A genome-wide association study of marginal zone lymphoma shows association to the HLA region

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RECERCAT Home > Universitat de Barcelona > Institut d'lnvestigaciò Biomèdica de Bellvitge (IDIBELL) > Articles publicats en revistes (Institut d'lnvestigaciò Biomèdica de Bellvitge (IDIBELL)) > View document

To access the full text documents, please follow this link: http://hdl.handle.net/2445/126171

dc.contributor.author	Vijai, Joseph
dc.contributor.author	Wang, Zhaoming
dc.contributor.author	Berndt, Sonja I.
dc.contributor.author	Skibola, Christine F.
dc.contributor.author	Slager, Susan L.
dc.contributor.author	Sanjosé Llongueras, Silvia de
dc.contributor.author	Melbye, Mads
dc.contributor.author	Glimelius, Bengt
dc.contributor.author	Bracci, Paige M.
dc.contributor.author	Conde, Lucia
dc.contributor.author	Birmann, Brenda M.
dc.contributor.author	Giovannucci, Edward
dc.contributor.author	Kraft, Peter
dc.contributor.author	Virtamo, Jarmo
dc.contributor.author	Smith, Alex
dc.contributor.author	Kane, Eleanor
dc.contributor.author	Roman, Eve
dc.contributor.author	Chiu, Brian C. H.
dc.contributor.author	Fraumeni, Joseph F.
dc.contributor.author	Wu, Xifeng
dc.contributor.author	Cerhan, James R.
dc.contributor.author	Offit, Kenneth
dc.contributor.author	Chanock, Stephen J.
dc.contributor.author	Rothman, Nathaniel
dc.contributor.author	Nieters, Alexandra
dc.contributor.author	Wang, Sophia S.
dc.contributor.author	Brooks-Wilson, Angela R.
dc.contributor.author	Lan, Qing
dc.contributor.author	Bakker, Paul I.W. de
dc.contributor.author	Vermeulen, Roel C. H.
dc.contributor.author	Portlock, Carol
dc.contributor.author	Ansell, Stephen M.
dc.contributor.author	Link, Brian K.
dc.contributor.author	Riby, Jacques
dc.contributor.author	North, Kari E.
dc.contributor.author	Gu, Jian
dc.contributor.author	Hjalgrim, Henrik
dc.contributor.author	Cozen, Wendy
dc.contributor.author	Becker, Nikolaus
dc.contributor.author	Teras, Lauren R.
dc.contributor.author	Spinelli, John J.
dc.contributor.author	Turner, Jenny
dc.contributor.author	Zhang, Yawei
dc.contributor.author	Purdue, Mark P.
dc.contributor.author	Giles, Graham G.
dc.contributor.author	Kelly, Rachel S.
dc.contributor.author	Zeleniuch-Jacquotte, Anne
dc.contributor.author	Ennas, Maria Grazia
dc.contributor.author	Monnereau, Alain
dc.contributor.author	Bertrand, Kimberly A.
dc.contributor.author	Albanes, Demetrius
dc.contributor.author	Lightfoot, Tracy
dc.contributor.author	Yeager, Meredith
dc.contributor.author	Chung, Charles C.
dc.contributor.author	Burdett, Laurie
dc.contributor.author	Hutchinson, Amy
dc.contributor.author	Lawrence, Charles
dc.contributor.author	Montalvan, Rebecca
dc.contributor.author	Liang, Liming
dc.contributor.author	Huang, Jinyan
dc.contributor.author	Ma, Baoshan
dc.contributor.author	Villano, Danylo J.
dc.contributor.author	Maria, Ann
dc.contributor.author	Corines, Marina
dc.contributor.author	Thomas, Tinu
dc.contributor.author	Novak, Anne J.
dc.contributor.author	Dogan, Ahmet
dc.contributor.author	Liebow, Mark
dc.contributor.author	Thompson, Carrie A.
dc.contributor.author	Witzig, Thomas E.
dc.contributor.author	Habermann, Thomas M.
dc.contributor.author	Weiner, George J.
dc.contributor.author	Smith, Martyn T.
dc.contributor.author	Holly, Elizabeth A.
dc.contributor.author	Jackson, Rebecca D.
dc.contributor.author	Tinker, Lesley F.
dc.contributor.author	Ye, Yuanqing
dc.contributor.author	Adami, Hans-Olov
dc.contributor.author	Smedby, Karin E.
dc.contributor.author	Roos, Anneclaire J. De
dc.contributor.author	Hartge, Patricia
dc.contributor.author	Morton, Lindsay M.
dc.contributor.author	Severson, Richard K.
dc.contributor.author	Benavente, Yolanda
dc.contributor.author	Boffetta, Paolo
dc.contributor.author	Brennan, Paul
dc.contributor.author	Foretova, Lenka
dc.contributor.author	Maynadie, Marc
dc.contributor.author	MCkay, James
dc.contributor.author	Staines, Anthony
dc.contributor.author	Diver, W. Ryan
dc.contributor.author	Vajdic, Claire M.
dc.contributor.author	Armstrong, Bruce K.
dc.contributor.author	Kricker, Anne
dc.contributor.author	Zheng, Tongzhang
dc.contributor.author	Holford, Theodore R.
dc.contributor.author	Severi, Gianluca
dc.contributor.author	Vineis, Paolo
dc.contributor.author	Ferri, Giovanni M.
dc.contributor.author	Ricco, Rosalia
dc.contributor.author	Miligi, Lucia
dc.contributor.author	Clavel, Jacqueline
dc.date	2018-11-16T09:44:21Z
dc.date	2018-11-16T09:44:21Z
dc.date	2015-01-08
dc.date	2018-07-24T12:35:07Z
dc.identifier.uri	http://hdl.handle.net/2445/126171
dc.format	application/pdf
dc.language.iso	eng
dc.publisher	Nature Publishing Group
dc.relation	Reproducció del document publicat a: https://doi.org/10.1038/ncomms6751
dc.relation	Nature Communications, 2015, vol. 6
dc.relation	https://doi.org/10.1038/ncomms6751
dc.rights	cc by (c) Vijai et al., 2015
dc.rights	info:eu-repo/semantics/openAccess
dc.rights	http://creativecommons.org/licenses/by/3.0/es/
dc.subject	Malaltia de Hodgkin
dc.subject	Cèl·lules B
dc.subject	Hodgkin's disease
dc.subject	B cells
dc.title	A genome-wide association study of marginal zone lymphoma shows association to the HLA region
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion
dc.description.abstract	Marginal zone lymphoma (MZL) is the third most common subtype of B-cell non-Hodgkin lymphoma. Here we perform a two-stage GWAS of 1,281 MZL cases and 7,127 controls of European ancestry and identify two independent loci near BTNL2 (rs9461741, P - 3.95 x 10(-15)) and HLA-B (rs2922994, P - 2.43 x 10(-9)) in the HLA region significantly associated with MZL risk. This is the first evidence that genetic variation in the major histocompatibility complex influences MZL susceptibility.

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