Centres de Recerca de Catalunya (CERCA)
2025-12-12
We report a series of endo-functionalized molecular receptors based on a calix[4]pyrrole scaffold, which exhibit Hydrogen Atom Transfer (HAT) reactivity towards free-radicals (e.g., peroxyl radicals). The chemical structure and shape of the molecular receptors affect the affinity towards free-radicals, while host-guest interactions are used to fine-tune the HAT reactivity, mimicking enzyme modulation in biological systems.
Article
Accepted version
English
8 p.
ACS Publications
M.P. thanks Government of Catalunya for a Beatriu de Pinós 2021 grant (2021 BP 00028)
Gobierno de España MICIU/AEI/10.13039/501100011033, FEDER/UE (PID2023-149233NB-IOO) and MICIU/AEI/10.13039/501100011033 (CEX2024-001469-S)
CERCA Programme/Generalitat de Catalunya
AGAUR (2021 SGR 00851)
European Union - NextGenerationEU under the National Recovery and Resilience Plan (PNRR) - Mission 4 Education and research - Component 2 From research to business - Investment 1.1 Notice Prin 2022 - DD N. 104 del 2/2/2022, from PRIN20227XZKBY - Superoxide responsive redox-active systems and nano smart materials to target ferroptosis – FEROX - CUP J53D23008550006
W.P. acknowledges support from China Scholarship Council (CSC)
Attribution 4.0 International
Papers [1286]
