Institut de Nanociència i Nanotecnologia (IN2UB): Enviaments recents
Ara mostrant els elements 61-80 de 375
Bidirectional zigzag growth from clusters of active colloidal shakers
Driven or self-propelling particles moving in viscoelastic fluids recently emerged as a novel class of active systems showing a complex yet rich set of phenomena due to the non-Newtonian nature of the dispersing medium. ...
Heterodinuclear [Co-Ln] complexes of semicarbazide-arm bearing ligand: synthesis from the cleavage of starting [Co-Co] complex, structures and magnetic properties
The heterometallic bridging potential of the anion of 1-(2-hydroxy-3-methoxybenzylidene)-semicarbazide (HL) to CoIIand four 4f ions was examined during a 4f ion coordination-driven cleavageof [Co2(m-OH2)(O2CCMe3)4(HO2CCM ...
Ex Vivo Permeation of Carprofen Vehiculated by PLGA Nanoparticles through Porcine Mucous Membranes and Ophthalmic Tissues
(1) Background: Carprofen (CP), 2-(6-chlorocarbazole) propionic acid, is used as an anti-inflammatory, analgesic and anti-pyretic agent and it belongs to the family of non-steroidal anti-inflammatory drugs (NSAIDs). CP has ...
Effects of ITO based back contacts on Cu(In,Ga)Se2 thin films, solar cells, and mini-modules relevant for semi-transparent building integrated photovoltaics
This study presents the results of the development of semi-transparent Cu(In,Ga)Se2 (CIGSe) mini-modules for the application in building integrated photovoltaics (BIPV). Applying in-situ X-ray diffraction in real-time ...
Steric hindrance, ligand ejection and associated photocytotoxic properties of ruthenium(II) polypyridyl complexes
Two ruthenium(II) polypyridyl complexes were prepared with the {Ru(phen)2}2+ moiety and a third sterically non-hindering bidentate ligand, namely 2,2'-dipyridylamine (dpa) and N-benzyl-2,2'-dipyridylamine (Bndpa). Hence, ...
Chondroitin Sulfate for cartilage regeneration, administered topically using a nanostructured formulation
In the pharmaceutical sector, solid lipid nanoparticles (SLN) are vital for drug delivery incorporating a lipid core. Chondroitin sulfate (CHON) is crucial for cartilage health. It is often used in osteoarthritis (OA) ...
Novel strategies enhancing endodontic disinfection: antibacterial biodegradable calcium hydroxide nanoparticles in an ex vivo model
<span style="color:rgb( 33 , 33 , 33 )">Due to the high failure rates associated to endodontic disinfection, this study aimed to investigate the antibacterial properties of poly(lactic-co-glycolic acid) (PLGA) nanoparticles ...
Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a ...
Deu anys de seguiment demogràfic i genètic d'Stachys maritima a Catalunya (2001-2010). Implicacions per a un pla de recuperació.
Ten years of demographic and genetic monitoring of Stachys maritima in Catalonia (2001-2010). Implications for a recovery plan.- Stachys maritima is a species typical of the coastal dunes, with a wide distribution within ...
Human skin permeation studies with PPARγ agonist to improve its permeability and efficacy in inflammatory processes
Rosacea is the most common inflammatory skin disease. It is characterized by erythema, inflammatory papules and pustules, visible blood vessels, and telangiectasia. The current treatment has limitations and unsatisfactory ...
Memantine loaded PEGylated biodegradable nanoparticles for the treatment of glaucoma
Glaucoma is a multifactorial neurodegenerative disease associated with retinal ganglion cells (RGC) loss. Increasing reports of similarities in glaucoma and other neurodegenerative conditions have led to speculation that ...
The Involvement of Peripheral and Brain Insulin Resistance in Late Onset Alzheimer's Dementia
Nowadays, Alzheimer's disease (AD) is a severe sociological and clinical problem. Since it was first described, there has been a constant increase in its incidence and, for now, there are no effective treatments since ...
Multifunctional Serine Protease Inhibitor-Coated Water-Soluble Gold Nanoparticles as a Novel Targeted Approach for the Treatment of Inflammatory Skin Diseases
The overexpression and increased activity of the serine protease Kallikrein 5 (KLK5) is characteristic of inflammatory skin diseases such as Rosacea. The use of inhibitors of this enzyme¿such as 4-(2-aminoethyl)benzenesulfonyl ...
Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization
Background: Memantine, drug approved for moderate to severe Alzheimer's disease, has not shown to be fully efective. In order to solve this issue, polylactic-co-glycolic (PLGA) nanoparticles could be a suitable solution ...
PEGylated PLGA nanospheres optimized by design of experiments for ocular administration of dexibuprofen in vitro, ex vivo and in vivo characterization
Dexibuprofen-loaded PEGylated PLGA nanospheres have been developed to improve the biopharmaceuti-cal profile of the anti-inflammatory drug for ocular administration. Dexibuprofen is the active enantiomerof ibuprofen and ...
Cationic supramolecular hydrogels for overcoming the skin barrier in drug delivery
A cationic bis‐imidazolium‐based amphiphile was used to form thermoreversible nanostructured supramolecular hydrogels incorporating neutral and cationic drugs for the topical treatment of rosacea. The concentration of the ...
Role of c-Jun N-Terminal Kinases (JNKs) in Epilepsy and Metabolic Cognitive Impairment
Previous studies have reported that the regulatory function of the different c-Jun N-terminal kinases isoforms (JNK1, JNK2, and JNK3) play an essential role in neurological disorders, such as epilepsy and metabolic-cognitive ...
Suspended Planar-Array Chips for Molecular Multiplexing at the Microscale
Suspended planar-array (SPA) chips embody millions of individual miniaturized arrays to work in extremely small volumes. Here, the basis of a robust methodology for the fabrication of SPA silicon chips with on-demand ...
Strategies against β-amyloid protein as therapeutics in Alzheimer's disease
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
Shogaol-huprine hybrids: Dual antioxidant and anticholinesterase agents with beta-amyloid and tau anti-aggregating properties
Multitarget compounds are increasingly being pursued for the effective treatment of complex diseases. Herein, we describe the design and synthesis of a novel class of shogaol<br>huprine hybrids, purported to hit several ...
