Cyclophosphamide-free Mobilisation Increases Safety While Preserving the Efficacy of Autologous Haematopoietic Stem Cell Transplantation in Refractory Crohn's Disease Patients 

Giordano, Antonio; Rovira Tarrats, Montserrat; Veny Álvarez-Ossorio, Marisol; Barastegui Baget, Rebeca; Marín Fernández, Pedro José; Martínez Muñoz, Ma. Carmen; Fernández Avilés, F.; Suárez-Lledó Grande, María; Domenech, Ariadna; Serrahima, Anna; Lozano Molero, Miguel; Cid Vidal, Joan; Ordas Jimenez, Ingrid; Fernández Clotet, Agnès; Caballol Oliva, Berta; Gallego Barrero, Marta; Vara, Alejandro; Masamunt, Maria Carme; Giner Agudo, Àngel; Teubel, Iris; Esteller Viñal, Miriam; Corraliza Márquez, Ana Maria; Panés Díaz, Julià; Salas Martínez, Azucena; Ricart, Elena (Ricart Gómez) (Publication date: 2024-11-18)

Background and Aim Autologous haematopoietic stem cell transplantation [AHSCT] is a therapeutic option for refractory Crohn's disease [CD]. However, high adverse event rates related to chemotherapy toxicity and immunosuppression ...

Preferential regional distribution of atrial fibrosis in posterior wall around left inferior pulmonary vein as identified by late gadolinium enhancement cardíac magnetic resonance in patients with atrial fibrillation 

Benito, Eva; Cabanelas, Nuno; Nuñez-Garcia, Marta; Alarcón, Francisco; Figueras i Ventura, Rosa M.; Soto Iglesias, David; Guasch i Casany, Eduard; Prat González, Susanna; Perea Palazón, Rosario Jesús; Borràs, Roger; Butakoff, Constantine; Camara, Oscar; Bisbal, Felipe; Arbelo, Elena; Tolosana, José M. (José María); Brugada Terradellas, Josep, 1958-; Berruezo Sánchez, Antonio; Mont Girbau, Lluís (Publication date: 2019-04-11)

Aims: Left atrial (LA) fibrosis can be identified by late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) in patients with atrial fibrillation (AF). However, there is limited information about anatomical fibrosis ...

A loud auditory stimulus overcomes voluntary movement limitation in cervical dystonia 

Serranová, Tereza; Jech, Robert; Martí Domènech, Ma. Josep; Modreanu, Raluca; Valldeoriola Serra, Francesc; Sieger, Tomá; Ruzicka, Evzen; Valls Solé, Josep (Publication date: 2018-09-19)

Background Patients with cervical dystonia (CD) present with an impaired performance of voluntary neck movements, which are usually slow and limited. We hypothesized that such abnormality could involve defective preparation ...

Low-cost, easy-to-build noninvasive pressure support ventilator for under-resourced regions: open source hardware description, performance and feasibility testing 

Garmendia, Onintza; Rodríguez Lazaro, Miguel A.; Otero Díaz, Jorge; Phan, Phuong; Stoyanova, Alexandrina Petrova; Dinh-Xuan, Anh Tuan; Gozal, David; Navajas Navarro, Daniel; Montserrat, Josep M.; Farré Ventura, Ramon (Publication date: 2021-01-11)

Aim: Current pricing of commercial mechanical ventilators in low-/middle-income countries (LMICs) markedly restricts their availability, and consequently a considerable number of patients with acute/chronic respiratory ...

Bepirovirsen - a new therapy for chronic Hepatitis B Infection 

Lens García, Sabela (Publication date: 2023-12-11)

Microscopic fractional anisotropy outperforms multiple sclerosis lesion assessment and clinical outcome associations over standard fractional anisotropy tensor 

Vivó, Francesc; Solana Díaz, Elisabeth; Calvi, Alberto; López Soley, Elisabet; Reid, Lee B.; Pascual-Diaz, Saül; Garrido, César; Planas Tardido, Laura; Cabrera Maqueda, Jose Maria; Alba Arbalat, Salut; Sepúlveda, María; Blanco Morgado, Yolanda; Kanber, Baris; Prados, Ferran; Saiz Hinarejos, Albert; Llufriu Duran, Sara; Martinez-Heras, Eloy (Publication date: 2025-05-23)

We aimed to compare the ability of diffusion tensor imaging and multi-compartment spherical mean technique to detect focal tissue damage and in distinguishing between different connectivity patterns associated with varying ...

Gastrointestinal Symptoms: Under the Tip of the Iceberg in Lipid Transfer Protein Food Allergy 

Ruano Zaragoza, Maria; Araujo Sánchez, Giovanna; Gelis, Sònia; Loli Ausejo, David Enrique; Mir Ihara, Patricia Karina; Mascaró Hereza, Berta; Sánchez Fernández, M.C.; Pascal i Capdevila, Mariona; Muñoz-Cano, Rosa; Bartra Tomàs, Joan (Publication date: 2026-03-02)

Gastrointestinal symptoms (GIS) have been reported to be a manifestation of IgE-mediated food allergy (FA), although epidemiologic data are limited. Patients with FA caused by lipid transfer proteins (LTP-FA) may react to ...

Accuracy of colon capsule endoscopy in detecting colorectal polyps in individuals with familial colorectal cancer: could we avoid colonoscopies? 

Alvarez Urturi, Cristina; Fernández Esparrach, Glòria; Ibáñez, Inés Ana; Rodríguez de Miguel, Cristina; Dedeu, Josep Maria; Bessa i Caserras, Xavier; Córdova, Henry; Pellisé Urquiza, Maria; Balaguer Prunés, Francesc; Ginès i Gibert, M. Àngels; Barranco, Luis; Araujo, Isis Karina; Andreu, Montserrat; Llach Vila, Josep; Castells Garangou, Antoni; González Suárez, Begoña (Publication date: 2018-03-02)

Background. Individuals with a family history of colorectal cancer (CRC) have an increased risk of CRC. We evaluated the diagnostic yield of CCE in the detection of lesions and also two different colon preparations. Methods. ...

TRPV2: A Key Player in Myelination Disorders of the Central Nervous System 

Enrich Bengoa, Jennifer; Manich Raventós, Gemma; Valente, Tony; Sanchez Molina, Paula; Almolda, Beatriz; Solà i Subirana, Carme; Saura Martí, Josep; González, Berta; Castellano, Bernardo; Perálvarez Marín, Alex (Publication date: 2022-05-17)

Transient potential receptor vanilloid 2 (TRPV2) is widely expressed through the nervous system and specifically found in neuronal subpopulations and some glial cells. TRPV2 is known to be sensitized by methionine oxidation, ...

Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients 

Cervera i Segura, Ricard, 1960-; Serrano, R.; Pons-Estel, G. J.; Ceberio-Hualde, L.; Shoenfeld, Y.; de Ramón, Enrique; Buonaiuto, V.; Jacobsen, Søren; Zeher, M. M.; Tarr, T.; Tincani, Angela; Taglietti, M.; Theodossiades, G.; Nomikou, E.; Galeazzi, M.; Meroni, Pierluigi; Derksen, R. H. W. M.; de Groot, P. G. D.; Baleva, M.; Mosca, Marta; Bombardieri, S.; Houssiau, Frédéric A.; Gris, J-C.; Quéré, I.; Hachulla, Eric; Vasconcelos, Carlos; Fernández-Nebro, Antonio; Haro, M.; Amoura, Zahir; Miyara, M.; Tektonidou, Maria; Espinosa Garriga, Gerard; Bertolaccini, M. L.; Khamashta, Munther A.; Bellisai, F. (Publication date: 2018-02-08)

OBJECTIVES: To assess the prevalence of the main causes of morbi-mortality in the antiphospholipid syndrome (APS) during a 10-year-follow-up period and to compare the frequency of early manifestations with those that ...

Treating HIV-Positive/Non-AIDS Patients for Community-Acquired Pneumonia with ART 

Cillóniz, Catia; Ielpo, Antonella; Torres Martí, Antoni (Publication date: 2019-11-12)

Purpose of Review: This article reviews the most recent publications on community-acquired pneumonia (CAP) in the HIV-infected population on antiretroviral therapy (ART), focusing on epidemiology, prognostic factors, ...

Melanoma-specific survival is worse in the elderly: a multicentric cohort study 

Segura, Sonia; Podlipnik, Sebastian; Boada, Aram; Martí, Rosa M.; Sabat, Mireia; Yélamos, Oriol; Zarzoso Muñoz, Inés; Azón Masoliver, Antoni; López Castillo, Daniel; Solà, Joaquim; Baliu Piqué, Carola; Galvany Rossell, Loida; Pasquali, Paola; Just Sarobé, Miquel; Duran, Xavier; Carrera Álvarez, Cristina; Richarz, Nina A.; Pujol, Ramon M.; Malvehy, J. (Josep); Network Melanoma Ctr Catalonia; Puig i Sardà, Susana (Publication date: 2024-03-25)

We aimed to characterise cutaneous melanoma in the elderly and determine its association with poorer prognosis. We studied a prospective cohort of the melanoma population in Catalonia between 2012 and 2016. We compared ...

In Memory of Hagop Akiskal 

Carta, Mauro Giovanni; Colom, Francesc, 1971-; Erfurth, Andreas; Fornaro, Michele; Grunze, Heinz; Hantouche, Elie; Nardi, Antonio E.; Preti, Antonio; Vieta i Pascual, Eduard, 1963-; Karam, Elie (Publication date: 2022-05-25)

The death of Hagop Akiskal left a great void in all who knew him, and many of us knew him, indeed, all over the world. Hagop was an attentive clinician and innovative researcher as well as a mentor who accompanied the ...

