Título:
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Dual Intermolecular Allylic C-H Functionalization within the Tetrasubstituted Alkene Scaffold
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Autor/a:
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Martínez, Claudio; Muñiz, Kilian
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Resum:
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Activation of chloramine‐T (TsNNaCl) with a Brønsted acid generates an active reagent for the double allylic C–H functionalization of tetrasubstituted alkenes in an intermolecular manner. The reaction generates a carbon–nitrogen and a carbon–chlorine bond, and proceeds with complete regio‐ and chemoselectivity. A total of 14 examples demonstrate the applicability of the dual C–H functionalization process. The mechanism involves the intermediacy of a 1,3‐butadiene derivative; 1,3‐butadienes can also be used directly as substrates. |
Fecha de creación:
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18-01-2018 |
Materia(s):
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Quimica |
Derechos:
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L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Páginas:
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1248 p. |
Tipo de documento:
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Artículo Artículo - Borrador |
DOI:
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10.1002/ejoc.201701624
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Editor:
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Eur. J. Org. Chem.
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Compartir:
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