Cortical microstructural imaging from diffusion MRI: towards sensitive biomarkers for clinical trials

Abstract

This scientific commentary refers to ‘Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer’s disease’ by Spotorno et al. (https://doi.org/10.1093/brain/awad428).

E.R.-V. is supported by research grants from the Stockholm County Council-Karolinska Institutet regional agreement on medical training and clinical research (ALF grants FoUI-960437, FoUI-975492), Neuroförbundet (F2022-0036, F2023-0049), Demensfonden, Alzheimerfonden (AF-939647, AF-968569), Åhlén foundation, Stiftelsen för Gamla Tjänarinnor, Gun and Bertil Stohnes Foundation, and Karolinska Institutet (KI Fonder). V.M. received funding from a Juan de la Cierva fellowship (JDC2022-048492-I) from the Ministry of Science of the Spanish Government. C.G. received funding from the Swedish FTD Initiative-Schörling Foundation; Swedish Research Council Dnr 529-2014-7504, 2019-0224, 2015-02926, 2018-02754; Alzheimerfonden; Hjärnfonden; Demensfonden and Region Stockholm ALF-project.

Peer Reviewed

Postprint (author's final draft)