Evaluation of microvascular changes in the perifoveal vascular network using optical coherence tomography angiography (OCTA) in type I diabetes mellitus: a large scale prospective trial 

Zarranz Ventura, Javier; Barraso, Marina; Alé Chilet, Aníbal Raimundo; Hernandez, Teresa; Oliva, Cristian; Gascon, Jesus; Sala Puigdollers, Anna; Figueras Roca, Marc; Vinagre, Irene; Ortega Martínez de Victoria, Emilio; Esmatjes Mompó, Enric; Adán Civera, Alfredo (Publication date: 2020-05-29)

Background: Diabetic retinopathy (DR) is the leading cause of blindness in type 1 Diabetes Mellitus (DM) patients, as a consequence of impaired blood flow in the retina. Optical coherence tomography angiography (OCTA) is ...

Altered Temporal Dynamics of Resting-State Functional Magnetic Resonance Imaging in Adolescent-Onset First-Episode Psychosis 

Masias, Mireia; Ramírez Mahaluf, Juan Pablo; Valli, Isabel; Ortuño Candela, Maria; Ilzarbe, Daniel; Serna, Elena de la, 1978-; Puig Navarro, Olga; Crossley, Nicholas A.; González Ballester, Miguel Ángel; Baeza, Inmaculada, 1970-; Piella, Gemma; Castro Fornieles, Josefina; Sugranyes, Gisela (Publication date: 2023-11-17)

Background Dynamic functional connectivity (dFC) alterations have been reported in patients with adult-onset and chronic psychosis. We sought to examine whether such abnormalities were also observed in patients with first ...

The Barcelona brain health initiative: A cohort study to define and promote determinants of brain health. 

Cattaneo, Gabriele; Bartrés Faz, David; Morris, Timothy Peter; Solana Sánchez, Javier; Macià Bros, Dídac; Tarrero, Clara; Tormos, José María; Pascual Leone, Álvaro, 1961- (Publication date: 2019-12-02)

The Barcelona Brain Health Initiative (BBHI) is an ongoing prospective longitudinal study focused on identifying determinants of brain health. The main objectives are: (i) to characterize lifestyle, cognitive, behavioral ...

Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer 

Castells Garangou, Antoni; Castellví Bel, Sergi; The COGENT Consortium; The CORGI Collaborators; The EPICOLON Consortium (Publication date: 2020-01-22)

Genome-wide association studies (GWAS) have identified 14 tagging single nucleotide polymorphisms (tagSNPs) that are associated with the risk of colorectal cancer (CRC), and several of these tagSNPs are near bone morphogenetic ...

Risk factors for mortality in patients with acute leukemia and bloodstream infections in the era of multiresistance 

Garcia Vidal, Carolina; Cardozo Espinola, Celia; Puerta-Alcalde, Pedro; Marco Reverté, Francesc; Tellez, Adrian; Agüero, Daiana; Romero Santana, Francisco; Díaz Beyà, Marina; Giné Soca, Eva; Morata, Laura; Rodríguez Núñez, Olga; Martínez, José Antonio; Mensa Pueyo, Josep; Esteve Reyner, Jordi; Soriano Viladomiu, Alex (Publication date: 2019-02-20)

Objectives: We assess the epidemiology and risk factors for mortality of bloodstream infection (BSI) in patients with acute leukemia (AL). Methods: Prospectively collected data of a cohort study from July 2004 to February ...

Relationship between the use of inhaled steroids for chronic respiratory diseases and early outcomes in community-acquired pneumonia. 

Almirall, Jordi; Bolibar, Ignasi; Serra Prat, Mateu; Palomera Fanegas, Elisabet; Roig, Jordi; Hospital, Imma; Carandell, Eugenia; Agustí, Mercè; Ayuso, Pilar; Estela, Andreu; Torres Martí, Antoni; Community-Acquired Pneumonia in Catalan Countries (Publication date: 2018-09-20)

Background The role of inhaled steroids in patients with chronic respiratory diseases is a matter of debate due to the potential effect on the development and prognosis of community-acquired pneumonia (CAP). We assessed ...

Cell-Free DNA for Genomic Analysis in Primary Mediastinal Large B-Cell Lymphoma 

Rivas Delgado, Alfredo; Nadeu Prat, Ferran; Andrade Campos Marcio; López González, Cristina; Enjuanes, Anna; Mozas, Pablo; Frigola, Gerard; Colomo Saperas, Lluís; Sánchez González, Blanca; Villamor i Casas, Neus; Beà Bobet, Sílvia M.; Campo Güerri, Elias; Salar, Antonio; Giné Soca, Eva; López Guillermo, Armando; Bellosillo Paricio, Beatriz (Publication date: 2023-07-04)

High-throughput sequencing of cell-free DNA (cfDNA) has emerged as a promising noninvasive approach in lymphomas, being particularly useful when a biopsy specimen is not available for molecular analysis, as it frequently ...