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IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer: Recent submissions

Now showing items 21-40 of 3164

    Unveiling Drug-Induced Autoimmune-Like Hepatitis in Autoimmune Hepatitis Patients: A Multicenter Retrospective Study 

    Arvaniti, Pinelopi; Olivas, Ignasi; Pascual-Dapena, Ana; Riveiro-Barciela, Mar; Esteban, Paula; Aguilar, Anna; Perez-Medrano, Indhira; Horta, Diana; Caballero Marcos, Arancha; Salcedo, Magdalena; Conde, Isabel; Gomez, Elena; Castello, Inmaculada; Barbara, Jesus Santa; Diaz-Gonzalez, Alvaro; Del Barrio, Maria; Lorente, Sara; Mateos, Beatriz; Arencibia, Ana; Jimenez, Miguel; Cuenca, Paqui; Bernal-Monterde, Vanesa; Fernandez, Eva-Maria; Rodríguez Tajes, Sergio; Pocurull, Anna; Hernandez Evole, Helena; Forns Bernhardt, Xavier; Andrade, Raul J; Londoño Hurtado, María Carlota (Publication date: 2026-02-27)

    Background and Aims Acute or chronic exposure to drugs or herbal and dietary supplements (HDS) can cause drug-induced autoimmune-like hepatitis (DI-ALH), a self-limiting condition resembling autoimmune hepatitis (AIH). We ...

    Higher seroprevalence of hepatitis E virus in autoimmune hepatitis: Role of false-positive antibodies 

    Llovet, Laura Patricia; Londoño, María Carlota; Gratacós Ginès, Jordi; Ortiz, Oswaldo; Rodriguez Tajes, Sergio; Lens García, Sabela; Reverter, Enric; Ruiz Ortiz, Estíbaliz; Costa Faidella, Jordi; Viñas, Odette; Forns, Xavier; Parés Darnaculleta, Albert (Publication date: 2026-02-27)

    Background and aims Recent studies have found an increase in the seroprevalence of hepatitis E virus (HEV) infection in patients with autoimmune hepatitis (AIH). We aimed to assess the prevalence of positive anti-HEV IgM ...

    Presentation and Outcomes of Pregnancy in Patients With Autoimmune Hepatitis 

    Llovet LP; Horta D; Eliz MG; Berenguer M; Fábrega E; Sáez-Royuela F; Garcia-Retortillo M; Torrijos YS; Romero-Gomez M; Fernandez C; Domínguez EG; Parés Darnaculleta, Albert; Londoño Hurtado, María Carlota (Publication date: 2026-02-26)

    Autoimmune hepatitis (AIH) frequently affects women of childbearing age in whom the desire to have a family raises the question regarding the potential risks for the fetus and the mother. The information on AIH in pregnant ...

    Determinants of HBsAg Loss After Nucleos(t)ide Discontinuation in a Prospective Cohort of HBeAg-Negative Caucasian Patients 

    Pocurull Aparicio, Anna; Broquetas, Teresa; Hoyas, Elena; Rodriguez, Manuel; Miquel, Mireia; Rodriguez, Mercedes; Roig, Clara Amiama; Herms Rubió, Queralt; Rodríguez Tajes, Sergio; Garcia-Samaniego, Javier; Suarez, Emilio; Buti, Maria; Forns Bernhardt, Xavier; Carrion, Jose A; Lens García, Sabela (Publication date: 2026-02-27)

    Introduction: Nucleos(t)ide analogues (NAs) discontinuation in HBeAg-negative chronic hepatitis B (CHB) aims at increasing functional cure rates. However, clinical outcomes and predictive factors for HBsAg loss or re-treatment ...

    Influence of language barrier and cultural background in hepatitis B disease knowledge in a Chinese community of Spain 

    Pocurull Aparicio, Anna; Collazos Clemente, Cristina; Miralpeix Vissi, Anna; Tapias, Laura; Wang, Tao; Moreta, Maria Jose; Mariño Mendez, Zoe; Lens García, Sabela; Forns Bernhardt, Xavier (Publication date: 2026-02-27)

    Introduction Hepatitis B infection (HBV) is prevalent in China. Due to language barriers and cultural differences, it is not always straightforward to evaluate disease knowledge in liver clinics. We aimed to assess the ...

    Vestibulo-ocular reflex assessed with Video Head Impulse Test in children with Vestibular Migraine: Our experience 

    Rodríguez-Villalba, Rosana; Caballero Borrego, Miguel; Villarraga, Vanessa; de Jesus, Victoria Rivero; Claveria, Maria Antonia; Haag, Oliver (Publication date: 2026-02-26)

    Vestibular Migraine in children can mimic other disorders, especially at presentation. Outcome is hard to predict and management may be challenging due to the fact that many of the patients are too young to describe their ...

