dc.contributor.author
Oliva Virgili, Rafael
dc.contributor.author
Castillo Corullón, Judit
dc.date.issued
2022-10-28T16:00:10Z
dc.date.issued
2022-10-28T16:00:10Z
dc.date.issued
2022-10-28T16:00:11Z
dc.identifier
https://hdl.handle.net/2445/190302
dc.description.abstract
Spermatogenesis involves extremely marked cellular, genetic and chromatin changes resulting in the generation of the highly specialized sperm cell. Proteomics allows the identification of the proteins that compose the spermatogenic cells and the study of their function. The recent developments in mass spectrometry (MS) have markedly increased the throughput to identify and to study the sperm proteins. Catalogs of thousands of testis and spermatozoan proteins in human and different model species are becoming available, setting up the basis for subsequent research, diagnostic applications and possibly the future development of specific treatments. The present review intends to summarize the key genetic and chromatin changes at the different stages of spermatogenesis and in the mature sperm cell and to comment on the presently available proteomic studies.
dc.format
application/pdf
dc.publisher
Wolters Kluwer - Medknow
dc.relation
Reproducció del document publicat a: https://doi.org/10.1038/aja.2010.65
dc.relation
Asian Journal of Andrology, 2011, vol. 13, num. 1, p. 24-30
dc.relation
https://doi.org/10.1038/aja.2010.65
dc.rights
cc-by-nc-sa (c) Oliva Virgili, Rafael et al., 2011
dc.rights
https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Biomedicina)
dc.subject
Espermatozoides
dc.subject
Espermatogènesi
dc.subject
Spermatogenesis
dc.title
Proteomics and the genetics of sperm chromatin condensation
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
