Removal of the chiral inductor from phenylglycinol-derived tricyclic lactams. Unexpected generation of chiral trans-hydrochromene lactones

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RECERCAT Home > Universitat de Barcelona > Farmacologia, Toxicologia i Química Terapèutica > Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) > View document

To access the full text documents, please follow this link: http://hdl.handle.net/2445/127602

dc.contributor	Universitat de Barcelona
dc.contributor.author	Griera Farres, Rosa
dc.contributor.author	Pinto, Alexandre
dc.contributor.author	Fabregat, Robert
dc.contributor.author	Cots, Èric
dc.contributor.author	Bosch Cartes, Joan
dc.contributor.author	Amat Tusón, Mercedes
dc.date	2019-01-25T10:06:09Z
dc.date	2019-12-31T06:10:14Z
dc.date	2018
dc.date	2019-01-25T10:06:09Z
dc.identifier.citation	1570-1786
dc.identifier.citation	679217
dc.identifier.uri	http://hdl.handle.net/2445/127602
dc.format	5 p.
dc.format	application/pdf
dc.language.iso	eng
dc.publisher	Bentham Science Publishers
dc.relation	Versió postprint del document publicat a: https://doi.org/10.2174/1570178615666171213143657
dc.relation	Letters In Organic Chemistry, 2018, vol. 15, num. 5, p. 335-339
dc.relation	https://doi.org/10.2174/1570178615666171213143657
dc.rights	(c) Bentham Science Publishers, 2018
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	Alcaloides
dc.subject	Lactames
dc.subject	Síntesi asimètrica
dc.subject	Alkaloids
dc.subject	Lactams
dc.subject	Asymmetric synthesis
dc.title	Removal of the chiral inductor from phenylglycinol-derived tricyclic lactams. Unexpected generation of chiral trans-hydrochromene lactones
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/acceptedVersion
dc.description.abstract	In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones, a procedure for the generation of enantiopure trans-hydrochromene lactones, by treatment of (R)- phenylglycinol-derived oxazoloquinolone lactams with Na/liq. NH3 followed by acidification, has been developed.

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