    Deep Medullary Vein Integrity and Relationships with Small Vessel Disease and Interstitial Diffusivity Measures in Patients with a Recent Small Subcortical Infarct 

    Brenlla, Carla; Sozzi, Caterina; Girona, Andres; Martinez Quintanilla Martinez, Jordi; Laredo Gregorio, Carlos; Rodríguez Vázquez, Alejandro; Amaro Delgado, Sergio; Renú Jornet, Arturo; Doncel-Moriano Cubero, Antonio; Llull Estrany, Laura; Urra Nuin, Xabier; Rudilosso, Salvatore; Chamorro Sanchez, Ángel (Publication date: 2026-02-27)

    BACKGROUND AND PURPOSE: The role of the venous compartment in cerebral small vessel disease has yet to be fully understood. As such, we evaluated how deep medullary vein (DMV) integrity relates to MRI-based small vessel ...

    European Society for Organ Transplantation Consensus Statement on Biomarkers in Liver Transplantation 

    Berenguer M.; de Martin E.; Hessheimer, Amelia Judith; Levitsky J.; Maluf D.G.; Mas V.R.; Selzner N.; Hernandez Evole, Helena; Lutu A.; Wahid N.; Zubair H. (Publication date: 2026-02-25)

    Currently, one-year survival following liver transplantation (LT) exceeds 90% in large international registries, and LT is considered definitive treatment for patients with end-stage liver disease and liver cancer. Recurrence ...

    Alcohol-associated liver disease: Natural history, management and novel targeted therapies 

    Alvarado-Tapias, Edilmar; Pose Mendez, Elisa; Gratacós Ginès, Jordi; Clemente-Sanchez, Ana; López Pelayo, Hugo; Bataller Alberola, Ramon (Publication date: 2026-02-25)

    Alcohol consumption is a leading cause of preventable morbidity and mortality worldwide and the primary cause of advanced liver disease. Alcohol use disorder is a chronic, frequently relapsing condition characterized by ...

    Isolated IgG elevation in patients with persistently normal transaminases does not affect the outcome of autoimmune hepatitis. 

    Díaz-Gonzalez A; Schregel I; Carballo L; Álvarez-Navascués C; Frisancho-Morales E; Miquel M; Retortillo MG; Gomez J; Horta D; Mateos B; Engel B; Volmer F; Barrio MD; Rodríguez-Tajes S; Olivas I; Hartl J; Gonzalez CA; Hernández-Guerra M; Castelló I; Pérez-Medrano I; González-Santiago JM; Arencibia A; Gómez A; Rodríguez-Perálvarez M; Crespo J; Sala M; Salcedo M; Barreira-Díaz A; Riveiro-Barciela M; Taubert R; Schramm C; Londoño MC (Publication date: 2026-02-25)

    The goal of treatment for autoimmune hepatitis is to achieve a complete biochemical response, defined as normalization of transaminases and immunoglobulin G (IgG) levels. Recent data suggest that IgG normalization does not ...

    Noninvasive Prediction of Outcomes in Autoimmune Hepatitis-Related Cirrhosis 

    Llovet LP; Gratacós Ginès, Jordi; Tellez L; Gómez-Outomuro A; Navascués CA; Riveiro-Barciela M; Vinuesa R; Gomez-Camarero J; Garcia-Retortillo M; Díaz-Fontenla F; Salcedo M; Garcia-Eliz M; Horta D; Guerrero Hernandez, Martina; Rodríguez-Perálvarez M; Fernandez-Rodriguez C; Albillos, Agustín; G-Abraldes J; Parés Darnaculleta, Albert; Londoño Hurtado, María Carlota (Publication date: 2026-02-25)

    The value of noninvasive tools in the diagnosis of autoimmune hepatitis (AIH)-related cirrhosis and the prediction of clinical outcomes is largely unknown. We sought to evaluate (1) the utility of liver stiffness measurement ...

    Liver stiffness measurement predicts clinical outcomes in autoimmune hepatitis 

    Torres Riera, Sonia; Olivas Alberch, Ignasi; Arvaniti, Pinelopi; Gabeta, Stella; Torres Berlanga, Sandra; Del Barrio, Maria; Diaz-Gonzalez, Alvaro; Esteban, Paula; Riveiro-Barciela, Mar; Mauro, Ezequiel Matías; Rodríguez Tajes, Sergio; Zachou, Kalliopi; Dalekos, George N; Londoño Hurtado, María Carlota (Publication date: 2026-02-25)

    Background & Aims: Liver stiffness measurement (LSM) has been shown to adequately predict outcomes in patients with liver disease. However, the value of LSM as a predictor of disease progression in autoimmune hepatitis ...

