dc.contributor.author
Sagasta, Amaia
dc.contributor.author
Saco, Adela
dc.contributor.author
Rodríguez-Carunchio, Leonardo
dc.contributor.author
Rull Ortuño, Antonio Ramón
dc.contributor.author
Ruiz, Ana
dc.contributor.author
Carrió, Ana
dc.contributor.author
Falcón Escobedo, Reynaldo
dc.contributor.author
Fernández Ruiz, Pedro Luis
dc.date.issued
2018-01-15T18:10:55Z
dc.date.issued
2018-01-15T18:10:55Z
dc.date.issued
2014-11-21
dc.date.issued
2018-01-15T18:10:55Z
dc.identifier
https://hdl.handle.net/2445/119034
dc.description.abstract
We report a unusual case of a 45-year-old woman with a massive metaplastic carcinoma of the breast with a complex admixture of components including giant pleomorphic cells, sarcomatoid areas, cysts with undifferentiated stratified epithelium, squamous carcinoma foci, high grade comedo-type ductal carcinoma in situ, high grade invasive carcinoma not otherwise specified (NOS) and foci with osseous differentiation. An extensive immunohistochemical panel showed expression of both epithelial and mesenchymal markers. The self-renewal marker SOX2 was expressed in different cell types, which was interpreted as a sign of the pluripotency what can in turn explain the diversity of histologic lineages present in this tumour.
dc.format
application/pdf
dc.publisher
Elsevier España
dc.relation
Reproducció del document publicat a: https://doi.org/10.1016/j.patol.2014.10.002
dc.relation
Revista Española de Patología, 2014, vol. 48, p. 170-175
dc.relation
https://doi.org/10.1016/j.patol.2014.10.002
dc.rights
(c) Sociedad Española de Anatomía Patológica y Sociedad Española de Citología, 2014
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Fonaments Clínics)
dc.subject
Càncer de mama
dc.title
Exuberant complex metaplastic carcinoma of the breast with sox2 expression: covering the full spectrum of ductal neoplasia of the breast
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
