Universitat de Barcelona
2015-10-30T16:20:57Z
2015-10-30T16:20:57Z
2015
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
Alanine aminotransferase (ALT) is a sensitive marker of dietary protein utilisation in fish. Three ALT isoforms (cALT1, cALT2 and mALT) encoded by two genes have been isolated from gilthead sea bream (Sparus aurata). Molecular characterization of ALT isozymes and gene promoters suggest involvement of cALT1 and mALT in postprandial use of dietary amino acids, while cALT2 seems associated to hepatic gluconeogenesis. Inhibition of hepatic cytosolic ALT activity stimulates pyruvate kinase and decreases the renewal rate of alanine in S. aurata. These findings point to ALT as a target to spare protein and improve catabolism of dietary carbohydrates in cultured fish.
Chapter or part of a book
Published version
English
Transferases; Suplements nutritius; Orada; Aqüicultura; Bioquímica; Biologia molecular; Transferases; Dietary supplements; Aquaculture; Biochemistry; Molecular biology; Sparus aurata
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 9, p. 133-148.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
