Título:
|
Abdominal distension after eating lettuce: the role of intestinal gas evaluated in vitro and by abdominal CT imaging
|
Autor/a:
|
Barba, Elisabeth; Sánchez García, Borja; Burri, Emanuel; Accarino Garaventa, Anna María; Monclús Lahoya, Eva; Navazo Álvaro, Isabel; Guarner Aguilar, Francisco; Margolles Barros, Abelardo; Azpiroz Vidaur, Fernando
|
Otros autores:
|
Universitat Politècnica de Catalunya. Departament de Ciències de la Computació; Universitat Politècnica de Catalunya. ViRVIG - Grup de Recerca en Visualització, Realitat Virtual i Interacció Gràfica |
Abstract:
|
Background: Some patients complain that eating lettuce, gives them gas and abdominal distention. Our aim was to determine to what extent the patients' assertion is sustained by evidence.
Methods: An in vitro study measured the amount of gas produced during the process of fermentation by a preparation of human colonic microbiota (n = 3) of predigested lettuce, as compared to beans, a high gas-releasing substrate, to meat, a low gas-releasing substrate, and to a nutrient-free negative control. A clinical study in patients complaining of abdominal distention after eating lettuce (n = 12) measured the amount of intestinal gas and the morphometric configuration of the abdominal cavity in abdominal CT scans during an episode of lettuce-induced distension as compared to basal conditions.
Key Results: Gas production by microbiota fermentation of lettuce in vitro was similar to that of meat (P = .44), lower than that of beans (by 78 ± 15%; P < .001) and higher than with the nutrient-free control (by 25 ± 19%; P = .05). Patients complaining of abdominal distension after eating lettuce exhibited an increase in girth (35 ± 3 mm larger than basal; P < .001) without significant increase in colonic gas content (39 ± 4 mL increase; P = .071); abdominal distension was related to a descent of the diaphragm (by 7 ± 3 mm; P = .027) with redistribution of normal abdominal contents.
Conclusion and Inferences: Lettuce is a low gas-releasing substrate for microbiota fermentation and lettuce-induced abdominal distension is produced by an uncoordinated activity of the abdominal walls. Correction of the somatic response might be more effective than the current dietary restriction strategy. |
Abstract:
|
Peer Reviewed |
Materia(s):
|
-Àrees temàtiques de la UPC::Ciències de la salut::Medicina::Medicina interna -Gastrointestinal gas -Gasos gastrointestinals |
Derechos:
|
Attribution 3.0 Spain
http://creativecommons.org/licenses/by/3.0/es/ |
Tipo de documento:
|
Artículo - Versión publicada Artículo |
Editor:
|
John Wiley and Sons Ltd.
|
Compartir:
|
|