Decoding the Conformation of Polylactic Acid in Block Copolymer Micelles

dc.contributor.author
Muñoz López, José María
dc.contributor.author
Tuveri, Gian Marco
dc.contributor.author
Barbieri, Valentino
dc.contributor.author
Basile, Marco
dc.contributor.author
Cosenza, V.
dc.contributor.author
Lorenz, Christian D.
dc.contributor.author
Ruiz-Perez, Lorena
dc.contributor.author
Battaglia, Giuseppe
dc.date.accessioned
2026-03-28T09:59:16Z
dc.date.available
2026-03-28T09:59:16Z
dc.date.issued
2026-03-27T09:27:48Z
dc.date.issued
2026-03-27T09:27:48Z
dc.date.issued
2026-01-28
dc.date.issued
2026-03-27T09:27:48Z
dc.identifier
0002-7863
dc.identifier
https://hdl.handle.net/2445/228558
dc.identifier
767404
dc.identifier.uri
https://hdl.handle.net/2445/228558
dc.description.abstract
Understanding how molecular features dictate the self-assembly of amphiphilic block copolymers into well-defined nanostructures is essential for the rational design of advanced soft materials. However, the large number of interdependent parameters involved, such as particle size, aggregation number, interfacial curvature, and molecular weight, makes it challenging to establish general design principles. Here we establish a scaling-based framework for PEG-<em>b</em>-PLA micelles with a fixed hydrophilic–hydrophobic ratio. Systematic variation of molecular weights enables precise control of micelle size and aggregation number, quantified by DLS, cryo-TEM, and MALS.
dc.format
5 p.
dc.format
application/pdf
dc.language
eng
dc.publisher
American Chemical Society
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1021/jacs.5c19227
dc.relation
Journal of the American Chemical Society, 2026, vol. 148, num.5, p. 4839-4843
dc.relation
https://doi.org/10.1021/jacs.5c19227
dc.rights
cc-by (c) Muñoz López, José María, et al., 2026
dc.rights
https://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Polimerització
dc.subject
Copolímers
dc.subject
Polymerization
dc.subject
Copolymers
dc.title
Decoding the Conformation of Polylactic Acid in Block Copolymer Micelles
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion


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