Exploring Autophagy In Drosophila

Publication date

2018-09-04T14:03:32Z

2018-09-04T14:03:32Z

2017-09-01

2018-07-24T12:01:34Z

Abstract

Autophagy is a catabolic process in eukaryotic cells promoting bulk or selective degradation of cellular components within lysosomes. In recent decades, several model systems were utilized to dissect the molecular machinery of autophagy and to identify the impact of this cellular "self-eating" process on various physiological and pathological processes. Here we briefly discuss the advantages and limitations of using the fruit fly Drosophila melanogaster, a popular model in cell and developmental biology, to apprehend the main pathway of autophagy in a complete animal.

Document Type

Article


Published version

Language

English

Publisher

MDPI

Related items

Reproducció del document publicat a: https://doi.org/10.3390/cells6030022

Cells, 2017, vol. 6, num. 3

https://doi.org/10.3390/cells6030022

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Rights

cc by (c) Lörincz, Péter; Mauvezin, Caroline; Juhász, Gábor, 2017

http://creativecommons.org/licenses/by/3.0/es/