Ara mostrant els elements 141-160 de 3164

    Effects of APOE-ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease 

    Cacciaglia, Raffaele; Molinuevo, José Luis; Falcón, Carles; Brugulat Serrat, Anna; Sánchez Benavides, Gonzalo; Gramunt Fombuena, Nina; Esteller, Manel; Moran, Sebastian; Minguillón, Carolina; Fauria, Karine; Gispert, Juan Domingo (Data de publicació: 2021-04-08)

    INTRODUCTION: Apolipoprotein E (APOE)-ε4 is the major genetic risk factor for Alzheimer's disease. However, the dose-dependent impact of this allele on brain morphology of healthy individuals remains unclear. METHODS: We ...

    Lifetime psychotic symptoms, subthreshold depression and cognitive impairment as barriers to functional recovery in patients with bipolar disorder 

    Bonnín Roig, Caterina del Mar; Jiménez Martínez, Ester; Solé Cabezuelo, Brisa; Torrent Font, Carla; Radua, Joaquim; Reinares, María; Grande i Fullana, Iria; Ruíz, Victoria; Sánchez-Moreno, José; Martínez-Arán, Anabel, 1971-; Vieta i Pascual, Eduard, 1963- (Data de publicació: 2020-04-21)

    Background: bipolar disorder (BD) is a chronic disease that often leads to functional impairment. The objective of this study is to elucidate which variables are associated with better functional outcomes in a sample of ...

    Micro-needle implantable electrochemical oxygen sensor: ex-vivo and in-vivo studies 

    Rivas, Lourdes; Dulay, Samuel; Miserere, Sandrine; Pla, Laura; Berdún Marin, Sergio; Parra, Johanna; Eixarch Roca, Elisenda; Gratacós Solsona, Eduard; Illa Armengol, Míriam; Mir Llorente, Mònica; Samitier i Martí, Josep (Data de publicació: 2023-07-17)

    Oxygen is vital for energy metabolism in mammals and the variability of the concentration is considered a clinical alert for a wide range of metabolic malfunctions in medicine. In this article, we describe the development ...

    Protocol for the management of psychiatric patients with psychomotor agitation 

    Vieta i Pascual, Eduard, 1963-; Garriga, Marina; Cardete Morales, Laura; Bernardo Arroyo, Miquel; Lombraña Mencia, Maria; Blanch Andreu, Jordi; Catalán, Rosa; Vázquez, Mireia; Soler, Victòria; Ortuño, Noélia; Martínez-Arán, Anabel, 1971- (Data de publicació: 2018-05-02)

    Background: Psychomotor agitation (PMA) is a state of motor restlessness and mental tension that requires prompt recognition, appropriate assessment and management to minimize anxiety for the patient and reduce the risk ...

    Borderline, Where Are You? A Psychometric Approach to the Personality Domains in the International Classification of Diseases, 11th Revision (ICD-11) 

    Gutiérrez, Fernando; Aluja Fabregat, Anton; Ruiz Rodríguez, José; Peri, Josep M.; Gárriz, Miguel; García, Luis F.; Sorrel Luján, Miguel Ángel; Sureda Caldentey, Bàrbara; Vall, Gemma; Ferrer Vinardell, Marc; Calvo Piñero, Natàlia (Data de publicació: 2024-01-26)

    The inclusion of the borderline pattern in the International Classification of Diseases, 11th Revision (ICD-11) dimensional classification of personality disorders (PDs) has caused controversy. Unease about leaving out ...

    Mental slowness and executive dysfunctions in patients with metabolic syndrome 

    Segura i Fàbregas, Bàrbara; Jurado, Ma. Ángeles (María Ángeles); Freixenet, Núria; Albuin, Carlota; Muniesa, Jesús; Junqué i Plaja, Carme, 1955- (Data de publicació: 2020-05-20)

    Metabolic Syndrome is a cluster of vascular risk factors which has been related to dementia and cognitive decline. The aim of this study was to describe the neuropsychological profile of metabolic syndrome patients. An ...

    Trastorno por déficit de atención con hiperactividad. Asimetrías cerebrales observadas en resonancia magnética. 

    Pueyo Benito, Roser; Mañeru Zunazarren, Cristina; Vendrell i Gómez, Pere; Mataró Serrat, Maria; Estévez González, Armando; García Sánchez, Carmen; Junqué i Plaja, Carme, 1955- (Data de publicació: 2025-09-26)

    [spa] Introducción Los estudios de neuroimagen estructural y funcional en sujetos con trastorno por déficit de atención con hiperactividad (TDAH) han sugerido una inversión de los patrones de asimetría cerebral y una ...

