Title:
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Stereoselective oxidation of titanium(IV) enolates with oxygen
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Author:
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Gómez Palomino, Alejandro; Romea, Pedro; Urpí Tubella, Fèlix
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Other authors:
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Universitat de Barcelona |
Abstract:
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A novel approach to synthesize enantiomerically pure α-hydroxy carboxylic derivatives is reported. A highly stereoselective oxidation of titanium(IV) enolates from chiral N-acyloxazolidinones is performed with oxygen under simple experimental conditions that do not require any reducing steps. The success of this approach depends on the biradical character of titanium(IV) enolates. |
Subject(s):
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-Titani -Estereoquímica -Quiralitat -Titanium -Stereochemistry -Chirality |
Rights:
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(c) Georg Thieme Verlag, 2018
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Document type:
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Article Article - Accepted version |
Published by:
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Georg Thieme Verlag
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