Prognostic Value of Serum Paraprotein Response Kinetics in Patients With Newly Diagnosed Multiple Myeloma 

Tamariz Amador, Luis Esteban; Rodríguez Otero, Paula; Jiménez Ubieto, Ana; Rosiñol Dachs, Laura; Oriol, Albert; Ríos, Rafael; Sureda, Anna; Blanchard, Maria Jesus; Hernández, Miguel Teodoro; Cabañas Perianes, Valentin; Jarque, Isidro; Bargay, Joan; Gironella, Mercedes; De Arriba, Felipe; Palomera, Luis; Gonzalez Montes, Yolanda; Martí, Josep M.; Krsnik, Isabel; Arguiñano, José María; González, María Esther; Casado, Luis Felipe; González Rodriguez, Ana Pilar; López Anglada, Lucía; Puig, Noemi; Cedena, Maria Teresa; Paiva, Bruno; Mateos, María Victoria; San Miguel, Jesús; Lahuerta, Juan José; Bladé, J. (Joan); Trocóniz, Iñaki F. (Publication date: 2022-11-14)

Response kinetics is not well-established as a prognostic marker in multiple myeloma (MM). We developed a mathematical model to assess the prognostic value of serum monoclonal component (MC) response kinetics during 6 ...

Commensal-Specific CD4(+) Cells From Patients With Crohn's Disease Have a T-Helper 17 Inflammatory Profile 

Calderón Gómez, Elisabeth; Bassolas Molina, Helena; Mora Buch, Rut; Dotti, Isabella; Planell Picola, Núria; Esteller Viñal, Miriam; Gallego Barrero, Marta; Martí Ripoll, Maria Mercè; Garcia Martin, Carme; Martínez Torro, Carlos; Ordas, Ingrid; Singh, Sharat; Panes, Julian; Benítez-Ribas, Daniel; Salas Martínez, Azucena (Publication date: 2025-07-07)

BACKGROUND & AIMS: Crohn's disease (CD) has been associated with an altered immune response to commensal microbiota, mostly based on increased seroreactivity to microbial proteins. Although T cells are believed to contribute ...

Differential tDCS and tACS Effects on Working Memory-Related Neural Activity and Resting-State Connectivity 

Abellaneda Pérez, Kilian; Vaqué Alcázar, Lídia; Perellón Alfonso, Ruben; Bargalló Alabart, Núria; Kuo, Min Fang; Pascual Leone, Álvaro, 1961-; Nitsche, Michael A.; Bartrés Faz, David (Publication date: 2021-04-22)

Transcranial direct and alternating current stimulation (tDCS and tACS, respectively) entail capability to modulate human brain dynamics and cognition. However, the comparability of these approaches at the level of large-scale ...

Treatment retention in a specialized alcohol programme after an episode of alcoholic hepatitis: Impact on alcohol relapse 

López Pelayo, Hugo; Miquel de Montagut, Laia; Altamirano, José; Bataller Alberola, Ramón; Caballeria Rovira, Joan; Ortega, Lluisa; Lligoña, Anna; Gual, Antoni (Publication date: 2020-03-03)

Aims: Alcoholic hepatitis (AH) is a life-threatening complication of alcohol use disorder (AUD). Alcohol abstinence is the main predictor of the long-term prognosis of AH. It is unknown whether AUD treatment retention (TR) ...

Massive Neonatal Arterial Ischemic Stroke 

Arca, Gemma; Núñez, Christian; Stephan Otto, Christian; Arnaez, Juan; Agut, Thais; Cordeiro, Malaika; Boronat, Nuria; Lubián López, Simón; Benavente Fernández, Isabel; Valverde, Eva; García-Alix Pérez, Alfredo (Publication date: 2024-01-08)

Do ART and chemsex drugs get along? Potential drug-drug Interactions in a cohort of people living with HIV who engaged in chemsex: a retrospective observational study.  

