1. Home
  2. Universitat de Barcelona
  3. IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer
  4. Recent submissions

IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer: Recent submissions

Now showing items 301-320 of 3164

    Premature Ovarian Insufficiency: The Spanish Menopause Society (AEEM) and the European Society of Gynecology (ESG) position statement  

    Castelo-Branco Flores, Camil; Guinot Gasull, Misericordia; Baquedano Mainar, Laura; Cancelo Hidalgo, María J.; Cano, Antonio; Gil Arribas, Elisa; Lobo Martínez, Sonia; Llaneza Suárez, Cristina; Llaneza Coto, Plácido; Mendoza Ladrón de Guevara, Nicolás; Perelson del Pozo, Irene; Quereda, Francisco; Roca Comella, Beatriz; Romagosa, Carla; Romero Duarte, Pablo; Chabbert-Buffet, Nathalie; Serfaty, David; Genazzani Andrea (Publication date: 2026-01-14)

    Premature ovarian insufficiency (POI) is an uncommon condition affecting 1–2% of women younger than 40, 1 in 1,000 in their thirties and 1 in 10,000 under 20 years of age. The multiple etiologies of this clinical condition ...

    Multiplex Antibody Analysis of IgM, IgA and IgG to SARS-CoV-2 in Saliva and Serum From Infected Children and Their Close Contacts 

    Dobaño, Carlota, 1969-; Alonso, Selena; Vidal, Marta; Jiménez, Alfons; Rubio, Rocío; Santano, Rebeca; Barrios, Diana; Pons Tomàs, Gemma; Melé Casas, Maria; Hernández García, María; Girona Alarcón, Mònica; Puyol, Laura; Baro, Bàrbara; Millat Martínez, Pere; Ajanovic, Sara; Balanza Lombardia, Núria; Arias, Sara; Rodrigo Melero, Natalia; Carolis, Carlo; García Miquel, Aleix; Bonet Carné, Elisenda; Claverol, Joana; Cubells, Marta; Fortuny Guasch, Claudia; Fumadó, Victoria; Codina, Anna; Bassat Orellana, Quique; Muñoz Almagro, Carmen; Fernández de Sevilla Estrach, Mariona; Gratacós Solsona, Eduard; Izquierdo Lázaro, Luis; García García, Juan José; Aguilar, Ruth; Jordán García, Iolanda; Moncunill Piñas, Gemma (Publication date: 2022-06-20)

    COVID-19 affects children to a lesser extent than adults but they can still get infected and transmit SARS-CoV-2 to their contacts. Field deployable non-invasive sensitive diagnostic techniques are needed to evaluate the ...

    Chronic Obstructive Pulmonary Disease and Lung Cancer: A Review for Clinicians 

    Criner, Gerard J.; Agustí García-Navarro, Àlvar; Borghaei, Hossein; Friedberg, Joseph; Martinez, Fernando J.; Miyamoto, Curtis; Vogelmeier, Claus F.; Celli, Bartolome R. (Publication date: 2023-05-29)

    Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are common global causes of morbidity and mortality. Because both diseases share several predisposing risks, the two diseases may occur concurrently in ...

    Clinically relevant effect of rupatadine 20 mg and 10 mg in seasonal allergic rhinitis: a pooled responder analysis 

    Mullol i Miret, Joaquim; Izquierdo, Iñaki; Okubo, Kimihiro; Canonica, Giorgio Walter; Bousquet, Jean; Valero, Antonio (Publication date: 2020-03-03)

    Background: Diferent clinical trials showed the superior efcacy of rupatadine compared to placebo at improving seasonal allergic rhinitis (SAR) symptoms, but no study has assessed if the response promoted is clinically ...

    Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients. 

    García-López, Mireia; Lens García, Sabela; Pallett, Laura J.; Testoni, Barbara; Rodríguez Tajes, Sergio; Mariño Méndez, Zoe; Bartrés, Concepció; García Pras, Ester; Leonel, Thais; Perpiñán, Elena; Lozano, Juan José; Rodríguez-Frías, Francisco; Koutsoudakis, George; Zoulim, Fabien; Maini, Mala K; Forns, Xavier; Pérez del Pulgar Gallart, Sofía (Publication date: 2024-09-03)

    Background & aims: Factors associated with a successful outcome upon nucleos(t)ide analogue (NA) treatment withdrawal in HBeAg-negative chronic hepatitis B (CHB) patients have yet to be clarified. The objective of this ...

    Performance analysis of a STEMI network: prognostic impact of the type of first medical contact facility 

    de Diego, Oriol; Rueda Sobella, Ferran; Carrillo, Xavier; Oliveras, Teresa; Andrea, Rut; Ouaddi, Nabil El; Serra, Jordi; Labata, Carlos; Ferrer, Marc; Martínez Membrive, María J.; Montero, Santiago; Mauri, Josepa; García Picart, Joan; Rojas, Sergio; Ariza, Albert; Tizon Marcos, Helena; Faiges, Marta; Cárdenas, Mérida; Lidón, Rosa María; Muñoz Camacho, Juan F.; Jiménez Fàbrega, Xavier; Lupón, Josep; Bayes Genis, Antoni; García García, Cosme; Codi Infart Registry Investigators (Publication date: 2024-03-04)

    Prognosis in ST-elevation myocardial infarction (STEMI) is determined by delay in primary percutaneous coronary intervention (PPCI). The impact of first medical contact (FMC) facility type on reperfusion delays and mortality ...

    Cognitive dysfunction in Huntington¿s disease: Humans, mouse models and molecular mechanisms 

    Giralt Torroella, Albert; Saavedra, Ana; Alberch i Vié, Jordi, 1959-; Pérez Navarro, Esther (Publication date: 2022-02-17)

    Huntington's disease (HD) is an autosomal dominant progressive neurodegenerative disorder due to an expanded CAG/polyglutamine repeat in the coding region of the huntingtin (htt) gene that causes the preferential degeneration ...

    The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas 

    Sanchez Tillo, E.; Pedrosa, Leire; Vila, I.; Chen, Yao; Gyorffy, B.; Sánchez Moral, L.; Siles Mena, Laura; Lozano Salvatella, Juan José; Esteve Codina, A.; Darling, Douglas S.; Cuatrecasas Freixas, Miriam; Castells Garangou, Antoni; Maurel Santasusana, Joan; Postigo, Antonio (Publication date: 2024-03-13)

    Despite being in the same pathway, mutations of KRAS and BRAF in colorectal carcinomas (CRCs) determine distinct progression courses. ZEB1 induces an epithelial-to-mesenchymal transition (EMT) and is associated with worse ...

    Development and external validation of predictive models for prevalent and recurrent atrial fibrillation: a protocol for the analysis of the CATCH ME combined dataset 

    Chua, Winnie; Easter, Christina L.; Guasch i Casany, Eduard; Sitch, Alice; Casadei, Barabara; Crijns, Harry J.G.M.; Haase, Doreen; Hatem Stéphane; Kääb, Stefan; Mont Girbau, Lluís; Schotten, Ulrich; Sinner, Moritz F.; Hemming, Karla; Deeks, Jonathan J.; Kirchhof, Paulus; Fabritz, Larissa (Publication date: 2020-05-29)

    Background: Atrial fibrillation (AF) is caused by different mechanisms but current treatment strategies do not target these mechanisms. Stratified therapy based on mechanistic drivers and biomarkers of AF have the potential ...

    Characterization of digestive disorders of patients with chronic Chagas disease in Cochabamba, Bolivia 

    Pinto, Jimy-Jose; Pinazo, Maria-Jesus; Saravia, Jaime; Gainsborg, Ingrid; Magne, Helmut-Ramon; Cuatrecasas Freixas, Miriam; Cortés Serra, Núria; Lozano Beltran, Daniel-Franz; Gascón i Brustenga, Joaquim; Torrico, Faustino (Publication date: 2019-06-18)

    Background: Chagas disease (CD) is endemic in Latin America and particularly common in Bolivia, but there is little information on the characteristics of chronic digestive involvement. Objectives: To determine the ...

