Removal of the chiral inductor from phenylglycinol-derived tricyclic lactams. Unexpected generation of chiral trans-hydrochromene lactones

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Title:	Removal of the chiral inductor from phenylglycinol-derived tricyclic lactams. Unexpected generation of chiral trans-hydrochromene lactones
Author:	Griera Farres, Rosa; Pinto, Alexandre; Fabregat, Robert; Cots, Èric; Bosch Cartes, Joan; Amat Tusón, Mercedes
Other authors:	Universitat de Barcelona
Abstract:	In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones, a procedure for the generation of enantiopure trans-hydrochromene lactones, by treatment of (R)- phenylglycinol-derived oxazoloquinolone lactams with Na/liq. NH3 followed by acidification, has been developed.
Subject(s):	-Alcaloides -Lactames -Síntesi asimètrica -Alkaloids -Lactams -Asymmetric synthesis
Rights:	(c) Bentham Science Publishers, 2018
Document type:	Article Article - Accepted version
Published by:	Bentham Science Publishers
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