Mostrando ítems 1-20 de 627

    Emotional intelligence and neurocognition profiles in first-episode psychosis: A two-year follow-up study 

    Clougher, Derek; Forte, Maria Florencia; Mezquida Mateos, Gisela; Sánchez Torres, Ana M.; Serra Navarro, Maria; Penadés Rubio, Rafael; Lobo, Antonio; González-Pinto, Ana; Panadero Gómez, Rocío; Roldán, Alexandra; Vieta i Pascual, Eduard, 1963-; Serna, Elena de la, 1978-; Trabsa, Amira; Martínez-Arán, Anabel, 1971-; Torrent Font, Carla; Tortorella, Alfonso; Menculini, Giulia; Ramos-Quiroga, Josep Antoni; Cuesta, Manuel J.; Bernardo Arroyo, Miquel; Amoretti Guadall, Silvia; PEPs Group (Fecha de publicación: 2025-10-09)

    Emotional intelligence (EI) and neurocognition (NC) impairments are common in first-episode psychosis (FEP), yet their evolution over time remains unclear. This study identified patient profiles in EI and NC performance ...

    Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia 

    Gimenez, Neus; Tripathi, Rupal; Giró, Ariadna; Rosich, Laia; López Guerra, Mónica; López Oreja, Irene; Playa-Albinyana, Heribert; Arenas Ríos, Fabián; Mas, José Manuel; Pérez Galán, Patricia; Delgado, Julio (Delgado González); Campo Güerri, Elias; Farrés, Judith; Colomer Pujol, Dolors (Fecha de publicación: 2025-10-23)

    Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. Despite new targeted therapies such as ibrutinib and venetoclax, disease progression and relapse remain an issue. CLL ...

    Challenges with Approved Targeted Therapies against Recurrent Mutations in CLL: A Place for New Actionable Targets 

    López Oreja, Irene; Playa-Albinyana, Heribert; Arenas Ríos, Fabián; López Guerra, Mónica; Colomer Pujol, Dolors (Fecha de publicación: 2025-09-26)

    Chronic lymphocytic leukemia (CLL) is characterized by a high degree of genetic variability and interpatient heterogeneity. In the last decade, novel alterations have been described. Some of them impact on the prognosis ...

    SF3B1 mutation-mediated sensitization to H3B-8800 splicing inhibitor in chronic lymphocytic leukemia 

    López Oreja, Irene; Gohr, Andre; Playa-Albinyana, Heribert; Giró, Ariadna; Arenas Ríos, Fabián; Higashi, Morihiro; Tripathi, Rupal; López Guerra, Mónica; Irimia Martínez, Manuel; Aymerich Gregorio, Marta; Valcárcel Juárez, Juan; Bonnal, Sophie; Colomer Pujol, Dolors (Fecha de publicación: 2025-11-12)

    Splicing factor 3B subunit 1 (SF3B1) is involved in pre-mRNA branch site recognition and is the target of antitumor-splicing inhibitors. Mutations in SF3B1 are observed in 15% of patients with chronic lymphocytic leukemia ...

    Imaging Efficacy of [18F]CTT1057 PET/CT in Patients with Biochemically Recurrent Prostate Cancer: Results from GuidePath-A Phase 3, Prospective Multicenter Study 

    Fanti, Stefano; Robles Barba, Javier Jesus; Behr, Spencer; Maurer, Tobias; Paredes Barranco, Pilar; Walz, Jochen; Duch, Joan; Simo Perdigo, Marc; Mainta, Ismini Charis; Bonnefoy, Pierre Benoit; Coulanges, Medge; Tang, Jun; Seigne, Christelle; Wilke, Celine; Catafau, Ana M.; Iagaru, Andrei; Aggarwal, Rahul (Fecha de publicación: 2025-09-25)

    Improved diagnostic accuracy in patients with prostate cancer at first biochemical recurrence (BCR) with low prostate-specific antigen (PSA) levels is needed. This prospective study (GuidePath; NCT04838613) aimed to evaluate ...

    A low total metabolic tumor volume independently predicts for a longer time to first treatment in initially observed, low tumor burden follicular lymphoma 

    Mozas, Pablo; Casanueva Eliceiry, Sebastián; Rivero, Andrea; Serna, Ángel; Simó, Marc; Rodríguez, Sonia; Rivas Delgado, Alfredo; Nadeu, Ferran; Correa, Juan Gonzalo; Piñeyroa, Juan Antonio; Pérez-Valencia, Amanda Isabel; Guinetti-Ortiz, Katia; Gómez-Hernando, Marta; Giné, Eva; Delgado, Julio; Villamor i Casas, Neus; Campo, Elías; Magnano, Laura; Abrisqueta Costa, Pau; Setoain Perego, Xavier; López-Guillermo, Aramando (Fecha de publicación: 2025-01-23)

    Watchful waiting is an acceptable management strategy for advanced-stage, low tumor burden (LTB) patients with follicular lymphoma (FL). However, the prediction of how long this treatment-free observation period will last ...

