Recent submissions

Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours

de Miguel Luken, Maria; de velasco, Guillermo; Martín Liberal, Juan Jesús; Oberoi, Arjun; MELERO BERMEJO, IGNACIO; GARRALDA, Elena; Joerger, Markus; Hernando-Calvo, Alberto (Publication date: 2025-03-05)

Anti-PD-1 resistance; Solid tumours

Triple Combination of MEK, BET, and CDK Inhibitors Significantly Reduces Human Malignant Peripheral Nerve Sheath Tumors in Mouse Models

zhang, xiaohu; Diazgranados Daza, Adriana Paola; Ortega Bertran, Sara; FERNÁNDEZ RODRÍGUEZ, JUANA; Magallon-Lorenz, Miriam; Creus, Edgar; Valverde, Claudia María; Romagosa, Cleofé (Publication date: 2025-03-04)

Combination of inhibitors; Peripheral nerve sheath; Mouse models

Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial

Harbeck, Nadia; Jerusalem, Guy; Müller, Volkmar; Niikura, Naoki; Viale, Giuseppe; Ciruelos, Eva; Escriva de Romani, Santiago (Publication date: 2024-12-30)

Breast cancer; HER2-positive; Brain metastases

Population-based germline breast cancer gene association studies and meta-analysis to inform wider mainstream testing

Rowlands, Charlie; Allen, Sophie; Domchek, Susan; Evans, Gareth; Hanson, Helen L.; Balmaña, Judith (Publication date: 2024-09-25)

Breast cancer; Mainstream genetic testing; Multigene panel testing

Durable Responses With Mosunetuzumab in Relapsed/Refractory Indolent and Aggressive B-Cell Non-Hodgkin Lymphomas: Extended Follow-Up of a Phase I/II Study

Budde, Lihua; Assouline, Sarit; Sehn, Laurie; Schuster, Stephen; Yoon, Sung-Soo; Yoon, Dok Hyun; Bosch, Francesc (Publication date: 2024-07-01)

Mosunetuzumab; B-cell non-Hodgkin lymphomas; Relapsed

Optimising inter-patient image registration for image-based data mining in breast radiotherapy

Wilson, Fiona; Seoane Ramallo, Alejandro; Jaikuna, Tanwiwat; Azria, David; Chang-Claude, Jenny; De Santis, Maria Carmen; Gutiérrez-Enríquez, Sara; Reyes López, Victoria (Publication date: 2024-10-30)

Breast radiotherapy; Image-based data mining; Spatial normalisation

Treatment of advanced BP-NETS with lanreotide autogel/depot vs placebo: the phase III SPINET study

BAUDIN, Eric; Hörsch, Dieter; Singh, Simron; CAPLIN, MARTYN; Wolin, Edward; Capdevila Castillon, Jaume (Publication date: 2024-09-16)

Atypical carcinoid; Bronchopulmonary neuroendocrine tumors; Typical carcinoid

Impact of SARS-CoV-2 vaccines and recent chemotherapy on COVID-19 morbidity and mortality in patients with soft tissue sarcoma: an analysis from the OnCovid registry

Cortellini, Alessio; Mazzocca, Alessandro; Orlando, Sarah; Romandini, Davide; Valverde Morales, Claudia Maria; Eremiev, Simeón; Vincenzi, Bruno; Aguilar-Company, Juan; Ruiz- Camps, Isabel (Publication date: 2024-06-18)

COVID-19; Soft tissue sarcoma; Vaccines

Changes In Serum CXCL13 Levels Are Associated With Outcomes of Colorectal Cancer Patients Undergoing First-Line Oxaliplatin-Based Treatment

Cabrero de las Heras, sara; Hernández-Yagüe, Xavier; González Valencia, Andrea; Losa, Fernando; Soler Gonzalez, Gemma; Bugès Sanchez, Cristina; Baraibar, Iosune (Publication date: 2024-06-14)

