Currently, poverty and inequality are crucial social issues around the world. They demand objective evaluations with the purpose of defining policies and prioritizing actions. Most of the times the most important problem lies on the fact that individuals under poverty circumstances or belonging to vulnerable collectives cannot escape these conditions by themselves and need external assistance or interventions. Another added difficulty is that both poverty and inequality can be studied from different angles and require a multidimensional approach whose definition is not straightforward. There exists a vicious cycle defined by a collection of determinants or events that lead to a phenomenon in which various disadvantages work circularly so that it is impossible for individuals or households to break the cycle. In this context, setting the background in which these vicious cycles arise can be helpful in order to conduct in-depth studies as a first step to establishing possible solutions. Even though many researchers have proposed alternative schemes for the poverty’s vicious circle, none has been introduced for inequality. In this contribution, a meaningful and integrated cycle is defined for inequality at two different levels: first of all, at an individual level; secondly, at a collective level in which a certain group is made vulnerable. This cycle includes similar parameter as those comprised in the poverty cycle such as income, access to education and access to healthcare. However, it additionally places emphasis on other aspects such as participation in politics and access to leadership positions. Besides, a conceptual and analytical framework is built, whose objective is to describe ways in which infrastructure, innovation and industry can help interrupt the continuation of the cycle. This model integrates a collection of different measures that is to be potentially helpful for policy makers. Additionally, the frame accounts for not only the fight of current existing cycles, but also of future generations ones, hence considering sustainability dimensions.