Institut de Nanociència i Nanotecnologia (IN2UB): Enviaments recents
Ara mostrant els elements 201-220 de 375
Magnetic Nanoparticles Cross the Blood-Brain Barrier: When Physics Rises to a Challenge
The blood-brain barrier is a physical and physiological barrier that protects the brain from toxic substances within the bloodstream and helps maintain brain homeostasis. It also represents the main obstacle in the treatment ...
Dynamical shapes of droplets of cyclodextrin/surfactants solutions
We present a series of experiments with droplets of aqueous cyclodextrin-surfactant solutions, in which the volume is reduced after the equilibrium spherical shape is reached. The fnal shape of the drop after this perturbation ...
The dynamics of shapes of vesicle membranes with time dependent spontaneous curvature
We study the time evolution of the shape of a vesicle membrane under time-dependent spontaneous curvature by means of phase-field model. We introduce the variation in time of the spontaneous curvature via a second field ...
Development of a New largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies.
The resolution of the three-dimensional structure of infectious prions at the atomic level is pivotal to understand the pathobiology of Transmissible Spongiform Encephalopathies (TSE), but has been long hindered due to ...
Development, cytotoxicity and eye irritation profile of a new sunscreen formulation based on benzophenone-3-poly(ε-caprolactone) nanocapsules.
The objective of this work was to characterize the toxicological profile of a newly developed sunscreen formulation based on polymeric nanocapsules (NCs) loading benzophenone-3 (BZP3). NCs composed of poly(ε-caprolactone) ...
Unraveling the Formation of Ternary AgCuSe Crystalline Nanophases and Their Potential as Antibacterial Agents
AgCuSe nanoparticles could contribute to the growth of strongly light-absorbing thin films and solids with fast ion mobility, among other potential properties. Nevertheless, few methods have been developed so far for the ...
Integrated Strategy toward Self-Powering and Selectivity Tuning of Semiconductor Gas Sensors
Inorganic conductometric gas sensors struggle to overcome limitations in high power consumption and poor selectivi-ty. Herein, recent advances in developing self-powered gas sensors with tunable selectivity are introduced. ...
Multifunctional Serine Protease Inhibitor-Coated Water-Soluble Gold Nanoparticles as a Novel Targeted Approach for the Treatment of Inflammatory Skin Diseases
The overexpression and increased activity of the serine protease Kallikrein 5 (KLK5) is characteristic of inflammatory skin diseases such as Rosacea. The use of inhibitors of this enzyme¿such as 4-(2-aminoethyl)benzenesulfonyl ...
A genomics approach identifies selective effects of trans-resveratrol in cerebral cortex neuron and glia gene expression
The mode of action of trans-resveratrol, a promising lead compound for the development of neuroprotective drugs, is unknown. Data from a functional genomics study were retrieved with the aim to find differentially expressed ...
Novel strategies against cancer: dexibuprofen loaded nanostructured lipid carriers
The aim of this work was to design innovative nanostructured lipid carriers (NLCs) for the delivery of dexibuprofen (DXI) as an antiproliferative therapy against tumoral processes, and overcome its side effects. DXI-NLC ...
Co-Ni-carbon flexible composite fibres for directional magnetic actuation
Flexible microcomponents are being widely employed in the microelectronic industry; however; they suffer from a lack of complex movement. To address this problem, we have developed flexible, electrically conductive, magnetic ...
Role of c-Jun N-Terminal Kinases (JNKs) in Epilepsy and Metabolic Cognitive Impairment
Previous studies have reported that the regulatory function of the different c-Jun N-terminal kinases isoforms (JNK1, JNK2, and JNK3) play an essential role in neurological disorders, such as epilepsy and metabolic-cognitive ...
Colistin treatment causes neuronal loss and cognitive impairment via ros accumulation and neuronal plasticity alterations
The rise of antimicrobial resistance has made necessary the increase of the antibacterial arsenal against multidrug-resistant bacteria. In this context, colistin has re-emerged as a first-line antibiotic in critical ...
Characterisation of the enzymes involved in the diol synthase metabolic pathway in Pseudomonas aeruginosa
This study is the first attempt to report the biochemical characterisation of the 10S-dioxygenase (10S-DOX) and 7S, 10S-diol synthase (7,10-DS). Both enzymes showed similar pH profiles with 10S-DOX presenting the highest ...
Effect of E1(64-81) hepatitis G peptide on the in vitro interaction of HIV-1 Fusion Peptide with membrane models
One way to gain information about the fusogenic potential of virus-derived synthetic peptides is to examine their interfacial properties and subsequently to study them in monolayers and bilayers. Here, we characterize the ...
First Order Alignment Transition in an Interfaced Active Nematic
We investigate experimentally the dynamic phase transition of a two-dimensional active nematic layer interfaced with a passive liquid crystal. Under a temperature ramp that leads to the transition of the passive liquid ...
Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a ...
Rotating mixed 3He-4He nanodroplets
Mixed 3He−4He droplets may acquire angular momentum during their passage through the nozzle of the experimental apparatus, cooling down and undergoing isotopic segregation, developing a 3He crust surrounding a superfluid ...
Transport and Assembly of Magnetic Surface Rotors
This minireview focuses on recent advances with surface magnetic rotors, namely field-responsive spherical or anisotropic microparticles that translate close to, or are embedded in a confining surface. The application of ...
Thin-Film Stabilization of a Ferroelectric Orthorhombic α Pr2WO6 Polymorph
A new orthorhombic α-Pr2WO6 (PrWO) polymorph with a = 16.57(5) Å, b = 5.52(5) Å and c= 8.73(1) Å, isostructural to α-La2WO6 and α-Nd2WO6, has been stabilized in the form of thin film by pulsed laser deposition on (001)-oriented ...
