Bioquímica i Fisiologia

Logo universitat

Els materials de recerca de la Universitat de Barcelona (UB) a RECERCAT s'obtenen de les col·leccions de Recerca del Dipòsit Digital de la UB.
Si sou membre de la UB i esteu interessat a publicar materials de recerca contacteu amb dipositdigital@ub.edu o consulteu les indicacions .

Política d’accés obert a la UB


Publicacions en accés obert derivades de l'activitat investigadora del professorat de la Universitat de Barcelona.

Enviaments recents

Llista ítems afegits recenment

Is There a Future Without Gluten Restrictions for Celiac Patients? Update on Current Treatments. 

Girbal-González, Marina; Pérez-Cano, Francisco J. (Data de publicació: 2026-02-27)

Celiac disease (CeD) is a chronic autoimmune enteropathy triggered by dietary gluten in genetically predisposed individuals. Along with other disorders such as non-celiac gluten/wheat sensitivity and gluten allergy, adherence ...

<u>Evaluation of Ultra-High Pressure Homogenization Treatments to Ensure the Microbiological Safety and Immunoglobulin Preservation in Donor Human Milk.</u>J 

Hernández-Herrero, M. Manuela; Jalali, Kimia; Pastor-Villaescusa, Belén; Flores-Rojas, Katherine; Pleguezuelos, Vanessa; Pérez-Cano, Francisco J.; Franch i Masferrer, Àngels; Trujillo-Mesa, Antonio J.; Roig-Sagués, Artur X. (Data de publicació: 2026-02-27)

Most donor human milk (HM) banks use Holder pasteurization (HoP) to ensure microbiological safety, although it can degrade essential bioactive factors for newborns. This study evaluates the innovative ultra-high-pressure ...

Cocoa Supplementation Alleviates Gliadin-Induced Intestinal Dysbiosis in a Mouse Model of Celiac Disease 

Girbal, Marina; Rodríguez Lagunas, María José; Rodríguez-Banqueri, Arturo; Eckhard, Ulrich; Gomis Rüth, F. Xavier; Franch, Aina; Pérez-Cano, Francisco J. (Data de publicació: 2026-02-27)

Celiac disease (CeD) is a chronic immune-mediated enteropathy triggered by dietary gluten in genetically predisposed individuals which also entails intestinal dysbiosis. This hallmark microbial imbalance provides a rationale ...

Editorial: Immunonutrition: bridging precision nutrition and modern medicine. 

Almeida, Jani; Sá, Helena; Pérez-Cano, Francisco J.; Viana, Sofia (Data de publicació: 2026-02-27)

Inflammation imposes substantial metabolic demands and depletes critical nutrient reserves, often impairing immune function. While adequate nutrition is foundational to immune homeostasis, the targeted use of supraphysiological ...

Novel nanostructured lipid carriers loading Apigenin for anterior segment ocular pathologies 

Bonilla-Vidal, L; Espina García, Marta; García López, María Luisa; Baldomà Llavinés, Laura; Badía Palacín, Josefa; González Sánchez, Jose Antonio; Delgado, Luís María; Gliszczyńska, Anna; Souto, Eliana B.; Sánchez-López, E. (Elena) (Data de publicació: 2026-02-25)

Dry eye disease (DED) is a chronic multifactorial disorder of the ocular surface caused by tear film dysfunction and constitutes one of the most common ocular conditions worldwide. However, its treatment remains unsatisfactory. ...

Maternal diet shapes infant microbiota and defensive capacity against infections in early life via differential human milk composition 

Rio Aige, Karla; Selma-Royo, Marta; Cabrera-Rubio, Raúl; Gonzalez, Sergi; Martínez Costa, Cecilia; Castell, Margarida; Rodríguez Lagunas, María José; Collado, Maria Carmen; Pérez-Cano, Francisco J. (Data de publicació: 2026-02-06)

Maternal nutritional status and dietary profile during pregnancy and lactation have short- and long-term impacts on offspring health. However, there is an incomplete understanding of the mechanisms behind these health ...

