Biomedicina: Envíos recientes
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Palmitoylcarnitine impairs immunity in decompensated cirrhosis
Background & aims: In patients with cirrhosis, acute decompensation (AD) correlates with a hyperinflammatory state driven by mitochondrial dysfunction, which is a significant factor in the progression toward acute-on-chronic ...
Andronet News. Spring 2023
Our main annual event is quickly approaching - we are looking forward to the ANDRONET Workshop and the Managing Committee Meeting which will be held in June in conjunction with the 22nd European Testis Workshop (ETW2023), ...
Andronet News. Autumn 2023
The second year of the Action has passed at the end of October 2023. I am happy to inform you that at the start of the third grant period we have a very good number of members - 291 from 42 countries, including 37 COST ...
Andronet News. Winter 2024-2025
This newsletter marks the beginning of the last year of our COST ANDRONET Action. That does not mean that we are slowing our efforts in bringing together the research community dealing with andrological issues, much ...
Cryopreservation of Human Pluripotent Stem Cells: Are We Going in the Right Direction?
The first derivation of human embryonic stem cells (hESCs) (Thomson et al., 1998) and the more recently development of human induced pluripotent stem cells (iPSCs) (Park et al., 2008; Takahashi et al., 2007; Takahashi & ...
SLAM Family Receptors and Autoimmunity
The immune system is responsible for the defense against a wide array of pathogens but without responding to each individual’s (self) antigens. Autoimmune diseases are characterized by a loss of tolerance to self antigens ...
Preserved VPS13A distribution and expression in Huntington’s disease: Divergent mechanisms of action for similar movement disorders?
VPS13A disease and Huntington’s disease (HD) are two basal ganglia disorders that may be difficult to distinguish clinically because they have similar symptoms, neuropathological features, and cellular dysfunctions with ...
RTP801 interacts with the tRNA ligase complex and dysregulates its RNA ligase activity in Alzheimer's disease
RTP801/REDD1 is a stress-responsive protein overexpressed in neurodegenerative diseases such as Alzheimer’s disease (AD) that contributes to cognitive deficits and neuroinflammation. Here, we found that RTP801 interacts ...
Effects of dietary cis/trans unsaturated and saturated fatty acids on the glucose metabolites and enzymes of rats.
The aim of the present study was to examine whether the level of dietary cis fatty acid (cFA), or the isomers (trans or cis) and/or the saturation of the fatty acids at high dietary fat levels altered the intracellular ...
Andronet News. Spring/Summar 2025
We are more than halfway through the grant period and in the follow-up of this year’s biggest ANDRONET activity, the European Testis Workshop (ETW). This biennial event gathering ‘testis enthusiasts’ took place in ...
Reciprocal Negative Cross-Talk between Liver X Receptors (LXRs) and STAT1: Effects on IFN-gamma-Induced Inflammatory Responses and LXR-Dependent Gene Expression
Liver X receptors (LXRs) exert key functions in lipid homeostasis and in control of inflammation. In this study we have explored the impact of LXR activation on the macrophage response to the endogenous inflammatory cytokine ...
Cell Differentiation Molecules (HCDM) organization. CD Molecules Nomenclature 2025: Antibody Validation and Expression Profiling of Immune System G Protein-Coupled Receptors.
Monoclonal antibodies (mAbs) targeting cell-surface molecules are pivotal in biomedical research, diagnostic applications, and biotechnology. Over the past four decades, the CD nomenclature system, established by the Human ...
Andronet News. Spring 2024
It is my pleasure to announce a change in the Science Communication Coordination Committee. Ewa Rajpert-De Meyts and Sandra Laurentino swapped their positions, so now Sandra is the Coordinator. Sandra has proven a very ...
Andronet. Winter 2023/2024
After a nice Holiday Season at the end of 2023, we are now looking forward to new activities in the spring. Note that ANDRONET will support several short-term scientific visits for collaborating researchers or clinical ...
A multi-site study on sex differences in cortical thickness in non-demented Parkinson’s disease
Clinical, cognitive, and atrophy characteristics depending on sex have been previously reported in Parkinson’s disease (PD). However, though sex differences in cortical gray matter measures in early drugnaïvepatientshave ...
Andronet News. Autumn 2022
It is a pleasure to inform you that the balance of our Action is very positive at the end of the first grant period and the start of the second one. We have experienced a substantial growth and currently have 216 members ...
A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity
Here we report the characterization of 17T2, a SARS-CoV-2 pan-neutralizing human monoclonal antibody isolated from a COVID-19 convalescent individual infected during the first pandemic wave. 17T2 is a class 1 VH1-58/κ3-20 ...
Follow-Up After Myocardial Infarction to Explore the Stability of Arrhythmogenic Substrate: The Footprint Study.
Objectives This study aimed to characterize the long-term scar remodeling process after an acute myocardial infarction (AMI) and the underlying scar-related arrhythmogenic substrate using serial late gadolinium enhancement ...
Andronet News. Summar 2022
This tool is meant as one of the several ways of communication and will secure that updates or important information drop directly into your mailbox. The frequency and content of the newsletters will be evolving in ...
A high-throughput screening identifies microRNA inhibitors that influence neuronal maintenance and/or response to oxidative stress
Small non-coding RNAs (sncRNAs), including microRNAs (miRNAs) are important post-transcriptional gene expression regulators relevant in physiological and pathological processes. Here, we combined a high-throughput functional ...