    A cross-sectional pilot study to define anal cancer risk factors in HIV-positive solid organ transplant recipients. 

    Fuertes, Irene; Chivite, Ivan; Cranston, R.D.; Sánchez, Emilia; Lazzari, Elisa de; Marimon, Lorena; Ordi i Majà, Jaume; Miró Meda, José M. (José María), 1956-; Blanco, José L. (Publication date: 2026-02-25)

    Background HIV-positive organ transplant recipients are at high risk of anal cancer, but there are no data on the prevalence of high-risk human papillomavirus (hr-HPV) or anal dysplasia, in this population. Objective To ...

    Infective endocarditis after transcatheter versus surgical aortic valve replacement 

    Panagides, Vassili; Cuervo Requena, Guillermo; Llopis Pérez, Jaime; Abdel-wahab, Mohamed; Mangner, Norman; Habib, Gilbert; Regueiro, Ander; Mestres, Carlos A.; Tornos, Pilar; Durand, Eric; Selton Suty, Christine; Ihlemann, Nikolaj; Bruun, Niels E; Urena, Marina; Cecchi, Enrico; Thiele, Holger; Durante Mangoni, E.; Pellegrini, Costanza; Eltchaninoff, Helene; Athan, Eugene; Søndergaard, Lars; Linke, Axel; Tattevin, Pierre; Val, David del; Quintana, Eduard; Chu, Vivian; Rodés Cabau, Josep; Miró Meda, José M. (José María), 1956-; TAVI Infective Endocarditis International Registry and ICE Investigators (Publication date: 2026-02-24)

    Abstract Background Scarce data are available comparing infective endocarditis (IE) following surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR). This study aimed to compare the ...

    OAS1 and OAS3 genetic variants enhance inflammatory responses to SARS-CoV-2 

    DeDiego, Marta L.; López-Fernández-Sobrino, Raúl; Pedragosa, Jordi; López-García, Darío; Nogales, Aitor; Durbán, Jordi; Cardona, Fernando; Llucià-Carol, Laia; Rivero, Vanessa; Vazquez-Utrilla, Paula; Palomo Sanchez-Grande, Laura; Cobo, Miriam; Lloret, Lara; Márquez-Kisinousky, Leonardo; Ruiz-Jaén, Francisca; Lozano, Francisco; Sibila, Oriol; Faner, Rosa; Castro Rebollo, Pedro; Domingo, Carlos; Robles, Verónica; Bedini, Josep L.; Rico, Verónica; Aguero, Daiana; Soriano, Alex; Martín Nalda, Andrea; Parra Martínez, Alba; Colobran, Roger; Soler-Palacín, Pere; Serra-Llovich, Alexandre; Dietl, Beatriz; Arranz, M. Jesús; Dalmau, David; Signes-Costa, Jaime; Gil-Carbonell, Joan; Todolí, José; Martínez, Jacobo; Rojo, Silvia; Fiz-López, Aida; Arribas, Elisa; Cal-Sabater, Paloma; Bernado, David; Vogel, Marina; Wiemann, Stefan; Abolhassani, Hassan; Pan-Hammarström, Qiang; Pujol, Aurora; COVID Human Genetic Effort; Su, Helen C.; Lee, Danyel; Zhang, Shen-Ying; Casanova, Jean-Laurent; Fernández-Cadenas, Israel; Pérez-Tur, Jordi; Planas, Anna M. (Publication date: 2026-02-24)

    Recessive deficiency in 2′ ,5′ -oligoadenylate synthetase (OAS) or RNase L can cause systemic inflammation in children with SARS-CoV-2 infection, but its role in adult respiratory disease is unclear. We analyzed rare ...

