT Images 

    Mataró Serrat, Maria; Poca Pastor, María Antonia; Salgado-Pineda, Pilar; Castell Conesa, Joan; Sahuquillo, Juan; Díez Castro, María Jesús; Aguadé Bruix, Santiago; Vendrell i Gómez, Pere; Matarín, Mar; Junqué i Plaja, Carme, 1955- (Fecha de publicación: 2025-09-29)

    Our goal was to study cerebral blood flow (CBF) changes after surgery in a group of 15 patients with idiopathic normal pressure hydrocephalus (NPH). Methods: We used hexamethylpropyleneamine oxime SPECT and statistical ...

    Lifetime psychotic symptoms, subthreshold depression and cognitive impairment as barriers to functional recovery in patients with bipolar disorder 

    Bonnín Roig, Caterina del Mar; Jiménez Martínez, Ester; Solé Cabezuelo, Brisa; Torrent Font, Carla; Radua, Joaquim; Reinares, María; Grande i Fullana, Iria; Ruíz, Victoria; Sánchez-Moreno, José; Martínez-Arán, Anabel, 1971-; Vieta i Pascual, Eduard, 1963- (Fecha de publicación: 2020-04-21)

    Background: bipolar disorder (BD) is a chronic disease that often leads to functional impairment. The objective of this study is to elucidate which variables are associated with better functional outcomes in a sample of ...

    Usefulness of Transcriptional Blood Biomarkers as a Non-invasive Surrogate Marker of Mucosal Healing and Endoscopic Response in Ulcerative Colitis 

    Planell Picola, Núria; Masamunt, Maria Carme; Franco Leal, Raquel; Rodríguez Rubio, Lorena; Esteller Viñal, Miriam; Lozano Salvatella, Juan José; Ramírez Morros, Anna; Setsuko Ayrizono, Maria de Lourdes; Coy, Claudio Saddy Rodrigues; Alfaro, Ignacio; Ordas, Ingrid; Visvanathan, Sudha; Ricart, Elena; Guardiola, Jordi; Panes, Julian; Salas Martínez, Azucena (Fecha de publicación: 2025-07-03)

    Background and Aims: Ulcerative colitis [UC] is a chronic inflammatory disease of the colon. Colonoscopy remains the gold standard for evaluating disease activity, as clinical symptoms are not sufficiently accurate. The ...

    Influence of Music on Anxiety Induced by Fear of Heights in Virtual Reality 

    Seinfeld, Sofia; Bergstrom, Ilias; Pomés Freixa, Ausiàs; Arroyo Palacios, Jorge; Vico, Francisco; Slater, Mel; Sánchez-Vives, María Victoria (Fecha de publicación: 2019-01-23)

    Music is a potent mood regulator that can induce relaxation and reduce anxiety in different situations. While several studies demonstrate that certain types of music have a subjective anxiolytic effect, the reported results ...

    Improved classification of leukemic B-cell lymphoproliferative disorders using a transcriptional and genetic classifier 

    Navarro, Alba; Clot Razquin, Guillem; Martínez Trillos, Alejandra; Pinyol, Magda; Jares Gerboles, Pedro; González Farré, Blanca; Martínez, Daniel; Trim, Nicola; Fernàndez Pascual, Verònica; Villamor i Casas, Neus; Colomer Pujol, Dolors; Costa, Dolors; Salaverria Frigola, Itziar; Martín García, David; Erber, Wendy; López González, Cristina; Jayne, Sandrine; Siebert, Reiner; Dyer, Martin J. S.; Wiestner, Adrian; Wilson, Wyndham H.; Aymerich Gregorio, Marta; López Guillermo, Armando; Sànchez, Àlex (Sànchez Pla); Campo Güerri, Elias; Matutes, Estella; Beà Bobet, Sílvia M. (Fecha de publicación: 2018-06-11)

    B-cell chronic lymphoproliferative disorders (B-CLPD) encompass a group of hematologic tumors that often present with leukemic involvement.1 Their heterogeneity and the lack of relatively specific diagnostic markers for ...

    People with type 1 diabetes exhibit lower exercise capacity compared to a control population with similar physical activity levels 

    Murillo, Serafín; Brugnara, Laura; Ríos, Santiago; Ribas, Vicent; Servitja, Joan Marc; Novials, Anna (Fecha de publicación: 2025-02-20)

    Aims: We aimed to assess physical activity (PA) levels, adherence to PA guidelines, and fitness capacity in individuals with type 1 diabetes (T1D) and control population. Methods: This cross-sectional study included 232 ...

    Emotional intelligence: A comparison between patients after first episode mania and those suffering from chronic bipolar disorder type i 

    Varo, Cristina; Amoretti Guadall, Silvia; Sparacino, Giulio; Jiménez Martínez, Ester; Solé Cabezuelo, Brisa; Bonnín Roig, Caterina del Mar; Montejo Egido, Laura; Serra Navarro, Maria; Torrent Font, Carla; Salagre Muñoz, Estela; Benabarre, Antonio; Salgado Pineda, Pilar; Montoro Salvatierra, Irene; Sáiz Martínez, Pilar Alejandra; García Portilla, María Paz; Sánchez Gistau, Vanessa; Pomarol-Clotet, Edith; Ramos Quiroga, Josep Antoni; Pacchiarotti, Isabella; García Rizo, Clemente; Undurraga Fourcade, Juan Pablo; Reinares, María; Martínez-Arán, Anabel, 1971-; Vieta i Pascual, Eduard, 1963-; Verdolini, Norma (Fecha de publicación: 2024-04-23)

    Deficits in emotional intelligence (EI) were detected in patients with Bipolar Disorder (BD), but little is known about whether these deficits are already present in patients after presenting a first episode mania (FEM). ...