Colorectal cancer; Tertiary lymphoid structures; Predictive biomarkers

Long-term follow-up of efficacy and safety of selinexor maintenance treatment in patients with TP53wt advanced or recurrent endometrial cancer: A subgroup analysis of the ENGOT-EN5/GOG-3055/SIENDO study

VALABREGA, Giorgio; Hamilton, Erika; Sehouli, Jalid; Fariñas-Madrid, Lorena; Makker, Vicky; Pérez-Fidalgo, J. Alejandro; Van Gorp, Toon (Publication date: 2024-06-14)

Cancer biomarker; Endometrial neoplasm; P53 tumor-suppressor protein

Complete response of metastatic cutaneous squamous cell carcinoma and multiple locally advanced basal cell carcinomas with concomitant pembrolizumab and sonidegib therapy

Ferrer Fábrega, Berta; González-Cruz, Carlos; MUÑOZ COUSELO, EVA; Ortiz Velez, Carolina; Garcia-Patos Briones, Vicente; Ferrandiz-Pulido, Carla (Publication date: 2024-04-11)

Basal cell carcinoma; Immunomodulatory therapy; Squamous cell carcinoma

Tumor analysis of MMR genes in Lynch-like syndrome: Challenges associated with results interpretation

Rofes, Paula; Duenas Cid, Nuria; del Valle, Jesús; Navarro, Matilde; Balmaña, Judith; Ramon y Cajal, Teresa (Publication date: 2024-04-09)

Lynch syndrome; Mismatch repair genes; Tumor testing

Final Results From the Randomized Phase III ASCENT Clinical Trial in Metastatic Triple-Negative Breast Cancer and Association of Outcomes by Human Epidermal Growth Factor Receptor 2 and Trophoblast Cell Surface Antigen 2 Expression

Tolaney, Sara; Loirat, Delphine; Punie, Kevin; Bardia, Aditya; Rugo, Hope; Oliveira, Mafalda (Publication date: 2024-05-21)

Metastatic triple-negative breast cancer; Human epidermal growth factor receptor; Trophoblast cell surface

A Validated Highly Sensitive Microsatellite Instability Assay Accurately Identifies Individuals Harboring Biallelic Germline PMS2 Pathogenic Variants in Constitutional Mismatch Repair Deficiency

Marín Nieto, Fátima; Canet-Hermida, Júlia; Bianchi, Vanessa; Chung, Jiil; Wimmer, Katharina; Foulkes, William; Sabado, Constantino; Carrasco Lopez, Estela (Publication date: 2024-05-21)

Inestabilitat de microsatèl·lits; Variants patògenes

SEAMARK: phase II study of first-line encorafenib and cetuximab plus pembrolizumab for MSI-H/dMMR BRAFV600E-mutant mCRC

Kopetz, Scott; Bekaii-Saab, Tanios; Elez, Elena; Tabernero, Josep; taieb, julien; Yoshino, Takayuki (Publication date: 2024-04-09)

Immunotherapy; Metastatic colorectal cancer; Targeted therapy

Delphi consensus for the third-line treatment of metastatic colorectal cancer

Vera, Ruth; Rivera, Fernando; García-Alfonso, Pilar; Aranda Aguilar, Enrique; Elez, Elena (Publication date: 2024-05-31)

Delphi; Quality of life; Regorafenib

Predictability of B cell clonal persistence and immunosurveillance in breast cancer

Sammut, Stephen John; Galson, Jacob; Minter, Ralph; Sun, Bo; chin, suet-feung; De Mattos-Arruda, Leticia; Seoane, Joan (Publication date: 2024-05-08)

B cell; Immunosurveillance; Breast cancer

Prevalence of Homologous Recombination Deficiency Among Patients With Germline RAD51C/D Breast or Ovarian Cancer

Romey, Marcel; Llort, Gemma; Torres-Esquius, Sara; Llop-Guevara, Alba; Gutiérrez-Enríquez, Sara; Teule, Alex; Serra, Violeta; Balmaña, Judith (Publication date: 2024-04-29)

