dc.contributor.author
Gandioso, Albert
dc.contributor.author
Massaguer i Vall-llovera, Anna
dc.contributor.author
Villegas, Núria
dc.contributor.author
Salvans, Cándida
dc.contributor.author
Sánchez, Dani
dc.contributor.author
Brun Heath, Isabelle
dc.contributor.author
Marchán Sancho, Vicente
dc.contributor.author
Orozco López, Modesto
dc.contributor.author
Terrazas Martínez, Montserrat
dc.date.issued
2017-05-09T13:25:52Z
dc.date.issued
2018-12-31T06:10:19Z
dc.date.issued
2017-02-13
dc.date.issued
2017-05-09T13:25:52Z
dc.identifier
https://hdl.handle.net/2445/110712
dc.description.abstract
Despite the broad applicability of the Huisgen cycloaddition reaction, the click functionalization of RNAs with peptides remains still a challenge. Here we describe a straightforward method for the click functionalization of siRNAs with peptides of different size and complexity. Among them, a promising peptide carrier for the selective siRNA delivery into HER2+ breast cancer cell lines.
dc.format
application/pdf
dc.publisher
Royal Society of Chemistry
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1039/C6CC10287E
dc.relation
Chemical Communications, 2017, vol. 53, num. 19, p. 2870-2873
dc.relation
https://doi.org/10.1039/C6CC10287E
dc.rights
(c) Gandioso et al., 2017
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Química Inorgànica i Orgànica)
dc.subject
Càncer de mama
dc.subject
Cèl·lules canceroses
dc.title
Efficient siRNA-peptide conjugation for specific targeted delivery into tumor cells
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion
