Title:
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Congenital transmission of Trypanosoma cruzi in Europe (Spain): a case report
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Author:
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Riera Lizandra, Ma. Cristina; Guarro, Anna; El Kassab, Houssein; Jorba, José Maria; Castro, Montserrat; Angrill, Roser; Gállego Culleré, M. (Montserrat); Fisa Saladrigas, Roser; Martin, Carmen; Lobato, Alejandro; Portús Vinyeta, Montserrat
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Other authors:
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Universitat de Barcelona |
Abstract:
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Here we report a documented case of congenital transmission of Trypanosoma cruzi from a Bolivian mother with chronic Chagas disease living in Spain. The serology and blood nested polymerase chain reaction (PCR) were positive for the mother, and amastigote forms were observed in histopathological study of the placenta and umbilical cord. Direct examination, culture, and nested PCR were positive in the blood of the neonate. At the age of 8 days, the neonate began treatment with 5-7.5 mg/kg/day of benznidazol, which was continued for 60 days. Direct examination, blood culture, and nested PCR were negative to T. cruzi 20 days after the start of treatment and remained negative 4 and 7 months thereafter. Serological tests were negative at 4 months. To detect congenital infection and initiate early treatment of infected newborns, protocols are required to detect Chagas disease in pregnant women who migrate from endemic to non-endemic areas. |
Subject(s):
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-Malaltia de Chagas -Malalties infeccioses -Embarassades -Espanya -Chagas' disease -Communicable diseases -Pregnant women -Spain |
Rights:
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(c) American Society of Tropical Medicine and Hygiene, 2006
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Document type:
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Article Article - Published version |
Published by:
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American Society of Tropical Medicine and Hygiene
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