IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer: Recent submissions
Now showing items 441-460 of 3164
Manual motor speed dysfunction as a neurocognitive endophenotype in euthymic bipolar disorder patients and their healthy relatives. Evidence from a 5-year follow-up study
Background Few studies have examined Manual Motor Speed (MMS) in bipolar disorder (BD). The aim of this longitudinal, family study was to explore whether dysfunctional MMS represents a neurocognitive endophenotype of ...
Rheumatoid nodule mimicking an olecranon bursitis as the primary manifestation of rheumatoid arthritis
Olecranon bursitis is a relatively common condition, being most of the cases idiopathic. Less commonly it is caused by infection, by a systemic inflammatory process or by a crystal-deposition disease such as gout or ...
Complete response under sorafenib in patients with hepatocellular carcinoma: Relationship with dermatologic adverse events.
The clinical benefit of sorafenib in patients with hepatocellular carcinoma (HCC) has been undervalued due to the absence of complete responses, even though patients who develop early dermatologic reactions have shown to ...
Postnatal persistence of fetal cardiovascular remodelling associated with assisted reproductivetechnologies: a cohort study
OBJECTIVE: To assess the postnatal persistence of fetal cardiovascular remodelling associated with assisted reproductive technologies (ART) in children at 3 years of age. DESIGN: A cohort study of children conceived by ...
TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics
Chronic lymphocytic leukemia is associated with a highly heterogeneous disease course in terms of clinical outcomes and responses to chemoimmunotherapy. This heterogeneity is partly due to genetic aberrations identified ...
Fractionated initial infusion and booster dose of ARI0002h, a humanised, BCMA-directed CART-cell therapy, for patients with relapsed or refractory multiple myeloma (CARTBCMA- HCB-01): a single-arm, multicentre, academic pilot study
Background Chimeric antigen receptor (CAR) T-cell therapy is a promising option for patients with heavily treated multiple myeloma. Point-of-care manufacturing can increase the availability of these treatments worldwide. ...
Validation of walking trails for the Urban Training of chronic obstructive pulmonary disease patients.
Purpose Accessible interventions to train patients with chronic obstructive pulmonary disease (COPD) are needed. We designed urban trails of different intensities (low, moderate and high) in different types of public spaces ...
Cortical thinning over two years after first-episode psychosis depends on age of onset
First-episode psychosis (FEP) patients show structural brain abnormalities at the first episode. Whether the cortical changes that follow a FEP are progressive and whether age at onset modulates these changes remains ...
Outcome measures in muscular dystrophy rehabilitation: an ICF content comparison approach to the most commonly used MD scales
Introduction: Functioning is the reason to be of rehabilitation as it is essential to the lives of people who suffer from a disease. The International Classification of Functioning, Disability and Health (ICF) can help in ...
Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder.
There has been substantial progress in the development of regenerative medicine strategies for central nervous system disorders over the last decade, with progression to early clinical studies for some conditions. However, ...
A phase II trial of lenalidomide, dexamethasone and cyclophosphamide for newly diagnosed patients with systemic immunoglobulin light chain amyloidosis
Immunomodulatory drugs have been shown to be of benefit in relapsed/refractory immunoglobulin light-chain (AL) amyloidosis. We designed a prospective, multicentre phase II trial of lenalidomide, dexamethasone and ...
Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes
Major depressive disorder (MDD) is a common disorder with a variety of symptoms including mood alterations, anhedonia, sleep and appetite disorders, and cognitive disturbances. Stressful life events are among the strongest ...
The Effects of Vegetarian and Vegan Diet during Pregnancy on the Health of Mothers and Offspring
Vegetarian and vegan diets have increased worldwide in the last decades, according to the knowledge that they might prevent coronary heart disease, cancer, and type 2 diabetes. Althought plant-based diets are at risk of ...
INTERGROWTH-21st versus a customized method for the prediction of neonatal nutritional status in hypertensive disorders of pregnancy
Background: Hypertensive disorders of pregnancy (HDP) generate complications and are one of the principal causes of maternal, foetal, and neonatal mortality worldwide. It has been observed that in pregnancies with HDP, the ...
Corrigendum: Structural Brain Network Reorganization and Social Cognition Related to Adverse Perinatal Condition from Infancy to Early Adolescence
In the original article, we omitted a reference to Réveillon et al. (2016) regarding the description of the neuropsychological tests performed by the children and the association between IUGR and hyperactivity/inattention ...
Subtle visuomotor difficulties in preclinical Alzheimer's disease
Background: Individuals with preclinical Alzheimer's disease (Pre-AD) present nonimpaired cognition, as measured by standard neuropsychological tests. However, detecting subtle difficulties in cognitive functions may be ...
Hepatitis C-related cirrhosis will be a marginal cause of hospital admissions by 2025
Background & Aims Complications of cirrhosis are the main cause of hospital admissions in liver units. In areas where HCV is prevalent, most of these admissions are attributable to HCV-related cirrhosis (HCV-cirrhosis). ...