    SiNoPsis: single nucleotide polymorphisms selection and promoter profiling 

    Boloc, Daniel; Rodríguez Ferret, Natalia; Gassó Astorga, Patricia; Abril Ferrando, Josep Francesc, 1970-; Bernardo Arroyo, Miquel; Lafuente, Amàlia, 1952-2022; Mas Herrero, Sergi (Publication date: 2023-03-21)

    Motivation: The selection of a single nucleotide polymorphism (SNP) using bibliographic methods can be a very time-consuming task. Moreover, a SNP selected in this way may not be easily visualized in its genomic context ...

    Susac Syndrome: Description of a Single-Centre Case Series 

    Beça, Sara; Elera Fitzcarrald, Claudia; Saiz, Albert; Llufriu Duran, Sara; Cid, María C.; Sánchez Dalmau, Bernardo; Adán Civera, Alfredo; Espinosa Garriga, Gerard (Publication date: 2023-05-12)

    This study describes the clinical characteristics, diagnostic results, treatment regimens, and clinical course of a cohort of patients with Susac syndrome (SS). It is a retrospective observational study of all patients ...

    The influence of CYP enzymes and ABCB1 on treatment outcomes in schizophrenia: association of CYP1A2 activity with adverse effects 

    Cendrós, Marc; Arranz, María Jesús; Torra, Mercè; Penadés Rubio, Rafael; Gonzalez-Rodriguez A; Brunet i Serra, Mercè; Pérez Blanco, Josefina; Ibáñez Lladó, Laura; Serra, Àlex; Catalán, Rosa (Publication date: 2021-02-15)

    Aim: Genetic variants on metabolic and transport enzymes are good candidates to explain inter-individual differences in response to antipsychotics. The aim of this study is to evaluate and compare the influence of the ...

    QT interval and short-term outcome in acute heart failure 

    Miró i Andreu, Òscar; Aguiló, Oriol; Trullàs, Joan Carles; Gil Espinosa, Victor; Espinosa, Begoña; Jacob, Javier; Herrero Puente, Pablo; Tost, Josep; López-Grima, María Luisa; Comas, Pere; Bibiano, Carlos; Llauger, Lluís; Martín Mojarro, Enrique; López Díez, María Pilar; Nuñez, Julio; Rafique, Zubaid; Keene, Kelly R.; Peacock, Frank; Lopez-Ayala, Pedro; Mueller, Christian; Montero Pérez-Barquero, Manuel; Mont Girbau, Lluís; Llorens Soriano, Pere; ICA-SEMES research investigators (Publication date: 2025-04-30)

    Objective: To investigate the association of corrected QT (QTc) interval duration and short-term outcomes in patients with acute heart failure (AHF). Methods: We analyzed AHF patients enrolled in 11 Spanish emergency ...

    Dietary diversity and Depression: Cross-sectional and longitudinal analyses in Spanish adult population with Metabolic Syndrome. Findings from PREDIMED-PLUS Trial. 

    Cano Ibáñez, Naomi; Serra Majem, Lluís; Martín-Peláez, Sandra; Martínez-González, Miguel Ángel, 1957-; Salas Salvadó, Jordi; Corella Piquer, Dolores; Lassale, Camille; Martínez Hernández, José Alfredo; Alonso Gómez, Ángel M.; Wärnberg, Julia; Vioque, Jesús; Romaguera, Dora; López-Miranda J; Estruch Riba, Ramon; Gómez Pérez, Ana María; Lapetra, José; Fernández Aranda, Fernando; Bueno-Cavanillas, Aurora; Tur, Josep Antoni; Cubelos Fernández, Naiara; Pintó Sala, Xavier; Gaforio, José J.; Matía Martín, Pilar; Vidal Cortada, Josep; Calderón, Cristina; Daimiel, Lidia; Ros Rahola, Emilio; Gea, Alfredo; Babio, Nancy; Gimenez Alba, Ignacio Manuel; Zomeño Fajardo, María Dolores; Abete, Itziar; Tojal Sierra, Lucas; Romero Galisteo, Rita Pilar; García de la Hera, Manuela; Martín Padillo, Marian; García Rios, Antonio; Casas Rodríguez, Rosa M.; Fernández García, José C.; Santos Lozano, José Manuel; Toledo Atucha, Estefanía; Becerra Tomás, Nerea; Sorlí, José V.; Schröder, Helmut, 1958-; Zulet, M. Angeles; Sorto Sanchez, Carolina; Diez Espino, Javier; Gómez Martínez, Carlos; Fitó Colomer, Montserrat; Sánchez-Villegas, Almudena (Publication date: 2024-04-17)

    Objective: To examine the cross-sectional and longitudinal (2-year follow-up) associations between Dietary Diversity (DD) and depressive symptoms. Design: An energy-adjusted Dietary Diversity Score (DDS) was assessed using ...