Lighting conditions during suckling modify rat pupillary light responses but not entrainment to 24-hour sawtooth dim light-dark cycles 

Cambras Riu, Trinitat; Díez Noguera, Antoni (Data de publicació: 2026-01-26)

Early-life experiences have lasting consequences on future health. This study examined the impact of bright light exposure during suckling on non-image-forming system responses, specifically the pupillary light reflex (PLR) ...

Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-Deoxy-D-Xylulose 5-phosphate reductoisomerase, the first commited enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway. 

Carretero Paulet, Lorenzo; Ahumada, Iván; Cunillera i Segarra, Núria; Rodríguez Concepción, Manuel; Ferrer i Prats, Albert; Boronat i Margosa, Albert; Campos Martínez, Narciso (Data de publicació: 2026-01-21)

1-Deoxy-d-xylulose 5-phosphate reductoisomerase (DXR) catalyzes the first committed step of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. In Arabidopsis, DXR is encoded by a single-copy gene. ...

Mirabegron induces selective changes in the faecal microbiota of HFHFr rats without altering bile acid composition 

Bentanachs Raset, Roger; Miró Martí, Ma. Lluïsa; Ramírez-Carrasco, Patricia; Sánchez, Rosa María; Bernabeu Lorenzo, Manuel; Amat, Concepció; Alegret i Jordà, Marta; Pérez Bosque, Anna; Roglans i Ribas, Núria; Laguna Egea, Juan Carlos (Data de publicació: 2026-01-16)

In the present work, we analyse stored liver, adipose tissue (perigonadal</p><p>and brown), serum and faecal samples from our previous study and present new</p><p>biochemical, faecal metabolomic and microbiome data.</p><p>We ...

Arabidopsis thaliana contains two differentially expressed 3-hydroxy-3-methylglutaryl-CoA reductase genes, wich encode microsomal forms of the enzyme 

Enjuto, Montserrat; Balcells i Argemí, Lluís; Campos Martínez, Narciso; Caelles Franch, Carme; Arró i Plans, Montserrat; Boronat i Margosa, Albert (Data de publicació: 2026-01-16)

The enzyme 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR; EC 1.1.1.34) catalyzes the first rate-limiting step in plant isoprenoid biosynthesis. Arabidopsis thaliana contains two genes, HMG1 and HMG2, that encode HMGR. We ...

GPR88 impairs the signaling of kappa opioid receptors in a heterologous system and in primary striatal neurons 

Rivas‐Santisteban, Rafael; Lillo, Jaume; Garrigós, Claudia; Navarro Brugal, Gemma; Franco Fernández, Rafael (Data de publicació: 2025-12-10)

The physiological role of GPR88, an orphan G protein-coupled receptor (GPCR) predominantly expressed in the striatum, remains unclear, despite its altered expression in parkinsonian animal models. GPR88 is known to interact ...

Inhibition of PCSK9 with polypurine reverse hoogsteen hairpins: A novel gene therapy approach 

López-Aguilar, Ester; Pacheco-Velázquez, Silvia Cecilia; Busquets i Viñas, Ma. Antonia; Hay, J.oshua; Mueller, P.aul A.; Fazio, Sergio; Ciudad i Gómez, Carlos Julián; Noé Mata, Verónica; Pamir, Nathalie (Data de publicació: 2025-10-22)

PCSK9 is a therapeutic target for hypercholesterolemia. Though different strategies to inhibit PCSK9, such as monoclonal antibodies, small molecules, or nucleic acid drugs are available, the need for safer and inexpensive ...

Assessment of Flurbiprofen Suspension and Composite GelPre- and Post Skin Perforation: Effectiveness in ManagingInflammatory Responses in Ear Tags and Periocular Piercings. 

El Bejjaji, Sheimah; Ramos Yacasi, Gladys Rosario; Domínguez Villegas, Valeri; Chaves Moreira Dos Santos, Délia; Braza Reyes, Antonio J.; Sosa Díaz, Lilian Elisa; Rodríguez Lagunas, María José; Calpena Campmany, Ana Cristina; Zelaya, Mireia; Parra Coca, Alexander (Data de publicació: 2025-07-17)

Background: Controlled skin perforations, such as ear tags, piercings, and microdermal implants, induce inflammation and stress in individuals undergoing these procedures. This localized trauma requires care to optimize ...

