dc.contributor.author
Seemann, Myriam
dc.contributor.author
Campos Martínez, Narciso
dc.contributor.author
Rodríguez Concepción, Manuel
dc.contributor.author
Hoeffler, Jean François
dc.contributor.author
Grosdemange Billiard, Catherine
dc.contributor.author
Boronat i Margosa, Albert
dc.contributor.author
Rohmer, Michel
dc.date.accessioned
2026-01-23T20:09:52Z
dc.date.available
2026-01-23T20:09:52Z
dc.date.issued
2026-01-22T07:40:14Z
dc.date.issued
2026-01-22T07:40:14Z
dc.date.issued
2002-01-28
dc.date.issued
2026-01-22T07:40:14Z
dc.identifier
https://hdl.handle.net/2445/225922
dc.identifier.uri
https://hdl.handle.net/2445/225922
dc.description.abstract
In the bacterium Escherichiacoli, gcpE is an essential gene in the methylerythritol phosphate pathway for isoprenoid biosynthesis. Incubation of [1-3H]methylerythritol with an E. coli mutant defective in the gcpE gene resulted in the accumulation of [1-3H]methylerythritol 2,4-cyclodiphosphate. This suggests that the GCPE protein is involved in the further conversion of methylerythritol cyclodiphosphate into isoprenoids.
dc.format
application/pdf
dc.publisher
Elsevier Ltd.
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1016/S0040-4039(01)02269-9
dc.relation
Tetrahedron Letters, 2002, vol. 43, num.5, p. 775-778
dc.relation
https://doi.org/10.1016/S0040-4039(01)02269-9
dc.rights
(c) Elsevier Ltd., 2002
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Metabolisme microbià
dc.subject
Escheríchia coli
dc.subject
Microbial metabolism
dc.subject
Escherichia coli
dc.title
Isoprenoid biosynthesis via the methylerythritol phosphate pathway: accumulation of 2-C-methyl-erythritol2,4-cyclodiphosphate in a gcpE deficient mutant of Escherichia coli
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion
