Sistema de Salut de Catalunya
[Roerink AMC, Nelissen RGHH] Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands. [Holder C] South Australian Health and Medical Research Institute (SAHMRI), Adelaide, Australia. [Graves SE] Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR), Adelaide, Australia. Clinical and Health Sciences, University of South Australia, Adelaide, Australia. [Dunbar M] Division of Orthopaedics, Dalhousie University, Halifax, Nova Scotia, Canada. Canadian Joint Replacement Registry, Canada. [Bohm E] Canadian Joint Replacement Registry, Canada. Concordia Joint Replacement Group, University of Manitoba, Winnipeg, Canada. [Espallargues M] Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS), Barcelona, Spain. [Arias-de la Torre J] Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS), Barcelona, Spain. Care in Long Term Conditions Research Division, King's College London, London, UK. CIBER Epidemiology and Public Health (CIBERESP), Madrid. Institute of Biomedicine (IBIOMED), Universidad de León, León, Spain
Departament de Salut
2025-03-12T12:53:26Z
2025-03-12T12:53:26Z
2024-12-10
Arthroplasty; Foot and ankle; Hip; Infection
Artroplastia; Pie y tobillo; Cadera; Infección
Artroplàstia; Peu i turmell; Maluc; Infecció
We aimed to determine sex differences for periprosthetic joint infections after primary arthroplasty of the hip, knee, ankle, and shoulder in osteoarthritis patients in an international perspective. This is a multinational combined arthroplasty registry study. Each arthroplasty registry performed Cox-regression analysis of their data and reported the crude and adjusted hazard ratios (HR) with an a priori designed data form. A random-effects model was used to pool these HRs to estimate an overall HR with 95% confidence interval (CI). Adjustment was undertaken for patient age, BMI, ASA grade, type of fixation, and type of implant. 9 arthroplasty registries participated. Patients who received primary total joint arthroplasty for primary osteoarthritis were considered: 2,134,313 hip arthroplasties, 2,658,237 knee arthroplasties, 57,889 shoulder arthroplasties, and 8,445 ankle arthroplasties. We calculated hazard ratios (HR) for the overall risk of complete revision due to infection for each implant type and follow-up. The pooled HR for revision due to infection for men compared with women at 1-year follow-up was 1.60 (95% confidence interval [CI] 1.42-1.80) for hip arthroplasties; 2.06 (CI 1.90-2.46) for knee arthroplasties; 4.51 (CI 2.99-6.80) for shoulder arthroplasties; and 0.87 (CI 0.46-1.62) for ankle arthroplasties. These results remained consistent over time and were identified in both unadjusted and adjusted models. Men have a higher risk of revision due to infection than women after primary hip, knee, and shoulder arthroplasty. No evidence of difference was found for ankle arthroplasty. These elevated relative risks persist in the fully adjusted investigations and over the 10-year postoperative period studied.
Article
Published version
English
Artroplàstia - Avaluació; Artroplàstia - Registres - Catalunya; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Orthopedic Procedures::Arthroplasty::Arthroplasty, Replacement; Other subheadings::Other subheadings::Other subheadings::/adverse effects; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Orthopedic Procedures::Arthroplasty::Arthroplasty, Replacement::Arthroplasty, Replacement, Hip; Other subheadings::Other subheadings::Other subheadings::/adverse effects; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Orthopedic Procedures::Arthroplasty::Arthroplasty, Replacement::Arthroplasty, Replacement, Knee; Other subheadings::Other subheadings::Other subheadings::/adverse effects; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Orthopedic Procedures::Arthroplasty::Arthroplasty, Replacement::Arthroplasty, Replacement, Ankle; Other subheadings::Other subheadings::Other subheadings::/adverse effects; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Surgical Procedures, Operative::Prosthesis Implantation::Arthroplasty, Replacement::Surgical Procedures, Operative::Arthroplasty, Replacement, Shoulder; Other subheadings::Other subheadings::Other subheadings::/adverse effects; DISEASES::Musculoskeletal Diseases::Joint Diseases::Arthritis::Osteoarthritis; Other subheadings::Other subheadings::Other subheadings::/surgery; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors; HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Sex Factors; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución; Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución::artroplastia de sustitución de cadera; Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución::artroplastia de sustitución de rodilla; Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución::artroplastia de sustitución del tobillo; Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución::artroplastia del hombro con sustitución protésica; Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos; ENFERMEDADES::enfermedades musculoesqueléticas::artropatías::artritis::osteoartritis; Otros calificadores::Otros calificadores::Otros calificadores::/cirugía; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo; ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::factores epidemiológicos::factores sexuales
Medical Journals Sweden
Acta Orthopaedica;95
https://www.doi.org/10.2340/17453674.2024.42183
Attribution-NonCommercial 4.0 International
https://creativecommons.org/licenses/by/4.0/
