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IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer: Envíos recientes

Mostrando ítems 61-80 de 3163

    A phase II trial of lenalidomide, dexamethasone and cyclophosphamide for newly diagnosed patients with systemic immunoglobulin light chain amyloidosis 

    Cibeira López, Maria Teresa; Oriol, Albert; Lahuerta, Juan José; Mateos, M. Victoria; De La Rubia, Javier; Hernández, Miguel T.; Granell, Miquel; Fernández de Larrea Rodríguez, Carlos José; San Miguel, Jesús F.; Bladé Creixenti, Joan (Fecha de publicación: 2026-02-02)

    Immunomodulatory drugs have been shown to be of benefit in relapsed/refractory immunoglobulin light-chain (AL) amyloidosis. We designed a prospective, multicentre phase II trial of lenalidomide, dexamethasone and ...

    Competing signaling pathways controls electrotaxis 

    Kulkarni, Shardool; Tebar Ramon, Francesc; Rentero Alfonso, Carles; Zhao, Min; Sáez, Pablo (Fecha de publicación: 2026-02-02)

    Understanding how cells follow exogenous cues is a key question for biology, medicine, and bioengineering. Growing evidence shows that electric fields represent a precise and programmable method to control cell migration. ...

    Hippocampal abnormalities and age in chronic schizophrenia: morphometric study across the adult lifespan 

    Pujol, Núria; Penadés Rubio, Rafael; Junqué i Plaja, Carme, 1955-; Dinov, Ivo; Fu, Cynthia H. Y.; Catalán Campos, Rosa; Ibarretxe Bilbao, Naroa; Bargalló Alabart, Núria; Bernardo Arroyo, Miquel; Toga, Arthur; Howard, Robert J.; Costafreda, Sergi G. (Fecha de publicación: 2026-01-30)

    Background: Hippocampal abnormalities have been demonstrated in schizophrenia. It is unclear whether these abnormalities worsen with age, and whether they affect cognition and function. Aims: To determine whether hippocampal ...

    Sharing brain imaging data in the Open Science era: how and why?  

    Giehl, Kathrin; Mutsaerts, Henk-Jan; Aarts, Kristien; Barkhof, Frederik; Caspers. Svenja; Chetelat, Gaël; Colin, Marie-Elisabeth; Düzel, Emrah; Frisoni, Giovanni B.; Ikram, M. Arfan; Jovicich, Jorge; Morbelli, Silvia; Oertel, Wolfgang; Paret, Christian; Perani, Daniela; Ritter, Petra; Segura i Fàbregas, Bàrbara; Wisse, Laura E.M.; De Witte, Elke; Cappa, Stefano F.; van Eimeren, Thilo (Fecha de publicación: 2026-01-29)

    The sharing of human neuroimaging data has great potential to accelerate the development of imaging biomarkers in neurological and psychiatric disorders; however, major obstacles remain in terms of how and why to share ...

    Psychoeducation in bipolar disorder with a SIMPLe smartphone application: Feasibility, acceptability and satisfaction 

    Hidalgo Mazzei, Diego; Mateu, Ainoa; Reinares, María; Murru, Andrea; del Mar Bonnín Roig, Caterina; Varo, Cristina; Valentí Ribas, Marc; Undurraga, Juan; Strejilevich, Sergio; Sánchez Moreno, José; Vieta i Pascual, Eduard, 1963-; Colom, Francesc (Fecha de publicación: 2026-01-29)

    Background: During the last fifteen years, the possibility of delivering psychoeducation programs through Internet-based platforms have been explored. Studies evaluating those programs have shown good to acceptable retention ...

    Treatment of neurocognitive symptoms in unipolar depression: A systematic review and future perspectives 

    Salagre Muñoz, Estela; Solé Cabezuelo, Brisa; Tomioka, Yoko; Fernandes, Brisa; Hidalgo Mazzei, Diego; Garriga, Marina; Jiménez Martínez, Ester; Sánchez Moreno, José; Vieta i Pascual, Eduard, 1963-; Grande i Fullana, Iria (Fecha de publicación: 2026-01-29)

    Background: Cognitive symptoms in Major Depressive Disorder (MDD) are persistent and commonly entail neurocognitive impairment and a decline in quality of life. This systematic review gathers the current scientific evidence ...

    Functional network centrality in obesity: a resting-state and task fMRI study 

    García-García, Isabel; Jurado, Ma. Ángeles (María Ángeles); Garolera i Freixa, Maite; Marqués Iturria, Idoia; Horstmann, Annette; Segura i Fàbregas, Bàrbara; Pueyo Benito, Roser; Sender-Palacios, Maria José; Vernet-Vernet, Maria; Villringer, Arno; Junqué i Plaja, Carme, 1955-; Margulies, Daniel S.; Neumann, Jane (Fecha de publicación: 2026-01-29)

    Obesity is associated with structural and functional alterations in brain areas that are often functionally distinct and anatomically distant. This suggests that obesity is associated with differences in functional ...

