dc.contributor.author
García Segura, Pol
dc.contributor.author
Malagelada Grau, Cristina
dc.date.issued
2025-04-28T13:47:46Z
dc.date.issued
2025-04-28T13:47:46Z
dc.date.issued
2023-01-20
dc.date.issued
2025-04-28T13:47:46Z
dc.identifier
https://hdl.handle.net/2445/220672
dc.description.abstract
The non-canonical functions of the transcription factor STAT3 have been poorly studied in comparison to its canonical mechanisms of gene expression activation. Here, Köhler et al. put the spotlight on a novel unconventional repressing mechanism of STAT3 over the REDD1 gene, named DDIT4. These findings are crucial to expand the knowledge of the stress-induced short-lived REDD1 protein that inactivates mTOR and the consequences of this fine-tuned regulation in the context of pathological conditions such as cancer or neurodegenerative diseases.
dc.format
application/pdf
dc.relation
Reproducció del document publicat a: https://doi.org/10.1111/febs.16727
dc.relation
The FEBS Journal, 2023, vol. 290, num.7, p. 1735-1739
dc.relation
https://doi.org/10.1111/febs.16727
dc.rights
cc by (c) García Segura, Pol et al., 2023
dc.rights
https://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Biomedicina)
dc.subject
Expressió gènica
dc.subject
Cèl·lules immunocompetents
dc.subject
Gene expression
dc.subject
Immunocompetent cells
dc.title
STAT3 and REDD1: an unconventional story of gene repression
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
