2013-12-20T11:19:18Z
2019-11-01T06:10:12Z
2010
2013-12-20T10:36:31Z
A simple, efficient protocol for the preparation of α-labeled aldehydes based on H/D exchange catalyzed by 4-(N,N-dimethylamino)pyridine or Et3N is described. High chemical yields and ratios of isotope incorporation were obtained even when small amounts (1 mmol) of aldehyde were used.
Article
Submitted version
English
Trastorns del metabolisme dels lípids; Bioquímica; Aldehids; Disseny de medicaments; Medicina nuclear; Lipid metabolism disorders; Biochemistry; Aldehydes; Drug design; Nuclear medicine
John Wiley & Sons
Versió preprint del document publicat a: http://dx.doi.org/10.1002/jlcr.1759
Journal of Labelled Compounds and Radiopharmaceuticals, 2010, vol. 53, num. 8, p. 556-558
http://dx.doi.org/10.1002/jlcr.1759
(c) John Wiley & Sons, 2010