    The 2023 Duke-International Society for Cardiovascular Infectious Diseases Criteria for Infective Endocarditis: Updating the Modified Duke Criteria. 

    Meer, Jan T. M. van der; Vaart, Thomas W. van der; Miró Meda, José M. (José María), 1956-; Querido Fortes, Claudio; Fosbøl, Emil; Hannan, Margaret M.; Hasse, Barbara; Hoen, Bruno; Karchmer, Adolf W.; Mestres Lucio, Carlos-Alberto; Petti, Cathy A,; Pizzi, María Nazarena; Preston, Stephen D.; Fowler, Vance G.; Durack, David T.; Selton Suty, Christine; Athan, Eugene; Bayer, Arnold S.; Chamis, Anna Lisa; Dahl, Anders; DiBernardo, Louis; Durante Mangoni, E.; Duval, Xavier; Roque, Albert; Vandenesch, Francois (Fecha de publicación: 2026-01-28)

    The microbiology, epidemiology, diagnostics, and treatment of infective endocarditis (IE) have changed significantly since the Duke Criteria were published in 1994 and modified in 2000. The International Society for ...

    Principal component analysis as an efficient method for capturing multivariate brain signatures of complex disorders—ENIGMA study in people with bipolar disorders and obesity 

    McWhinney, Sean R; Hlinka, Jaroslav; Bakstein, Eduard; Dietze, Lorielle M F; Corkum, Emily L V; Abé, Christoph; Alda, Martin; Alexander, Nina; Benedetti, Francesco; Berk, Michael; Bøen, Erlend; Bonnekoh, Linda M; Boye, Birgitte; Brosch, Katharina; Canales-Rodríguez, Erick J.; Cannon, Dara M; Dannlowski, Udo; Demro, Caroline; Diaz-Zuluaga, Ana; Elvsåshagen, Torbjørn; Eyler, Lisa T.; Fortea, Lydia; Fullerton, Janice M; Goltermann, J.; Gotlib, Ian H; Grotegerd, Dominik; Haarman, Bartholomeus; Hahn, Tim; Howells, Fleur M; Jamalabadi, Hamidreza; Jansen, Andreas; Kircher, Tilo; Klahn, Anna Luisa; Kuplicki, Rayus; Lahud, Elijah; Landén, Mikael; Leehr, Elisabeth J; Lopez-Jaramillo, Carlos; Mackey, Scott; Malt, Ulrik; Martyn, Fiona; Mazza, Elena; McDonald, Colm; McPhilemy, Genevieve; Meier, Sandra; Meinert, Susanne; Melloni, Elisa; Mitchell, Philip B; Nabulsi, Leila; Nenadić, Igor; Nitsch, Robert; Opel, Nils; Ophoff, Roel A.; Ortuño, María; Overs, Bronwyn J; Pineda-Zapata, Julian; Pomarol-Clotet, Edith; Radua, Joaquim; Repple, Jonathan; Roberts, Gloria; Rodriguez-Cano, Elena; Sacchet, Matthew D; Salvador, Raymond; Savitz, Jonathan; Scheffler, Freda; Schofield, Peter R; Schürmeyer, Navid; Shen, Chen; Sim, Kang; Sponheim, Scott R; Stein, Dan J., 1962-; Stein, Frederike; Straube, Benjamin; Suo, Chao; Temmingh, Henk; Teutenberg, Lea; Thomas-Odenthal, Florian; Thomopoulos, Sophia I.; Urosevic, Snezana; Usemann, Paula; van Haren, Neeltje E M; Vargas, Cristian; Vieta i Pascual, Eduard, 1963-; Vilajosana, Enric; Vreeker, Annabel; Winter, Nils R; Yatham, Lakshmi N; Thompson, Paul M.; Andreassen, Ole A.; Ching, Christopher R K; Hajek, Tomas (Fecha de publicación: 2026-01-27)

    Multivariate techniques better fit the anatomy of complex neuropsychiatric disorders which are characterized not by alterations in a single region, but rather by variations across distributed brain networks. Here, we used ...

    Endoscopic transorbital avenue to the skull base: Four-step conceptual analysis of the anatomic journey. 

    Guizzardi, Giulia; Di Somma, Alberto; de Notaris, Matteo; Corrivetti, Francesco; Sánchez, Juan Carlos; Alobid, Isam; Ferres, Abel; Roldán Ramos, Pedro; Reyes, Luis; Enseñat Nora, Joaquim; Prats Galino, Alberto (Fecha de publicación: 2026-01-27)

    Background: In the last decades, skull base surgery had passed through an impressive evolution. The role of neuroanatomic research has been uppermost, and it has played a central role in the development of novel techniques ...

    Immune microenvironment and intrinsic subtyping in hormone receptor-positive/HER2-negative breast cancer 

    Ficarra, Guido; Prat Aparicio, Aleix; Conte, Pierfranco; Guarneri, Valentina; Griguolo, Gaia; Dieci, Maria Vittoria; Paré, Laia; Miglietta, Federica; Generali, Daniele; Frassoldati, Antonio; Cavanna, Luigi; Bisagni, Giancarlo; Piacentini, Federico; Tagliafico, Enrico; Cagossi, Katia (Fecha de publicación: 2026-01-26)

    Little is known regarding the interaction between immune microenvironment and tumorbiology in hormone receptor (HR)+/HER2− breast cancer (BC). We here assess pretreatmentgene-expression data from 66 HR+/HER2− early BCs ...

    Immune-related adverse events of checkpoint inhibitors 

    Ramos Casals, Manuel; Brahmer, Julie R.; Callahan, Margaret K.; Flores-Chavez, Alejandro; Keegan, Niamh; Khamashta, Munther A; Lambotte, Olivier; Marlette, Xavier; Prat Aparicio, Aleix; Suarez Almazor, Maria E. (Fecha de publicación: 2026-01-26)

    Cancer immunotherapies have changed the landscape of cancer treatment during the past few decades. Among them, immune checkpoint inhibitors, which target PD-1, PD-L1 and CTLA-4, are increasingly used for certain cancers; ...

    Tumor biomarkers and efficacy in patients treated with trastuzumab emtansine + pertuzumab versus standard of care in HER2-positive early breast cancer: an open-label, phase III study (KRISTINE) 

    de Haas, Sanne L; Slamon, Dennis J; Martin, Miguel; Press, Michael F; Lewis, Gail D; Lambertini, Chiara; Prat Aparicio, Aleix; Lopez-Valverde, Vanesa; Boulet, Thomas; Hurvitz, Sara A (Fecha de publicación: 2026-01-23)

    Background: KRISTINE is an open-label, phase III study of trastuzumab emtansine + pertuzumab (T-DM1 + P) versus docetaxel + carboplatin + trastuzumab + pertuzumab (TCH + P) in patients with HER2-positive, stage II-III ...

    Regional differences in mortality risk and in attenuating or aggravating factors in schizophrenia: A systematic review and meta-analysis 

    Solmi, Marco; Croatto, Giovanni; Fornaro, Michele; Schneider, Lynne Kolton; Rohani-Montez, S. Christy; Fairley, Leanne; Smith, Nathalie; Bitter, István; Gorwood, Philip; Taipale, Heidi; Tiihonen, Jari; Cortese, Samuele; Dragioti, Elena; Rietz, Eva Du; Nielsen, Rene Ernst; Firth, Joseph; Fusar-Poli, Paolo; Hartman, Catharina; Holt, Richard I.G.; Høye, Anne; Koyanagi, Ai; Larsson, Henrik; Lehto, Kelli; Lindgren, Peter; Manchia, Mirko; Nordentoft, Merete; Skonieczna-Żydecka, Karolina; Stubbs, Brendon; Vancampfort, Davy; Boyer, Laurent; De Prisco, Michele; Vieta i Pascual, Eduard, 1963-; Correll, Christoph U.; ECNP Physical And meNtal Health Thematic Working Group (PAN-Health) (Fecha de publicación: 2026-01-23)

    People with schizophrenia die prematurely, yet regional differences are unclear. PRISMA 2020-compliant systematic review/random-effects meta-analysis of cohort studies assessing mortality relative risk (RR) versus any ...

    Unravelling the Link Between Body Mass Index and Cognitive Performance in Individuals With Bipolar Disorder and Exploration of PRS Moderation Effect: Findings From the PsyCourse Study 

    Solé Cabezuelo, Brisa; Montejo Egido, Laura; Budde, Monika; Valentí Ribas, Marc; Borràs, Roger; Martín Parra, Sara; Ruiz Muñoz, Andrea; Martínez-Arán, Anabel, 1971-; Adorjan, Kristina; Heilbronner, Maria; Navarro Flores, Alba; Kohshour, Mojtaba Oraki; Reich-Erkelenz, Daniela; Schulte, Eva C.; Senner, Fanny; Anghelescu, I.G.; Arolt, Volker; Baune, Bernhard T.; Dannlowski, Udo; Dietrich, Detlef E.; Fallgatter, Andreas J.; Figge, Christian; Juckel, Georg; Konrad, Carsten; Reimer, Jens; Reininghaus, Eva Z.; Schmauß, Max; Spitzer, Carsten; Wiltfang, Jens; Zimmermann, Jorg; Falkai, Peter; Vieta i Pascual, Eduard, 1963-; Schulze, Thomas G.; Torrent Font, Carla; Heilbronner, Urs; Papiol, Sergi (Fecha de publicación: 2026-01-22)

    Introduction: Bipolar disorder (BD) is a severe mental disorder characterized by extreme mood swings, often accompanied by metabolic comorbidities, such as cardiovascular disease, which increase mortality and reduce quality ...