Developing a global education hub for animal-free innovation 

Janssens, Monique R. E.; Salvatori, Daniela; Hogervorst, Janneke; Nonis, Cristheena; Bailey, Jarrod; Bajramovic, Jeffrey; Burgers, Anne; Caloni, Francesca; van Deel, Elza D.; van den Eijnden-van Raaij, Janny; Amirabadi, Hossein E.; Filipova, Dilyana; Gastaldello, Annalisa; Gibbs, Susan; Goversen, Birgit; Green, Nicole; van Hengel, Jolanda; Kienhuis, Anne; van de Kolk, Sjoukje; Paggi, Carlo A.; Penning, Louis C.; Pistollato, Francesca; Riegger, Silke; Ritskes-Hoitinga, Merel; Vinardell Martínez-Hidalgo, Ma. Pilar (Data de publicació: 2025-06-23)

In recent decades, the life sciences have witnessed remarkable advancements, leading to breakthroughs in medicine, agriculture, and environmental science. Although experiments on animals have been used ...

Mendelian Randomization Analysis of the Relationship Between Native American Ancestry and Gallbladder Cancer Risk 

Zollner, Linda; Boekstegers, Felix; Barahona Ponce, Carol; Scherer, Dominique; Marcelain, Katherine; Gárate-Calderón, Valentina; Waldenberger, Melanie; Morales, Erik; Rojas, Armando; Muñoz, Cesar; Müller, Bettina; Retamales, Javier; de Toro, Gonzalo; Kortmann, Allan Vera; Barajas, Olga; Rivera, María Teresa; Cortés, Analía; Loader, Denisse; Saavedra, Javiera; Gutiérrez, Lorena; Ortega, Alejandro; Bertrán, Maria Enriqueta; Bartolotti, Leonardo; Gabler, Fernando; Campos, Mónica; Alvarado, Juan; Moisán, Fabrizio; Spencer, Loreto; Nervi, Bruno; Carvajal-Hausdorf, Daniel E.; Losada, Héctor; Almau, Mauricio; Fernández, Plinio; Olloquequi, Jordi; Carter, Alice R.; Miquel Poblete, Juan Francisco; Bustos, Bernabe I.; Fuentes-Guajardo, Macarena; Gonzalez-Jose, Rolando; Bortolini, M. C.; Acuña-Alonzo, Víctor; Gallo, Carla; Ruiz Linares, Andres; Rothhammer, Francisco; Lorenzo Bermejo, Justo (Data de publicació: 2023-12-22)

Background A strong association between the proportion of Native American ancestry and the risk of gallbladder cancer (GBC) has been reported in observational studies. Chileans show the highest incidence of GBC worldwide, ...

Mendelian Randomization Analysis of the Relationship Between Native American Ancestry and Gallbladder Cancer Risk 

Zollner, Linda; Boekstegers, Felix; Barahona Ponce, Carol; Scherer, Dominique; Marcelain, Katherine; Gárate-Calderón, Valentina; Waldenberger, Melanie; Morales, Erik; Rojas, Armando; Muñoz, Cesar; Müller, Bettina; Retamales, Javier; de Toro, Gonzalo; Kortmann, Allan Vera; Barajas, Olga; Rivera, María Teresa; Cortés, Analía; Loader, Denisse; Saavedra, Javiera; Gutiérrez, Lorena; Ortega, Alejandro; Bertrán, Maria Enriqueta; Bartolotti, Leonardo; Gabler, Fernando; Campos, Mónica; Alvarado, Juan; Moisán, Fabrizio; Spencer, Loreto; Nervi, Bruno; Carvajal-Hausdorf, Daniel E.; Losada, Héctor; Almau, Mauricio; Fernández, Plinio; Olloquequi, Jordi; Carter, Alice R.; Miquel Poblete, Juan Francisco; Bustos, Bernabe I.; Fuentes-Guajardo, Macarena; Gonzalez-Jose, Rolando; Bortolini, M. C.; Acuña-Alonzo, Víctor; Gallo, Carla; Ruiz Linares, Andres; Rothhammer, Francisco; Lorenzo Bermejo, Justo (Data de publicació: 2024-01-17)

Background A strong association between the proportion of Native American ancestry and the risk of gallbladder cancer (GBC) has been reported in observational studies. Chileans show the highest incidence of GBC worldwide, ...