    A contemporary picture of coagulase-negative staphylococcal endocarditis: a Nationwide GAMES Cohort Study 

    Palom Grau, Clara; Cuervo Requena, Guillermo; Muñoz, Patricia; Marín, Mercedes; Martínez Sellés, Manuel; González Ramallo, Víctor; Alarcón, Aristides de; Poyato Borrego, Manuel; Rodríguez García, Raquel; Rodríguez Esteban, María Ángeles; Fariñas, María Carmen; González-Rico, Claudia; Goenaga Sánchez, Miguel Ángel; Ojeda Burgos, Guillermo; Goikoetxea Agirre, Ane Josune; Calderón Parra, Jorge; López Azor, Juan Carlos; García Vázquez, Elisa; Loeches, Belén; Quintana, Eduard; García de la Mària, Cristina; Llopis Pérez, Jaime; Miró Meda, José M.; the GAMES Investigators (Publication date: 2026-02-24)

    Background Coagulase-negative staphylococci (CoNS) are an increasingly common cause of infective endocarditis (IE) and lack recent data from large studies. Objectives Our aim was to describe the epidemiology, clinical ...

    Characteristics and outcome of acute heart failure in infective endocarditis: focus on cardiogenic shock. 

    Pericàs, Juan M.; Hernández Meneses, Marta; Muñoz, Patricia; Martínez Sellés, Manuel; Álvarez Uria, Ana; Alarcón, Aristides de; Gutiérrez Carretero, Encarnación; Goenaga Sánchez, Miguel Ángel; Zarauza Navarro, Manuel Jesús; Falces Salvador, Carles; Rodríguez Esteban, María Ángeles; Hidalgo Tenorio, Carmen; Hernández Cabrera, Michele; Miró Meda, José M.; Spanish Collaboration on Endocarditis—Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES) (Publication date: 2026-02-24)

    Background: Studies investigating the impact of cardiogenic shock (CS) on endocarditis are lacking. Methods: Prospectively collected cohort from 35 Spanish centers (2008-2018). Logistic regression analyses were performed ...

    Antidepressant use in older age bipolar disorder (OABD): Results from the GAGE-BD international consortium 

    Rigas, Christina; Lafer, Beny; Mulsant, Benoit; Oluwaniyi, Stephen O.; Patrick, Regan; Radua, Joaquim; Sarna, Kaylee; Schouws, Sigfried; Simhandl, Christian; Soares, Jair C; Sutherland, Ashley N.; Almeida, Osvaldo P.; Tsai, Shang-Ying; Altinbas, Krusat; Vieta i Pascual, Eduard, 1963-; Balanzá-Martínez, Vicent; Villa, Luca M.; Barbosa, Izabela G.; Fiorelli, Nicole; Blumberg, Hilary P.; Villela Nunes, Paula; Briggs, Farren B. S.; Yala, Joy M.; Calkin, Cynthia V.; Sajatovic, Martha; Forester, Brent P.; Rej, Soham; Forlenza, Orestes V.; Hajek, Tomas; Lavin, Paola; Chen, Peijun; Torres Platas, Susana G.; Su, Chien-Lin; Eyler, Lisa T.; Olagunju, Andrew T.; Teixeira, Antonio L.; Dols, Annemiek; Alda, Martin; Haarman, Bartholomeus; Jiménez Martínez, Esther (Publication date: 2026-02-23)

    Background Antidepressants are still commonly prescribed in bipolar disorders, despite ongoing controversy of the potential risk of inducing hypomania/mania. There is limited knowledge about the characteristics of ...

    Lung function predicts mortality in people with serious mental illness: A 6-year follow-up study 

    Jaén Moreno, María José; Laguna Muñoz, David; Del Pozo, Gloria Isabel; Camacho Rodríguez, Cristina; Guler, Ipek; Alcalá, José Ángel; Reyes López, Micaela; Alcántara García, Montserrat; Benítez Jurado, Diego; Ruiz Rull, Cristina; Jiménez Peinado, Ana; Feu, Nuria; Vieta i Pascual, Eduard, 1963-; Balanzá-Martínez, Vicent; Sarramea, Fernando (Publication date: 2026-02-23)

    Background: The population with a serious mental illness (SMI) shows a high risk of premature mortality. Overexposed to multiple health risks throughout life, their main threat is physical illness, which starts earlier and ...

    Olfactory impairment in Parkinson's disease and white matter abnormalities in central olfactory areas: a voxel-based diffusion tensor imaging study 

    Ibarretxe-Bilbao, Naroa; Junqué i Plaja, Carme, 1955-; Martí Domènech, Ma. Josep; Valldeoriola Serra, Francesc; Vendrell i Gómez, Pere; Bargalló Alabart, Núria; Zarei, Mojtaba; Tolosa, Eduardo (Publication date: 2026-02-23)

    Olfactory dysfunction is known to occur before the appearance of the classical motor signs in Parkinson's disease (PD) and diffusion tensor imaging (DTI) studies in PD have reported fractional anisotropy (FA) reductions ...