Título:
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Neuroprotection: A New Therapeutic Approach of Relapsing Remitting Multiple Sclerosis
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Autor/a:
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Espinosa-Parrilla, Juan F.; Pugliese, Marco; Mahy Gehenne, Josette Nicole; Rodríguez Allué, Manuel José
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Notas:
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Neurodegenerative changes occurring early from primary acute immune-mediated
inflammation support the hypothesis that multiple sclerosis (MS) is a complex disease.
Axonal loss progresses with the disease course and represents the principal driver of
disability. In this context, the pursuit of neuroprotective therapies in multiple sclerosis
provides new valid alternatives that could significantly impact on disease progression
and neurodegenerative changes, including the promotion of restoration of myelin
sheaths through the remyelination process. This chapter reviews promising drugs with
proposed neuroprotective or neuroregenerative effects that are currently approved or
in clinical trials for the treatment of multiple sclerosis. Although the chapter highlights
the diazoxide action on neuroinflammation and the results of a clinical trial with
this drug, the review also includes other molecules with oral or parenteral administration. |
Materia(s):
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-Esclerosi múltiple -Terapèutica -Multiple sclerosis -Therapeutics |
Derechos:
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cc by (c) Espinosa-Parrilla, Juan F. et al., 2016
http://creativecommons.org/licenses/by/3.0/es/
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Tipo de documento:
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Capítulo o parte de libro Artículo - Versión publicada |
Editor:
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IntechOpen
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Compartir:
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