    Diagnóstico prequirúrgico de gliomas difusos en adultos: perspectivas prácticas de radiólogos de Unidades de neurooncología Post-WHO 2021 

    Pons Escoda, Albert; Majós Torró, Carlos; Smits, Marion; Oleaga Zufiría, Laura (Fecha de publicación: 2024-08-30)

    La Clasificación 2021 de tumores del sistema nervioso central (SNC) por la Organización Mundial de la Salud (OMS) fue acogida con entusiasmo, aunque al principio pudo parecer abrumadora. Con el tiempo, hemos comprendido ...

    Dissemination of NDM-producing Klebsiella pneumoniae and Escherichia coli high-risk clones in Catalan healthcare institutions 

    Marí Almirall, Marta; Cosgaya Castro, Clara; Pitart, Cristina; Viñes, Joaquim; Muñoz López, Laura; Campo, Irene; Cuscó, Anna; Rodríguez Serna, Laura; Santana, Gemina; Río, Ana del; Francino, Olga; Ciruela, Pilar; Pujol, Isabel; Ballester, Frederic; Marco, Francesc; Martínez Hernández, José Alfredo; Soriano Viladomiu, Alex; Vila Estapé, Jordi; Roca Subirà, Ignasi; MERCyCAT Study Group (Fecha de publicación: 2023-12-11)

    Objectives: To characterize the clonal spread of carbapenem-resistant Klebsiella pneumoniae and Escherichia coli isolates between different healthcare institutions in Catalonia, Spain. Methods: Antimicrobial susceptibility ...

    Halo sign in fetal cytomegalovirus infection: cerebral imaging abnormalities and postmortem histopathology in cohort of 35 infected fetuses. 

    Hawkins-Villarreal, Ameth; Castillo, Karen; Nadal Serra, Alfons; Planas i Marcé, Sílvia, 1965-; Moreno Espinosa, Ana L.; Alarcón, Ana; Rebollo Polo, Mónica; Figueras Retuerta, Francesc; Gratacós Solsona, Eduard; Eixarch Roca, Elisenda; Goncé Mellgren, Anna (Fecha de publicación: 2024-02-05)

    To evaluate the correlation of periventricular echogenic halo (halo sign) with histopathological findings and its association with other brain imaging abnormalities in fetuses with cytomegalovirus (CMV) infection.

    Genotypic and phenotypic study of antiviral resistance mutations in refractory cytomegalovirus infection 

    Santos Bravo, Marta; Nicolas Plault; Sánchez Palomino, Sonsoles; Rodríguez, Cristina; Navarro Gabriel, Mireia; Mosquera, María Mar; Fernández Avilés, Francesc; Suarez Lledó, María; Rovira, Montserrat; Bodro, Marta; Moreno Camacho, Ma. Asunción; Linares, Laura; Cofán Pujol, Federico; Berengua, Carla; Esteva, Cristina; Cordero, Elisa; Martín Dávila, Pilar; Aranzamendi, Maitane; Pérez Jiménez, Ana Belén; Vidal, Elisa; Fernández Sabé, Núria; Len, Óscar; Hantz, Sebastien; Alain, Sophie; Marcos, Ma. Angeles; the Spanish Network for Research in Infectious Diseases (REIPI); Group for the Study of Infection in Transplantation (GESITRA) (Fecha de publicación: 2023-12-04)

    Background This study describes the genotypic and phenotypic characterization of novel human cytomegalovirus (HCMV) genetic variants of a cohort of 94 clinically resistant HCMV patients. Methods and results ...

    Ultrasensitive multiplex optical quantification of bacteria in large samples of biofluids 

    Pazos Pérez, Nicolas; Pazos, Elena; Catala, Carme; Mir Simon, Bernat; Gómez de Pedro, Sara; Sagales, Juan; Villanueva, Carlos; Vila Estapé, Jordi; Soriano Viladomiu, Alex; García de Abajo, F. Javier; Álvarez Puebla, Ramón A. (Fecha de publicación: 2016-09-06)

    Efficient treatments in bacterial infections require the fast and accurate recognition of pathogens, with concentrations as low as one per milliliter in the case of septicemia. Detecting ...

    The many faces of small B cell lymphomas with plasmacytic differentiation and the contribution of MYD88 testing 

    Swerdlow, Steven H.; Kuzu, Isinsu; Dogan, Ahmet; Dirnhofer, Stephan; Chan, John K. C.; Sander, Birgitta; Ott, German; Xerri, Luc; Quintanilla Martinez, Leticia; Campo Güerri, Elias (Fecha de publicación: 2019-02-11)

    Plasmacytic differentiation may occur in almost all small B cell lymphomas (SBLs), although it varies from being uniformly present (as in lymphoplasmacytic lymphoma (LPL)) to very uncommon (as in mantle cell lymphomas ...

