Title:
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Alginate electrodeposition onto three-dimensional porous Co-Ni films as drug delivery platform
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Author:
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García-Torres, José; Gispert, C.; Gómez, Elvira; Vallés Giménez, Elisa
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Other authors:
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Universitat de Barcelona |
Abstract:
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Three-dimensional porous Co-Ni films/alginate hybrid materials have been successfully prepared by electrodeposition to be used as a steerable magnetic device for drug delivery. Firstly, 3D porous Co-Ni films were prepared as substrates for the subsequent electrodeposition of the alginate biopolymer. Cyclic voltammetry, galvanostatic and potentiostatic studies were performed to establish the best conditions to obtain porous Co-Ni films. The electrochemical experiments were carried out in an electrolyte containing the metal salts and ammonium chloride at low pHs. In a second stage, the electrochemical deposition of alginate as a biocompatible polymer drug delivery carrier was performed. The characteristics of the alginate matrix were investigated in terms of electrochemical properties, morphology and drug release. The hybrid material obtained showed soft-magnetic behavior and drug release indicating its suitability to be used as a steerable magnetic drug delivery device. |
Subject(s):
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-Deposició (Metal·lúrgia) -Electroquímica -Hemoglobina -Plating -Electrochemistry -Hemoglobin |
Rights:
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(c) García-Torres, José et al., 2015
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Document type:
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Article Article - Accepted version |
Published by:
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Royal Society of Chemistry
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