    Prognostic value of baseline FDG PET/CT in HER2-positive metastatic breast cancer treated with first-line trastuzumab, pertuzumab, and docetaxel 

    Kubeczko, Marcin; d'Amico, Andrea; Chrabanski, Olgierd; Handkiewicz-Junak, Daria; Polakiewicz-Gilowsk, Anna; Swiderska, Katarzyna; Mianowska-Malec, Marta; Lesniak, Aleksandra; Lanoszka, Barbarba; Lisovska, Natalya; Borys, Damian; Pycinski, Bartlomiej; Ewa Chmielik; Slawomir Blamek; Prat Aparicio, Aleix; Michal Jarzab (Fecha de publicación: 2026-01-22)

    Trastuzumab, pertuzumab, and docetaxel (THP) have represented the standard first-line treatment for HER2-positive metastatic breast cancer (MBC) for over a decade, following the pivotal CLEOPATRA trial. However, interim ...

    Pulmonary vascular reactivity in growth restricted fetuses using computational modelling and machine learning analysis of fetal Doppler waveforms 

    Vellvé, Kilian; Garcia Canadilla, Patricia; Nogueira, Mariana; Youssef, Lina; Arranz Betegón, Angela; Nakaki, Ayako; Boada, David; Blanco Vich, Isabel; Faner, Rosa; Figueras Retuerta, Francesc; Agustí García-Navarro, Àlvar; Gratacós Solsona, Eduard; Crovetto, Francesca; Bijnens, Bart; Crispi Brillas, Fàtima (Fecha de publicación: 2026-01-16)

    The aim of this study was to investigate the pulmonary vasculature in baseline conditions and after maternal hyperoxygenation in growth restricted fetuses (FGR). A prospective cohort study of singleton pregnancies including ...

    Low-cost, open-source device for applying controlled olfactory stimuli during functional magnetic resonance imaging (fMRI) of the brain 

    Salama, Raffaella; Rodríguez Lázaro, Miguel A.; Castelo-Branco Flores, Camil; Herrero Vidaurre, Iñigo; Ribera Torres, Laura; Muñoz-Moreno, Emma; Farré Ventura, Ramon; Otero Hermo, Jorge (Fecha de publicación: 2026-01-16)

     Using functional magnetic resonance imaging (fMRI) to assess brain activity in response to olfactory stimuli is of great biomedical and clinical interest. However, application of controlled sequences of olfactory stimuli ...

    Evaluating maintenance electroconvulsive therapy in Bipolar Disorders: 3-year mirror-image study 

    Madero Gómez, Santiago; Anmella, Gerard; Sagué Vilavella, Maria; Pons-Cabrera, Maria Teresa; Giménez Palomo, Anna; Murru, Andrea; Gómez-Ramiro, Marta; Gil Badenes, Joaquín; Ríos, José; Bioque Alcázar, Miquel; Vieta i Pascual, Eduard, 1963-; Benabarre, Antonio (Fecha de publicación: 2026-01-15)

    Backgorund: Maintenance electroconvulsive therapy (mECT) is underused in the treatment of bipolar disorder (BD). We aimed to study the real-life effectiveness of mECT in BD. Methods: Naturalistic 3-year mirror-image study ...

    Identifying neurocognitive heterogeneity in Older Adults with Bipolar Disorder: a cluster analysis 

    Montejo Egido, Laura; Jiménez Martínez, Ester; Solé Cabezuelo, Brisa; Murru, Andrea; Arbelo, Néstor; Benabarre, Antonio; Valentí Ribas, Marc; Clougher, Derek; Rodríguez, M.A.; Borràs, Roger; Martínez-Arán, Anabel, 1971-; Vieta i Pascual, Eduard, 1963-; Bonnín Roig, Caterina del Mar; Torrent Font, Carla (Fecha de publicación: 2026-01-15)

    Background: Cognitive profiles of BD patients show a demonstrated heterogeneity among young and middle-aged patients, but this issue has not yet deeply explored in Older Adults with bipolar disorder (OABD). The aim of the ...