    L'Intrusisme professional a principis del segle XX. El Dr. James M. Munyon. 

    Torres, Begoña; Sabaté i Casellas, Ferran (Fecha de publicación: 2015-01-28)

    RESUM: Presentem al Dr. James M. Munyon, qui a principis del segle passat es dedicà a la manufactura i patent de remeis homeopàtics. Va ser perseguit per frau en múltiples ocasions però la seva gran fortuna li va permetre ...

    Biofilm Formation in Uropathogenic Escherichia coli Strains: Relationship with Urovirulence Factors and Antimicrobial Resistance 

    Soto González, Sara M.; Marco, Francesc; Guiral Vilalta, Elisabet; Vila Estapé, Jordi (Fecha de publicación: 2021-03-05)

    Evidence of activation of the Toll-like receptor-4 proinflammatory pathway in patients with schizophrenia 

    García Bueno, Borja; Gassó Astorga, Patricia; MacDowell, Karina S.; Callado, Luis F.; Mas Herrero, Sergi; Bernardo Arroyo, Miquel; Lafuente, Amàlia, 1952-2022; Meana, J. Javier; Leza, Juan Carlos (Fecha de publicación: 2018-01-12)

    BACKGROUND: Alterations in the innate immune/inflammatory system may underlie the pathophysiology of schizophrenia, but we do not understand the mechanisms involved. The main agents of innate immunity are the Toll-like ...

    Genotypic and phenotypic study of antiviral resistance mutations in refractory cytomegalovirus infection 

    Santos Bravo, Marta; Nicolas Plault; Sánchez-Palomino, Sonsoles; Rodríguez, Cristina; Navarro Gabriel, Mireia; Mosquera, María Mar; Fernández Avilés, Francesc; Suárez-Lledó Grande, María; Rovira, Montserrat; Bodro, Marta; Moreno Camacho, Ma. Asunción; Linares, Laura; Cofán Pujol, Federico; Berengua, Carla; Esteva, Cristina; Cordero, Elisa; Martín Dávila, Pilar; Aranzamendi, Maitane; Pérez Jiménez, Ana Belén; Vidal, Elisa; Fernández Sabé, Núria; Len, Óscar; Hantz, Sebastien; Alain, Sophie; Marcos, Ma. Angeles; Spanish Network for Research in Infectious Diseases (REIPI); Group for the Study of Infection in Transplantation (GESITRA) (Fecha de publicación: 2023-12-05)

    Background This study describes the genotypic and phenotypic characterization of novel human cytomegalovirus (HCMV) genetic variants of a cohort of 94 clinically resistant HCMV patients. Methods and results ...

    Review of the Microbiological Diagnostic Approaches of COVID-19 

    Melo Vallès, Ada; Ballesté Delpierre, Clara Celia; Vila Estapé, Jordi (Fecha de publicación: 2023-03-15)

    On March 12, the World Health Organization declared a pandemic following the exponential increase of SARS-CoV-2 cases. The rapid spread of the virus is due to both its high infectivity and the free circulation of unrecognized ...

    Transposon insertion in the purL gene induces biofilm depletion in Escherichia coli ATCC 25922 

    Cepas, Virginio; Ballén, Victoria; Gabasa, Yaiza; Ramírez, Miriam; López, Yuly; Soto González, Sara M. (Fecha de publicación: 2021-04-19)

    Current Escherichia coli antibiofilm treatments comprise a combination of antibiotics commonly used against planktonic cells, leading to treatment failure. A better understanding of the genes involved in biofilm formation ...

    Exosome analysis in tumor-draining pulmonary vein identifies NSCLC patients with higher risk of relapse after curative surgery 

    Navarro Ponz, Alfons; Molins López-Rodó, Laureano; Marrades Sicart, Ramon Ma.; Moisés, Jorge; Viñolas Segarra, Núria; Morales, Sara; Canals, Jordi; Castellano, Joan Josep; Ramirez, José; Monzó Planella, Mariano (Fecha de publicación: 2019-03-04)

    Since tumor-draining pulmonary vein blood (PV) is enriched in tumor-secreted products, we hypothesized that it would also be enriched in tumor-derived exosomes, which would be important in the metastasis process. We ...

    Integrating genetic, neuropsychological and neuroimaging data to model early-onset obsessive compulsive disorder severity 

    Mas Herrero, Sergi; Gassó Astorga, Patricia; Morer Liñán, Astrid; Calvo, Anna; Bargalló Alabart, Núria; Lafuente, Amàlia, 1952-2022; Lázaro García, Luisa (Fecha de publicación: 2016-12-09)

    We propose an integrative approach that combines structural magnetic resonance imaging data (MRI), diffusion tensor imaging data (DTI), neuropsychological data, and genetic data to predict early-onset obsessive compulsive ...