Mora, Lorena de la; Nebot, María J.; Martínez Rebollar, María; Lazzari, Elisa de; Tuset Creus, Montserrat; Laguno Centeno, Montserrat; Ambrosioni, Juan; Miquel, Laia; Blanch Andreu, Jordi; Ugarte Ramos, Ainoa; Torres Murillo, Berta; González, Ana; Inciarte Portillo, Alexy; Chivite, Ivan; Short, Duncan; Salgado García, Emilio José; Martinez, Esteban; Blanco, José L.; Mallolas Masferrer, Josep (Publication date: 2024-04-17)

Introduction: People living with HIV (PLWH) who engaged in chemsex are at risk of potential drug-drug interactions (pDDIs) with recreational drugs. This study aimed to characterize pDDIs between antiretroviral treatment ...

Alterations in the abundance of protamine proteoforms related to sperm chromatin packaging, obesity, and age in normozoospermic men 

Castillo Corullón, Judit; Gay i Marín, Marina; Iglesia Rodríguez, Alberto de la; Arauz-Garofalo, Gianluca; Vilanova, Mar; Leiva, Marina; Corral Molina, Juan Manuel; Guimerà, Marta; Manau Trullàs, Dolors; Vilaseca, Marta; Jodar Bifet, Meritxell; Oliva Virgili, Rafael (Publication date: 2025-06-25)

Protamines are considered among the most relevant sperm proteins because of their functional implications on paternal genome packaging and protection. Although the proteomic evaluation of protamines is technically challenging, ...

Community-Acquired Legionella Pneumonia in Human Immunodeficiency Virus-Infected Adult Patients: A Matched Case-Control Study 

Cillóniz, Catia; Miguel Escuder, Lucia; Pedro Bonet, María Luisa; Falcó, Vicenç; Lopez, Yessica; Garcia Vidal, Carolina; Gabarrús, Albert; Moreno Camacho, Ma. Asunción; Torres Martí, Antoni; Miró Meda, José M. (José María), 1956- (Publication date: 2019-07-05)

We investigate whether the clinical presentations and outcomes of Legionella pneumonia in human immunodeficiency virus (HIV)-infected patients were comparable to those seen in non-HIV-infected patients (case-control design). ...

Development of cutaneous toxicities during selective anti-BRAF therapies: preventive role of combination with MEK inhibitors 

Erfan, Gamze; Puig i Sardà, Susana; Carrera Álvarez, Cristina; Arance, Ana; Gaba, Lydia; García Herrera, Adriana; Alós i Hernández, Llúcia; Malvehy, J. (Josep) (Publication date: 2018-02-14)

Activated BRAF mutations affecting the mitogen-activated protein kinases (MAPK) pathway are present in 50% of metastatic melanomas. Targeted therapies have been developed to block such mutations (1, 2). There is a risk of ...

New insights into the role of macrophages in adipose tissue inflammation and fatty liver disease: modulation by endogenous omega-3 fatty acid-derived lipid mediators 

Clària i Enrich, Joan; González Périz, Ana; López Vicario, Cristina; Rius, Bibiana; Titos Rodríguez, Esther (Publication date: 2019-08-01)

Obesity is causally linked to a chronic state of 'low-grade' inflammation in adipose tissue. Prolonged, unremitting inflammation in this tissue has a direct impact on insulin-sensitive tissues (i.e., liver) and its timely ...

Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis 

Queck, Alexander; Thomas, Dominique; Jansen, Christian; Schreiber, Yannick; Rüschenbaum, Sabrina; Praktiknjo, Michael; Schwarzkopf, Katharina Maria; Mücke, Marcus Maximilian; Schierwagen, Robert; Uschner, Frank Erhard; Meyer, Carsten; Clària i Enrich, Joan; Zeuzem, Stefan; Geisslinger, Gerd; Trebicka, Jonel; Lange, Christian Markus (Publication date: 2020-04-27)

BACKGROUND: Prostanoids are important regulators of platelet aggregation and thrombotic arterial diseases. Their involvement in the development of portal vein thrombosis, frequent in decompensated liver cirrhosis, is still ...