Prevalence; Homologous recombination deficiency; Breast cancer

Early-Stage Breast Cancer Detection in Breast Milk

Ortiz Velez, Carolina; Martin Casado, Agatha; Martínez-Sabadell, Alex; Garcia-Ruiz, Itziar; Miranda, Ignacio; Morales Comas, Clara; Viaplana, Cristina; Bayó Puxan, Neus; Miquel Aymar, Josep Maria; Gómez-Rey, Marina; Dienstmann, Rodrigo; Sanso, Miriam; Saura Manich, Cristina; Matito, Judit; ARENAS LAHUERTA, ENRIQUE JAVIER; Suñol-Camas, Anna; Carrasco Lopez, Estela; Peg, Vicente; Nuciforo, Paolo; Gonzalez Medina, Alberto; Villacampa Javierre, Guillermo; Arévalo Martínez, Silvia; Espinosa-Bravo, Martin; Balmaña, Judith; Arribas, Joaquin; Tabernero, Josep; Vivancos, Ana (Publication date: 2023-10-11)

Breast cancer; Breast milk

2023 GEIS Guidelines for gastrointestinal stromal tumors

Asencio, Jose Manuel; López-Guerrero, José Antonio; Rubió-Casadevall, Jordi; BAGUE, SILVIA; Serrano, Cesar; Martin-Broto, Javier (Publication date: 2023-09-19)

Avapritinib; Gastrointestinal stromal tumor; Surgery

Articles científics - VHIO: Recent submissions

Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours ﻿

Triple Combination of MEK, BET, and CDK Inhibitors Significantly Reduces Human Malignant Peripheral Nerve Sheath Tumors in Mouse Models ﻿

Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial ﻿

Population-based germline breast cancer gene association studies and meta-analysis to inform wider mainstream testing ﻿

Durable Responses With Mosunetuzumab in Relapsed/Refractory Indolent and Aggressive B-Cell Non-Hodgkin Lymphomas: Extended Follow-Up of a Phase I/II Study ﻿

Optimising inter-patient image registration for image-based data mining in breast radiotherapy ﻿

Treatment of advanced BP-NETS with lanreotide autogel/depot vs placebo: the phase III SPINET study ﻿

Impact of SARS-CoV-2 vaccines and recent chemotherapy on COVID-19 morbidity and mortality in patients with soft tissue sarcoma: an analysis from the OnCovid registry ﻿

Changes In Serum CXCL13 Levels Are Associated With Outcomes of Colorectal Cancer Patients Undergoing First-Line Oxaliplatin-Based Treatment ﻿

Long-term follow-up of efficacy and safety of selinexor maintenance treatment in patients with TP53wt advanced or recurrent endometrial cancer: A subgroup analysis of the ENGOT-EN5/GOG-3055/SIENDO study ﻿

Complete response of metastatic cutaneous squamous cell carcinoma and multiple locally advanced basal cell carcinomas with concomitant pembrolizumab and sonidegib therapy ﻿

Tumor analysis of MMR genes in Lynch-like syndrome: Challenges associated with results interpretation ﻿

Final Results From the Randomized Phase III ASCENT Clinical Trial in Metastatic Triple-Negative Breast Cancer and Association of Outcomes by Human Epidermal Growth Factor Receptor 2 and Trophoblast Cell Surface Antigen 2 Expression ﻿

A Validated Highly Sensitive Microsatellite Instability Assay Accurately Identifies Individuals Harboring Biallelic Germline PMS2 Pathogenic Variants in Constitutional Mismatch Repair Deficiency ﻿

SEAMARK: phase II study of first-line encorafenib and cetuximab plus pembrolizumab for MSI-H/dMMR BRAFV600E-mutant mCRC ﻿

Delphi consensus for the third-line treatment of metastatic colorectal cancer ﻿

Predictability of B cell clonal persistence and immunosurveillance in breast cancer ﻿

Prevalence of Homologous Recombination Deficiency Among Patients With Germline RAD51C/D Breast or Ovarian Cancer ﻿

Early-Stage Breast Cancer Detection in Breast Milk ﻿

2023 GEIS Guidelines for gastrointestinal stromal tumors ﻿