    Metazoan evolution of glutamate receptors reveals unreported phylogenetic groups and divergent lineage-specific events 

    Ramos Vicente, David; Ji, Jie; Gratacòs i Batlle, Esther; Gou, Gemma; Reig Viader, Rita; Luís, Javier; Burguera, Demian; Navas Pérez, Enrique; García Fernández, Jordi; Fuentes Prior, Pablo; Escriva, Hector; Roher Armentia, Nerea; Soto del Cerro, David; Bayés, Àlex (Fecha de publicación: 2020-04-24)

    Glutamate receptors are divided in two unrelated families: ionotropic (iGluR), driving synaptic transmission, and metabotropic (mGluR), which modulate synaptic strength. The present classification of GluRs is based on ...

    Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma 

    Schmitz, Roland; Wright, George W.; Huang, Da Wei; Johnson, Calvin; Phelan, James D.; Wang, James Q.; Roulland, Sandrine; Kasbekar, Monica; Young, Ryan M; Shaffer, Art; Hodson, Daniel J.; Xiao, Wenming; Yu, Xin; Yang, Yandan; Zhao, Hong; Xu, Weihong; Liu, Xuelu; Zhou, Bin; Du, Wei; Chan, Wing C.; Jaffe, Elaine S.; Gascoyne, Randy D.; Connors, Joseph M.; Campo Güerri, Elias; López Guillermo, Armando; Rosenwald, Andreas; Ott, German; Delabie, Jan; Rimsza, Lisa; Tay Kuang Wei, Kevin; Zelenetz, Andrew D.; Leonard, John P.; Bartlett, Nancy L.; Tran, Bao; Shetty, Jyoti; Zhao, Yongmei; Soppet, Dan R.; Pittaluga, Stefania; Wilson, Wyndham H.; Staudt, Louis M. (Fecha de publicación: 2019-06-19)

    BACKGROUND Diffuse large B-cell lymphomas (DLBCLs) are phenotypically and genetically heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B-cell-like [ABC], germinal-center B-cell-like ...

    Impact of SARS-CoV-2 pandemic on vascular liver diseases 

    Baiges Aznar, Anna; Cerda, Eira; Amicone, Caroline; Tellez, Luis; Alvarado Tapias, Edilmar; Puente, Angela; Fortea, Jose Ignacio; Llop, Elba; Rocha, Filipa; Orts, Lara; Ros Fargas, Olivia; Vizcarra, Pamela; Zekrini, Kamal; Amara Lounes, Ould; Touati, Ghiles; Jimenez, Natalia; Serrano, Maria Jose; Falgà, Àngels; Magaz Martínez, Marta; Olivas, Pol; Betancourt, Fabian; Pérez Campuzano, Valeria; Turon, Fanny; Payancé, Audrey; Goria, Odile; Rautou, Pierre-Emmanuel; Hernández Gea, Virginia; Villanueva, Càndid; Albillos, Agustín; Plessier, Aurélie; García Pagán, Juan Carlos (Fecha de publicación: 2022-01-13)

    Vascular liver diseases (VLD) are represented mainly by portosinusoidal vascular disease (PSVD), non-cirrhotic splanchnic vein thrombosis (SVT) and Budd Chiari syndrome (BCS). It is unknown whether patients with VLD ...

    No need for secondary Pneumocystis jirovecii pneumonia prophylaxis in adult people living with HIV from Europe on ART with suppressed viraemia and a CD4 cell count greater than 100 cells/µL 

    Atkinson, Andrew; Miró Meda, José M. (José María), 1956-; Mocroft, Amanda; Reiss, Peter; Kirk, Ole; Morlat, Philippe; Ghosn, Jade; Stephan, Christoph; Mussini, Cristina; Antoniadou, Anastasia; Doerholt, Katja; Girardi, Enrico; Wit, Stéphane de; Kraus, David; Zwahlen, Marcel; Noguera Julian, Antoni; Furrer, Hansjakob; Collaboration of Observational HIV Epidemiological (Fecha de publicación: 2022-03-15)

    Introduction: Since the beginning of the HIV epidemic in resource-rich countries, Pneumocystis jirovecii pneumonia (PjP) is one of the most frequent opportunistic AIDS-defining infections. The Collaboration of Observational ...

    Cost-effectiveness of Alzheimer's disease CSF biomarkers and amyloid-PET in early-onset cognitive impairment diagnosis 

    Contador Muñana, José Miguel; Vargas Martinez, A. M.; Sánchez Valle, Raquel; Trapero Bertran, M.; Lladó Plarrumaní, Albert (Fecha de publicación: 2024-01-24)

    This study aimed at determining the cost-effectiveness of amyloid-positron emission tomography (PET) compared to Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers (amyloid-?42, total-Tau and phosphorylated-Tau) ...

    From Genetics to Psychosocial Functioning: Unraveling the Mediating Roles of Cognitive Reserve Cognition and Negative Symptoms in First-Episode Psychosis 

    Segura, Alex G.; Forte, Maria Florencia; Clougher, Derek; Mezquida Mateos, Gisela; Sánchez Torres, Ana M.; Vieta i Pascual, Eduard, 1963-; Garriga, Marina; Lobo, Antonio; González-Pinto, Ana; Díaz Caneja, Covadonga M.; Roldán, Alexandra; Martinez Aran, Anabel; de la Serna Gómez, Elena; Mané Santacana, Anna; Mas Herrero, Sergi; Torrent Font, Carla; Allot, Kelly; Bernardo Arroyo, Miquel; Amoretti Guadall, Silvia; PEPs Group (Fecha de publicación: 2025-03-05)

    Background: Studies have shown associations between polygenic risk scores for educational attainment (PRSEA), cognitive reserve (CR), cognition, negative symptoms (NS), and psychosocial functioning in first-episode psychosis ...