dc.contributor
[Roerink AMC, Nelissen RGHH] Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands. [Holder C] South Australian Health and Medical Research Institute (SAHMRI), Adelaide, Australia. [Graves SE] Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR), Adelaide, Australia. Clinical and Health Sciences, University of South Australia, Adelaide, Australia. [Dunbar M] Division of Orthopaedics, Dalhousie University, Halifax, Nova Scotia, Canada. Canadian Joint Replacement Registry, Canada. [Bohm E] Canadian Joint Replacement Registry, Canada. Concordia Joint Replacement Group, University of Manitoba, Winnipeg, Canada. [Espallargues M] Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS), Barcelona, Spain. [Arias-de la Torre J] Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS), Barcelona, Spain. Care in Long Term Conditions Research Division, King's College London, London, UK. CIBER Epidemiology and Public Health (CIBERESP), Madrid. Institute of Biomedicine (IBIOMED), Universidad de León, León, Spain
dc.contributor
Departament de Salut
dc.contributor.author
Roerink, Anne
dc.contributor.author
Nelissen, Rob
dc.contributor.author
Holder, Carl
dc.contributor.author
Graves, Stephen
dc.contributor.author
Dunbar, MD FRCSC PhD FCAHS, Michael
dc.contributor.author
Bohm, Eric
dc.contributor.author
Espallargues-Carreras, Mireia
dc.contributor.author
Arias-de la Torre, Jorge
dc.date.accessioned
2025-10-27T09:41:28Z
dc.date.available
2025-10-27T09:41:28Z
dc.date.issued
2025-03-12T12:53:26Z
dc.date.issued
2025-03-12T12:53:26Z
dc.date.issued
2024-12-10
dc.identifier
Roerink AMC, Nelissen RGHH, Holder C, Graves SE, Dunbar M, Bohm E, et al. Sex-based differences in risk of revision for infection after hip, knee, shoulder, and ankle arthroplasty in osteoarthritis patients: a multinational registry study of 4,800,000 implants. Acta Orthop. 2024 Dec 10;95:730-736.
dc.identifier
http://hdl.handle.net/11351/12753
dc.identifier
10.2340/17453674.2024.42183
dc.identifier.uri
http://hdl.handle.net/11351/12753
dc.description.abstract
Arthroplasty; Foot and ankle; Hip; Infection
dc.description.abstract
Artroplastia; Pie y tobillo; Cadera; Infección
dc.description.abstract
Artroplàstia; Peu i turmell; Maluc; Infecció
dc.description.abstract
We aimed to determine sex differences for periprosthetic joint infections after primary arthroplasty of the hip, knee, ankle, and shoulder in osteoarthritis patients in an international perspective.
This is a multinational combined arthroplasty registry study. Each arthroplasty registry performed Cox-regression analysis of their data and reported the crude and adjusted hazard ratios (HR) with an a priori designed data form. A random-effects model was used to pool these HRs to estimate an overall HR with 95% confidence interval (CI). Adjustment was undertaken for patient age, BMI, ASA grade, type of fixation, and type of implant. 9 arthroplasty registries participated. Patients who received primary total joint arthroplasty for primary osteoarthritis were considered: 2,134,313 hip arthroplasties, 2,658,237 knee arthroplasties, 57,889 shoulder arthroplasties, and 8,445 ankle arthroplasties. We calculated hazard ratios (HR) for the overall risk of complete revision due to infection for each implant type and follow-up.
The pooled HR for revision due to infection for men compared with women at 1-year follow-up was 1.60 (95% confidence interval [CI] 1.42-1.80) for hip arthroplasties; 2.06 (CI 1.90-2.46) for knee arthroplasties; 4.51 (CI 2.99-6.80) for shoulder arthroplasties; and 0.87 (CI 0.46-1.62) for ankle arthroplasties. These results remained consistent over time and were identified in both unadjusted and adjusted models.
Men have a higher risk of revision due to infection than women after primary hip, knee, and shoulder arthroplasty. No evidence of difference was found for ankle arthroplasty. These elevated relative risks persist in the fully adjusted investigations and over the 10-year postoperative period studied.
dc.format
application/pdf
dc.format
application/pdf
dc.format
application/pdf
dc.publisher
Medical Journals Sweden
dc.relation
Acta Orthopaedica;95
dc.relation
https://www.doi.org/10.2340/17453674.2024.42183
dc.rights
Attribution-NonCommercial 4.0 International
dc.rights
https://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Artroplàstia - Avaluació
dc.subject
Artroplàstia - Registres - Catalunya
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Orthopedic Procedures::Arthroplasty::Arthroplasty, Replacement
dc.subject
Other subheadings::Other subheadings::Other subheadings::/adverse effects
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Orthopedic Procedures::Arthroplasty::Arthroplasty, Replacement::Arthroplasty, Replacement, Hip
dc.subject
Other subheadings::Other subheadings::Other subheadings::/adverse effects
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Orthopedic Procedures::Arthroplasty::Arthroplasty, Replacement::Arthroplasty, Replacement, Knee
dc.subject
Other subheadings::Other subheadings::Other subheadings::/adverse effects
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Orthopedic Procedures::Arthroplasty::Arthroplasty, Replacement::Arthroplasty, Replacement, Ankle
dc.subject
Other subheadings::Other subheadings::Other subheadings::/adverse effects
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Surgical Procedures, Operative::Prosthesis Implantation::Arthroplasty, Replacement::Surgical Procedures, Operative::Arthroplasty, Replacement, Shoulder
dc.subject
Other subheadings::Other subheadings::Other subheadings::/adverse effects
dc.subject
DISEASES::Musculoskeletal Diseases::Joint Diseases::Arthritis::Osteoarthritis
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Other subheadings::Other subheadings::Other subheadings::/surgery
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors
dc.subject
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Sex Factors
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución::artroplastia de sustitución de cadera
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución::artroplastia de sustitución de rodilla
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución::artroplastia de sustitución del tobillo
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución::artroplastia del hombro con sustitución protésica
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos
dc.subject
ENFERMEDADES::enfermedades musculoesqueléticas::artropatías::artritis::osteoartritis
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/cirugía
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo
dc.subject
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::factores epidemiológicos::factores sexuales
dc.title
Sex-based differences in risk of revision for infection after hip, knee, shoulder, and ankle arthroplasty in osteoarthritis patients: a multinational registry study of 4,800,000 implants
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