    The LEAD (Lung, Heart, Social, Body) Study: Objectives, Methodology, and External Validity of the Population-Based Cohort Study 

    Breyer-Kohansal, Robab; Hartl, Sylvia; Burghuber, Otto Chris; Urban, Matthias; Schrott, Andrea; Agustí García-Navarro, Àlvar; Sigsgaard, Torben; Vogelmeier, Claus F.; Wouters, Emiel; Studnicka, Michael; Breyer, Marie Kathrin (Publication date: 2020-04-23)

    BACKGROUND: The Lung, hEart, sociAl, boDy (LEAD) Study (ClinicalTrials.gov; NCT01727518; http://clinicaltrials.gov) is a longitudinal, observational, population-based Austrian cohort that aims to investigate the relationship ...

    Circulating inflammatory cells in patients with metastatic breast cancer: Implications for treatment 

    Gianni, Caterina; Palleschi, Michela; Schepisi, Giuseppe; Casadei, Chiara; Bleve, Sara; Merloni, Filippo; Sirico, Marianna; Sarti, Samanta; Cecconetto, Lorenzo; Di Menna, Giandomenico; Schettini, Francesco; De Giorgi, Ugo (Publication date: 2023-03-01)

    Adaptive and innate immune cells play a crucial role as regulators of cancer development. Inflammatory cells in blood flow seem to be involved in pro-tumor activities and contribute to breast cancer progression. Circulating ...

    Reconstituted human upper airway epithelium as 3-d in vitro model for nasal polyposis. 

    Callejas, Francisco de Borja; Martínez Antón, Ma. Asunción; Alobid, Isam; Fuentes Prado, Mireya; Cortijo, Julio; Picado Vallés, César; Roca i Ferrer, Jordi; Mullol i Miret, Joaquim (Publication date: 2018-05-07)

    BACKGROUND: Primary human airway epithelial cells cultured in an air-liquid interface (ALI) develop a well-differentiated epithelium. However, neither characterization of mucociliar differentiation overtime nor the ...

    Cost-accuracy and patient experience assessment of blood pressure monitoring methods to diagnose hypertension: A comparative effectiveness study 

    González de Paz, Luis; Kostov, Bechim; Freixa, Xavier; Herranz, Carmen; Lagarda, Elena; Ortega, María; Pérez, Elisa; Porcar, Sílvia; Sánchez, Eva; Serrato, Montserrat; Vidiella, Íngrid; Sisó Almirall, Antoni (Publication date: 2024-03-25)

    Studies of the diagnosis of hypertension have emphasized long-term cost-effectiveness analysis, but the patient experience and costs of blood pressure monitoring methods at the diagnosis stage remain unclear. We studied ...

    Exploring risk and resilient profiles for functional impairment and baseline predictors in a 2-year follow-up first-episode psychosis cohort using latent class growth analysis 

    Salagre Muñoz, Estela; Grande i Fullana, Iria; Solé Cabezuelo, Brisa; Mezquida Mateos, Gisela; Cuesta, Manuel J.; Díaz Caneja, Covadonga M.; Amoretti Guadall, Silvia; Lobo, Antonio; González-Pinto, Ana; Moreno, Carmen (Moreno Koch); Pina Camacho, Laura; Corripio, Iluminada; Baeza, Inmaculada, 1970-; Bergé, Daniel; Verdolini, Norma; Carvalho, André F.; Vieta i Pascual, Eduard, 1963-; Bernardo Arroyo, Miquel; PEPs Group (Publication date: 2021-02-18)

    Being able to predict functional outcomes after First-Episode Psychosis (FEP) is a major goal in psychiatry. Thus, we aimed to identify trajectories of psychosocial functioning in a FEP cohort followed-up for 2 years in ...