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dc.contributor.author | Bujanda, Luis |
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dc.contributor.author | Sarasqueta, Cristina |
dc.contributor.author | Lanas, Angel |
dc.contributor.author | Quintero, Enrique |
dc.contributor.author | Cubiella, Joaquín |
dc.contributor.author | Hernández, Vicent |
dc.contributor.author | Morillas, Juan D. |
dc.contributor.author | Perez-Fernández, T. |
dc.contributor.author | Salas, D. |
dc.contributor.author | Andreu, Montserrat |
dc.contributor.author | Carballo, F. |
dc.contributor.author | Bessa i Caserras, Xavier |
dc.contributor.author | Portillo, I. |
dc.contributor.author | Jover, Rodrigo |
dc.contributor.author | Balaguer Prunés, Francesc |
dc.contributor.author | Cosme, Ángel |
dc.contributor.author | Castells Garangou, Antoni |
dc.date | 2018-05-08T07:53:40Z |
dc.date | 2018-05-08T07:53:40Z |
dc.date | 2014-02-04 |
dc.date | 2018-05-08T07:53:41Z |
dc.identifier | 0007-0920 |
dc.identifier | 644873 |
dc.identifier | 24496455 |
dc.identifier.uri | http://hdl.handle.net/2445/122159 |
dc.description | Background: We aimed to evaluate whether oral anticoagulants (OACs) alter faecal immunochemical test (FIT) performance in average-risk colorectal cancer (CRC) screening. Methods: Individuals aged 50-69 years were invited to receive one FIT sample (cutoff 75 ng ml-1) between November 2008 and June 2011. Results: Faecal immunochemical test was positive in 9.3% (21 out of 224) of users of OAC and 6.2% (365 out of 5821) of non-users (P-trend ¼ 0.07). The positive predictive value (PPV) for advanced neoplasia (AN) in non-users was 50.4% vs 47.6% in users (odds ratio, 0.70; 95% CI, 0.3-1.8; P ¼ 0.5). The PPV for AN in OAC more antiplatelets (aspirin or clopidogrel) was 75% (odds ratio, 2; 95% CI, 0.4-10.8; P ¼ 0.4). Conclusions: Oral anticoagulant did not significantly modify the PPV for AN in this population-based colorectal screening program. The detection rate of advanced adenoma was higher in the combination OAC more antiplatelets. |
dc.format | 4 p. |
dc.format | application/pdf |
dc.language | eng |
dc.publisher | Cancer Research UK |
dc.relation | Reproducció del document publicat a: https://doi.org/10.1038/bjc.2014.38 |
dc.relation | British Journal of Cancer, 2014, vol. 110, num. 5, p. 1334-1337 |
dc.relation | https://doi.org/10.1038/bjc.2014.38 |
dc.rights | cc-by-nc-sa (c) Bujanda, Luis et al., 2014 |
dc.rights | http://creativecommons.org/licenses/by-nc-sa/3.0/es |
dc.rights | info:eu-repo/semantics/openAccess |
dc.subject | Càncer colorectal |
dc.subject | Anticoagulants (Medicina) |
dc.subject | Immunoquímica |
dc.subject | Colonoscòpia |
dc.subject | Estudi de casos |
dc.subject | Colorectal cancer |
dc.subject | Anticoagulants (Medicine) |
dc.subject | Immunochemistry |
dc.subject | Colonoscopy |
dc.subject | Case studies |
dc.title | Effect of oral anticoagulants on the outcome of faecal immunochemical test |
dc.type | info:eu-repo/semantics/article |
dc.type | info:eu-repo/semantics/publishedVersion |