Title:
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Full-term pregnancy in breast cancer survivor with fertility preservation: A case report and review of literature
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Author:
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Garrido-Marín, Marta; Argacha, Pedro Maria; Fernández, Luís; Molfino, Florencia; Martínez Soler, Fina; Tortosa i Moreno, Avelina; Giménez Bonafé, Pepita
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Other authors:
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Universitat de Barcelona |
Abstract:
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A 43-year-old woman with an associated history of gynecological pathology and breast cancer with only one cryopreserved embryo wished to be a mother. Several factors that influenced the success of the pregnancy in this case were analyzed. Favorable factors included: triple positive breast cancer [positive hormone receptors and positive human epidermal growth factor receptor 2], which is more hormosensitive and chemosensitive; absence of metastasis; correct endometrium preparation; and the patient's optimistic attitude and strict health habits. In contrast, the factors against success were: breast cancer; adjuvant breast cancer therapy gonadotoxicity; the age of the patient (> 40-year-old); endometriosis; ovarian cyst; hydrosalpinx; submucosal fibroids and the respective associated surgery done for the above-mentioned pathology (all resolved prior to the embryo transfer); and a low quantity of ovules (low ovarian reserve) after ovarian stimulation. This is a very special clinical case of a patient with theoretically low pregnancy success probability due to the consecutive accumulation of gynecological and oncological pathologies, who nonetheless became pregnant and delivered a full-term infant and was able to provide adequate breastfeeding. |
Subject(s):
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-Càncer de mama -Fecunditat -Embaràs -Fecundació in vitro humana -Endometriosi -Ressenyes sistemàtiques (Investigació mèdica) -Breast cancer -Fertility -Pregnancy -Human in vitro fertilization -Endometriosis -Systematic reviews (Medical research) |
Rights:
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cc-by-nc (c) Garrido-Marín, Marta et al., 2019
http://creativecommons.org/licenses/by-nc/3.0/es |
Document type:
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Article Article - Published version |
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