Cost-effectiveness of a technology-supported multimodal prehabilitation program in moderate-to-high risk patients undergoing lung cancer resection: randomized controlled trial protocol 

Barberán García, Anael; Navarro Ripoll, Ricard; Sánchez Lorente, David; Moisés, Jorge; Boada, Marc; Messaggi Sartor, Monique; González Vallespí, Laura; Montane Muntane, Mar; Alsina Restoy, Xavier; Campero, Betina; López Baamonde, Manuel; Romano Andrioni, Bárbara; Guzmán Portillo, Rudith; López, Antonio; Arguis Giménez, María José; Roca Torrent, Josep; Martínez Palli, Graciela (Publication date: 2021-05-06)

Background: Multimodal prehabilitation is a preoperative intervention with the objective to enhance cancer patients' functional status which has been showed to reduce both postoperative morbidity and hospital length of ...

Dietary Iron, Anemia Markers, Cognition, and Quality of Life in Older Community-Dwelling Subjects at High Cardiovascular Risk 

Ruiz Canela, Miguel; Babio, Nancy; Martínez, J. Alfredo; Donat Vargas, Carolina; Micó, Víctor; San Cristobal, Rodrigo; Martínez-González, Miguel Ángel, 1957-; Salas Salvadó, Jordi; Corella Piquer, Dolores; Fitó Colomer, Montserrat; Alonso Gómez, Ángel M.; Wärnberg, Julia; Vioque, Jesús; Romaguera, Dora; López Miranda, José; Estruch Riba, Ramon; Damas-Fuentes, Miguel; Lapetra, José; Serra Majem, Lluís; Bueno Cavanillas, Aurora; Tur, Josep Antoni; Cinza Sanjurjo, Sergio; Pintó Sala, Xavier; Delgado Rodríguez, Miguel; Matía Martín, Pilar; Vidal, Josep; Causso, Claudia; Ros Rahola, Emilio; Toledo Atucha, Estefanía; Manzanares, J.M.; Ortega Azorín, Carolina; Castañer, Olga; Peña Orihuela, Patricia J.; Zazo, Juan Manuel; Muñoz Bravo, Carlos; Martinez Urbistondo, Diego; Chaplin, Alice; Casas Rodríguez, Rosa M.; Cano Ibáñez, Naomi; Tojal Sierra, Lucas; Gómez Pérez, Ana María; Pascual Roquet Jalmar, Elena; Mestre, Cristina; Barragán, Rocío; Schröder, Helmut, 1958-; García Ríos, Antonio; Candela García, Inma; Malcampo, Mireia; Daimiel, Lidia (Publication date: 2024-01-31)

Anemia causes hypo-oxygenation in the brain, which could lead to cognitive disorders. We examined dietary iron intake as well as anemia markers (i.e., hemoglobin, hematocrit, mean corpuscular volume) and diabetes coexistence ...

Effects of polyphenol, measured by a biomarker of total polyphenols in urine, on cardiovascular risk factors after a long-term follow-up in the PREDIMED study 

Guo, Xiaohui; Tresserra i Rimbau, Anna; Estruch Riba, Ramon; Martínez-González, Miguel Ángel, 1957-; Medina Remón, Alexander; Castañer, Olga; Corella Piquer, Dolores; Salas Salvadó, Jordi; Lamuela Raventós, Rosa Ma. (Publication date: 2018-01-10)

Several epidemiological studies have shown an inverse association between the consumption of polyphenol-rich foods and risk of cardiovascular diseases. However, accuracy and reliability of these studies may be increased ...

