dc.contributor.author |
Formiga Pérez, Francesc |
dc.contributor.author |
Ferrer, Assumpta |
dc.contributor.author |
Padros, Gloria |
dc.contributor.author |
Montero Saez, Abelardo |
dc.contributor.author |
Giménez Argente, Carme |
dc.contributor.author |
Corbella, Xavier |
dc.date |
2018-12-19T12:30:48Z |
dc.date |
2018-12-19T12:30:48Z |
dc.date |
2016-04-18 |
dc.date |
2018-12-19T12:30:48Z |
dc.identifier.citation |
1176-9092 |
dc.identifier.citation |
676191 |
dc.identifier.uri |
http://hdl.handle.net/2445/127057 |
dc.format |
8 p. |
dc.format |
application/pdf |
dc.language.iso |
eng |
dc.publisher |
Dove Medical Press |
dc.relation |
Reproducció del document publicat a: https://doi.org/10.2147/CIA.S101447 |
dc.relation |
Clinical Interventions in Aging, 2016, vol. 11, p. 437-444 |
dc.relation |
https://doi.org/10.2147/CIA.S101447 |
dc.rights |
cc-by-nc (c) Formiga Pérez, Francesc et al., 2016 |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.rights |
http://creativecommons.org/licenses/by-nc/3.0/es |
dc.subject |
Mortalitat |
dc.subject |
Geriatria |
dc.subject |
Envelliment |
dc.subject |
Comorbiditat |
dc.subject |
Mortality |
dc.subject |
Geriatrics |
dc.subject |
Aging |
dc.subject |
Comorbidity |
dc.title |
Evidence of functional declining and global comorbidity measured at baseline proved to be the strongest predictors for long-term death in elderly community residents aged 85 years: a 5-year follow-up evaluation, the OCTABAIX study |
dc.type |
info:eu-repo/semantics/article |
dc.type |
info:eu-repo/semantics/publishedVersion |
dc.description.abstract |
Objective: To investigate the predictive value of functional impairment, chronic conditions, and laboratory biomarkers of aging for predicting 5-year mortality in the elderly aged 85 years. Methods: Predictive value for mortality of different geriatric assessments carried out during the OCTABAIX study was evaluated after 5 years of follow-up in 328 subjects aged 85 years. Measurements included assessment of functional status comorbidity, along with laboratory tests on vitamin D, cholesterol, CD4/CD8 ratio, hemoglobin, and serum thyrotropin. Results: Overall, the mortality rate after 5 years of follow-up was 42.07%. Bivariate analysis showed that patients who survived were predominantly female (P=0.02), and they showed a significantly better baseline functional status for both basic (P<0.001) and instrumental (P<0.001) activities of daily living (Barthel and Lawton index), better cognitive performance (Spanish version of the Mini-Mental State Examination) (P<0.001), lower comorbidity conditions (Charlson) (P<0.001), lower nutritional risk (Mini Nutritional Assessment) (P<0.001), lower risk of falls (Tinetti gait scale) (P<0.001), less percentage of heart failure (P=0.03) and chronic obstructive pulmonary disease (P=0.03), and took less chronic prescription drugs (P=0.002) than nonsurvivors. Multivariate Cox regression analysis identified a decreased score in the Lawton index (hazard ratio 0.86, 95% confidence interval: 0.78-0.91) and higher comorbidity conditions (hazard ratio 1.20, 95% confidence interval: 1.08-1.33) as independent predictors of mortality at 5 years in the studied population. Conclusion: The ability to perform instrumental activities of daily living and the global comorbidity assessed at baseline were the predictors of death, identified in our 85-year-old community-dwelling subjects after 5 years of follow-up. |