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dc.contributor.author | Montull, Beatriz |
---|---|
dc.contributor.author | Menéndez, Rosario |
dc.contributor.author | Torres Martí, Antoni |
dc.contributor.author | Reyes, Soledad |
dc.contributor.author | Méndez, Raúl |
dc.contributor.author | Zalacaín, Rafael |
dc.contributor.author | Capelastegui, Alberto |
dc.contributor.author | Rajas, Olga |
dc.contributor.author | Borderías, Luis |
dc.contributor.author | Martín Villasclaras, Juan |
dc.contributor.author | Bello, Salvador |
dc.contributor.author | Alfageme, Inmaculada |
dc.contributor.author | Rodríguez de Castro, Felipe |
dc.contributor.author | Rello Condomines, Jordi |
dc.contributor.author | Molinos, Luis |
dc.contributor.author | Ruiz Manzano, Juan |
dc.date | 2017-01-02T14:43:31Z |
dc.date | 2017-01-02T14:43:31Z |
dc.date | 2016-01-04 |
dc.date | 2017-01-02T14:43:37Z |
dc.identifier | 1932-6203 |
dc.identifier | 659742 |
dc.identifier | 26727202 |
dc.identifier.uri | http://hdl.handle.net/2445/105203 |
dc.description | Background Severe sepsis, may be present on hospital arrival in approximately one-third of patients with community-acquired pneumonia (CAP). Objective To determine the host characteristics and micro-organisms associated with severe sepsis in patients hospitalized with CAP. Results We performed a prospective multicenter cohort study in 13 Spanish hospital, on 4070 hospi- talized CAP patients, 1529 of whom (37.6%) presented with severe sepsis. Severe sepsis CAP was independently associated with older age ( > 65 years), alcohol abuse (OR, 1.31; 95% CI, 1.07 - 1.61), chronic obstructive pulmonary disease (COPD) (OR, 1.75; 95% CI, 1.50 - 2.04) and renal disease (OR, 1.57; 95% CI, 1.21 - 2.03), whereas prior antibiotic treat- ment was a protective factor (OR, 0.62; 95% CI, 0.52 - 0.73). Bacteremia (OR, 1.37; 95% CI, 1.05 - 1.79), S pneumoniae (OR, 1.59; 95% CI, 1.31 - 1.95) and mixed microbial etiology (OR, 1.65; 95% CI, 1.10 - 2.49) were associated with severe sepsis CAP. Conclusions CAP patients with COPD, renal disease and alcohol abuse, as well as those with CAP due to S pneumonia or mixed micro-organisms are more likely to present to the hospital with severe sepsis. |
dc.format | 9 p. |
dc.format | application/pdf |
dc.language | eng |
dc.publisher | Public Library of Science (PLoS) |
dc.relation | Reproducció del document publicat a: https://doi.org/10.1371/journal.pone.0145929 |
dc.relation | PLoS One, 2016, vol. 11, num. 1, p. e0145929 |
dc.relation | https://doi.org/10.1371/journal.pone.0145929 |
dc.rights | cc-by (c) Montull, Beatriz et al., 2016 |
dc.rights | http://creativecommons.org/licenses/by/3.0/es |
dc.rights | info:eu-repo/semantics/openAccess |
dc.subject | Septicèmia |
dc.subject | Malalties pulmonars obstructives cròniques |
dc.subject | Pneumònia |
dc.subject | Antibiòtics |
dc.subject | Septicemia |
dc.subject | Chronic obstructive pulmonary diseases |
dc.subject | Pneumonia |
dc.subject | Antibiotics |
dc.title | Predictors of severe sepsis among patients hospitalized for community-acquired pneumonia |
dc.type | info:eu-repo/semantics/article |
dc.type | info:eu-repo/semantics/publishedVersion |