Time to Diagnosis and Presenting Symptoms of Patients Diagnosed With Cancer Through Emergency and Nonemergency Routes: A Large Retrospective Study From a High-Volume Center 

Bosch Genover, Xavier; Mota Gomes, Tiago; Montori Palacín, Elisabet; Moreno Lozano, Pedro Juan; López-Soto, Alfonso (Publication date: 2026-02-27)

Purpose The symptoms with which a patient with cancer presents and the route taken to diagnosis (emergency v nonemergency) may affect the speed with which the diagnosis of cancer is made, thereby affecting outcomes. We ...

Quantitative evaluation of trunk function and the StartReact effect during reaching in patients with cervical and thoracic spinal cord injury 

Castillo Escario, Yolanda; Kumru, Hatice; Valls Solé, Josep; García Alen, Loreto; Jané, Raimon; Vidal Samsó, Joan (Publication date: 2021-10-26)

Reproducció del document publicat a: https://doi.org/10.1088/1741-2552/ac19d3

Differences and Similarities between the Lung Transcriptomic Profiles of COVID-19, COPD, and IPF Patients: A Meta-Analysis Study of Pathophysiological Signaling Pathways 

Aguilar, Daniel; Bosacoma, Adelaida; Blanco Vich, Isabel; Tura-Ceide, Olga; Serrano Mollar, Anna; Barberà i Mir, Joan Albert; Peinado Cabré, Víctor Ivo (Publication date: 2023-06-21)

Coronavirus disease 2019 (COVID-19) is a pandemic respiratory disease associated with high morbidity and mortality. Although many patients recover, long-term sequelae after infection have become increasingly recognized and ...

State-dependent skin temperature increase during manic episodes of bipolar disorder 

Valenzuela-Pascual, Clàudia; Lamberti, Rocío G.; Mas, Ariadna; Borràs, Roger; Anmella, Gerard; Corponi, Filippo; Oliva, Vincenzo; De Prisco, Michele; Korniyenko, Marta; Garriga, Marina; González Campos, Meritxell; Valentí Ribas, Marc; Pacchiarotti, Isabella; Benabarre, Antonio; Grande i Fullana, Iria; Bastidas Salvadó, Anna; Agasi, Isabel; Romero López-Alberca, Cristina; Muñoz Doña, Cecilia; Catalán, Ana; Young, Allan H.; Berk, Michael; Vieta i Pascual, Eduard, 1963-; Hidalgo Mazzei, Diego (Publication date: 2025-06-25)

Skin temperature changes during mood episodes and can be continuously monitored through wearable devices, potentially serving as a digital biomarker. We aimed to describe differences in skin temperature among bipolar ...

Brain cortical maturation assessed by magnetic resonance imaging in unaffected/mildly affected fetuses with cytomegalovirus infection 

Hawkins Villarreal, Ameth; Moreno Espinosa, Ana L.; Castillo, Karen; Hahner, Nadine; Picone, Olivier; Mandelbrot, Laurent; Simon, Isabelle; Gratacós Solsona, Eduard; Goncé Mellgren, Anna; Eixarch Roca, Elisenda (Publication date: 2024-11-08)

Objectives: To assess by magnetic resonance imaging (MRI) the cortical maturation pattern in fetuses with cytomegalovirus (CMV) infection with mild or no abnormalities on ultrasound (US) and MRI, and to establish possible ...

Blocking Placental Class G Immunoglobulin Transfer Prevents NMDA Receptor Antibody Effects in Newborn Mice 

García Serra, Anna; Radosevic, Marija; Ríos, José; Aguilar, Esther; Maudes, Estibaliz; Landa Medrano, Jon; Sabater Baudet, Lidia; Martínez Hernández, Eugenia; Planagumà, Jaume; Dalmau Obrador, Josep (Publication date: 2022-01-27)

To determine in a mouse model whether neonatal Fc receptor (FcRn) blockade prevents the placental transfer of class G immunoglobulin (IgG) derived from patients with anti-NMDA receptor (NMDAR) encephalitis and their ...