IQS: Recent submissions
Now showing items 441-460 of 794
Versatile Supramolecular Complex for Targeted Antimicrobial Photodynamic Inactivation
We report the development of a supramolecular structure endowed with photosensitizing properties and targeting capability for antimicrobial photodynamic inactivation. Our synthetic strategy uses the tetrameric bacterial ...
Photodynamic synergistic effect of pheophorbide a and doxorubicin in combined treatment against tumoral cells
A combination of therapies to treat cancer malignancies is at the forefront of research with the aim to reduce drug doses (ultimately side effects) and diminish the possibility of resistance emergence given the multitarget ...
Big data in multi-block data analysis: An approach to parallelizing Partial Least Squares Mode B algorithm
Partial Least Squares (PLS) Mode B is a multi-block method and a tightly coupled algorithm for estimating structural equation models (SEMs). Describing key aspects of parallel computing, we approach the parallelization of ...
Chelating properties of tripeptide-9 citrulline
Tripeptide-9 Citrulline (INCI name) is a peptide with skin care properties, used for cosmetic applications. In order to elucidate its mechanism of action in the chemical pathways that involve metal ions, its ability to ...
Assessing amphiphilic ABAB Zn(II) Phthalocyanines with enhanced photosensitization abilities in In Vitro photodynamic therapy studies against cancer
We have previously demonstrated that singlet oxygen photosensitization abilities of Zn(II) phthalocyanines (Zn(II)Pcs) are enhanced through α-functionalization with bulky fluorinated substituents (i.e., bis(trifluoromethyl)phenyl ...
Additive Manufacturing Gyroid Structures Used as Crash Energy Management
Gyroid-like structures are promising in terms of energy absorption levels. Due to additive manufacturing, they can now be manufactured and verified for different functions. In this article, it has been proven that a Gyroid ...
Influence of the carbon incorporation on the mechanical properties of TiB2 thin films prepared by HiPIMS
Nanostructured TiB2 and TiBC thin films with carbon contents up to 11 at. % were prepared by physical vapor deposition using high power impulse magnetron sputtering (HiPIMS) technology. The influence of carbon incorporation ...
Novel grafted electrochemical interface for covalent glucose oxidase immobilization using reactive pentafluorophenyl methacrylate
One of the most important factors for the proper functioning of enzymatic electrochemical biosensors is the enzyme immobilization strategy. In this work, glucose oxidase was covalently immobilized using pentafluorophenyl ...
Characterization of duplex coating system (HVOF + PVD) on light alloy substrates
Light metals such as aluminium or magnesium alloys play an important role in many different industrial applications. However, aluminium and especially magnesium alloys show relatively poor resistance to sliding wear, low ...
Different Modelling Purposes
How one builds, checks, validates and interprets a model depends on its ‘purpose’. This is true even if the same model code is used for di erent purposes. This means that a model built for one purpose but then used for ...
Innovative light sources for phototherapy
The use of light for therapeutic purposes dates back to ancient Egypt, where the sun itself was an innovative source, probably used for the first time to heal skin diseases. Since then, technical innovation and advancement ...
Simple generation of human induced pluripotent stem cells using poly-β-amino esters as the non-viral gene delivery system
Reprogramming of somatic cells to induced pluripotent stem (iPS) cells can be achieved by the delivery of a combination of transcription factors, including Oct4, Sox2, Klf4, and c-Myc. Retroviral and lentiviral vectors are ...
Predictors of patronage intentions towards ‘green’ hotels in an emerging tourism market
Hotel administrations in emerging tourism markets do not invest in environmental conservation because of low confidence in that such investment will drive customer patronage. Empirical evidence is required to showcase what ...
Role of infill parameters on the mechanical performance and weight reduction of PEI Ultem processed by FFF
In comparison with conventional manufacturing technologies, Fused Filament Fabrication (FFF) offers countless benefits. It broadens the horizons of the design of structural components with high geometrical complexity, and ...
When Unsuspected Crystallinity Ruins Biological Testing in Early Discovery: A Case Study
The impact of the crystalline or amorphous structure of a solid on the solubility and pharmacokinetic properties of a drug candidate is always considered by the pharmaceutical industry during the development of a new drug; ...
An empirical analysis of the curvilinear relationship between slack and firm performance
This study performs an in-depth analysis of the curvilinear relationship between slack and future firm performance. Using a sample of US firms, we analyze the influence of three indicators of absorbed and unabsorbed slack ...
Audit firm tenure and qualified opinions: new evidence from Spain
The 2010 Green Paper on Audit Policy by the European Commission has explicitly questioned the sufficiency of audit rotation rules established by European Union Members to guarantee auditor independence. In addition, the ...
Viscoelastic models revisited: characteristics and interconversion formulas for generalized Kelvin–Voigt and Maxwell models
Generalized Kelvin–Voigt and Maxwell models using Prony series are some of the most well-known models to characterize the behavior of polymers. The simulation software for viscoelastic materials generally implement only ...
Immune responses associated with mpox viral clearance in men with and without HIV in Spain: a multisite, observational, prospective cohort study
Background: Since the emergence of the global mpox outbreak in May, 2022, more than 90 000 cases have been diagnosed across 110 countries, disproportionately affecting people with HIV. The durability of mpox-specific ...
The evolution of a study and research path in Statistics
We present the organisation of a first course in statistics for Business Administration degree students, which includes a study and research path (SRP) as an inquiry-based teaching proposal. The paper aims to summarise the ...