Compartir ideas. La Universidad va al Instituto: un proyecto de aprendizaje- servicio transversal de la Universidad de Barcelona 

Amat, Concepció; Anderson, Miriam; Arias Sampériz, Bárbara; Asensio, José Antonio, 1957-; Ballesteros Pérez, Esperanza; Boix, Emili, 1956-; Bondia, David; Buenaventura Rubio, Maria Antonia; Bueno i Torrens, David, 1965-; Carrera i Sabaté, Josefina; Cases Rodrigo, Irene; Coll, Tónia, 1965-; Collado Sevilla, Antonia; Condom Bosch, Josep Lluís; Cortès Izquierdo, Ferran; Costa Cuberta, Mercè; Cuffí i Chéliz, Maria Laura; Delás, Jordi; Domingo, Josep M. (Domingo Clua); Escobedo, Anna; Escofet Roig, Anna; Esparza Pagès, Mireia; Esteban i Torné, Maria Esther; Fatjó-Vilas Mestre, Mar; Fernández Cuevas, Ana Belén; Fontiveros Sánchez, Manuel; García García, Ascensión; Giménez Merino, Antonio; Goula, Marta; Grasso, Guillermo; Grau, Eulàlia (Grau i Costa); Illán Villanueva, Montserrat; Lama López, María Xesús; Lecuona Ramírez, Itziar de; López, Marta; Madrid, Antonio, 1968-; March Pujol, Marian; Martín García, Ma. Jesús; Martínez Martín, Miquel; Massip i Bonet, M. Àngels, 1957- (Data de publicació: 2021-06-03)

Compartir ideas. La universidad va al instituto es un proyecto de aprendizaje servicio transversal de la Universidad de Barcelona. Este representa una propuesta de aprendizaje servicio que bajo una estructura común permite ...

Creation and Implementation of a New Sentinel Surveillance Model in Pharmacy Offices in Southern Europe 

Jambrina Albiach, Anna Maria; Rams, Neus; Rius, Pilar; Perelló, Maria; Gironès, Montserrat; Pareja, Clara; Pérez-Cano, Francisco J.; Franch i Masferrer, Àngels; Rabanal i Tornero, Manel (Data de publicació: 2023-02-24)

Traditionally, health sentinel networks have focused on the reporting of data by primary care physicians and hospitals, ignoring the role of the community pharmacist as an expert in drugs. The objective of this study was ...

Effect of a cocoa flavonoid-enriched diet on experimental autoimmune arthritis 

Ramos Romero, Sara; Pérez-Cano, Francisco J.; Pérez Berezo, Teresa; Castellote i Bargalló, M. Cristina; Franch i Masferrer, Àngels; Castell, Margarida (Data de publicació: 2012-12-03)

Previously we established that a cocoa-enriched diet in young rats reduces the specific antibody production and the Th lymphocyte proportion in lymphoid tissues. The aim of the present study was to ascertain the modulatory ...

Photoprotective potential of emulsions formulated with Buriti oil (Mauritia flexuosa) and Vitamin E against UV irradiation on human keratinocytes and fibroblasts cell lines 

Zanatta, C. F.; Mitjans Arnal, Montserrat; Ugartondo Casadevall, Vanessa; Rocha-Filho, P. A.; Vinardell Martínez-Hidalgo, Ma. Pilar (Data de publicació: 2012-10-31)

Considering the belief that natural lipids and edible substances are safer for topical applications and that carotenoids are able to protect cells against photooxidative damage, wea have investigated whether topical creams ...

Més