    Functional brain abnormalities in post COVID-19 condition and their relationship with cognition. 

    Carreras Vidal, Lourdes; Pacheco Jaime, Laura; Ariza González, Mar; Cano, Neus; Garolera i Freixa, Maite; García Vicente, Carla; Roura, Ignacio; Capdevila Lacasa, Clara; Oltra González, Javier; Pardo, Jèssica; Martín Barceló, Cristina; Campabadal Delgado, Anna; Sala Llonch, Roser; Bargalló Alabart, Núria; Barrué, Cristian; Bejar, Javier; Cortés, Claudio Ulises; Junqué i Plaja, Carme, 1955-; NAUTILUS-Project Collaborative Group; Segura i Fàbregas, Bàrbara (Data de publicació: 2025-09-04)

    After COVID-19 infection, some patients develop a post-COVID condition (PCC) that is popularly referred to as long COVID. Among its symptoms is persistent cognitive dysfunction that is potentially linked to altered brain ...

    Postsurgical Cerebral Perfusion Changes in Idiopathic Normal Pressure Hydrocephalus: A Statistical Parametric Mapping Study of SPECT Images 

    Mataró Serrat, Maria; Poca Pastor, María Antonia; Salgado-Pineda, Pilar; Castell Conesa, Joan; Sahuquillo, Juan; Díez Castro, María Jesús; Aguadé Bruix, Santiago; Vendrell i Gómez, Pere; Matarín, Mar; Junqué i Plaja, Carme, 1955- (Data de publicació: 2025-09-29)

    Our goal was to study cerebral blood flow (CBF) changes after surgery in a group of 15 patients with idiopathic normal pressure hydrocephalus (NPH). Methods: We used hexamethylpropyleneamine oxime SPECT and statistical ...

    Influence of Music on Anxiety Induced by Fear of Heights in Virtual Reality 

    Seinfeld, Sofia; Bergstrom, Ilias; Pomés Freixa, Ausiàs; Arroyo Palacios, Jorge; Vico, Francisco; Slater, Mel; Sánchez-Vives, María Victoria (Data de publicació: 2019-01-23)

    Music is a potent mood regulator that can induce relaxation and reduce anxiety in different situations. While several studies demonstrate that certain types of music have a subjective anxiolytic effect, the reported results ...

    Effects of cTBS on the Frequency-Following Response and Other Auditory Evoked Potentials 

    López Caballero, Francisco José; Martín Trias, Pablo; Ribas Prats, Teresa; Gorina-Careta, Natàlia; Bartrés Faz, David; Escera i Micó, Carles (Data de publicació: 2021-04-28)

    The frequency-following response (FFR) is an auditory evoked potential (AEP) that follows the periodic characteristics of a sound. Despite being a widely studied biosignal in auditory neuroscience, the neural underpinnings ...

    Improved classification of leukemic B-cell lymphoproliferative disorders using a transcriptional and genetic classifier 

    Navarro, Alba; Clot Razquin, Guillem; Martínez Trillos, Alejandra; Pinyol, Magda; Jares Gerboles, Pedro; González Farré, Blanca; Martínez, Daniel; Trim, Nicola; Fernàndez Pascual, Verònica; Villamor i Casas, Neus; Colomer Pujol, Dolors; Costa, Dolors; Salaverria Frigola, Itziar; Martín García, David; Erber, Wendy; López González, Cristina; Jayne, Sandrine; Siebert, Reiner; Dyer, Martin J. S.; Wiestner, Adrian; Wilson, Wyndham H.; Aymerich Gregorio, Marta; López Guillermo, Armando; Sànchez, Àlex (Sànchez Pla); Campo Güerri, Elias; Matutes, Estella; Beà Bobet, Sílvia M. (Data de publicació: 2018-06-11)

    B-cell chronic lymphoproliferative disorders (B-CLPD) encompass a group of hematologic tumors that often present with leukemic involvement.1 Their heterogeneity and the lack of relatively specific diagnostic markers for ...

    Emotional intelligence: A comparison between patients after first episode mania and those suffering from chronic bipolar disorder type i 

    Varo, Cristina; Amoretti Guadall, Silvia; Sparacino, Giulio; Jiménez Martínez, Ester; Solé Cabezuelo, Brisa; Bonnín Roig, Caterina del Mar; Montejo Egido, Laura; Serra Navarro, Maria; Torrent Font, Carla; Salagre Muñoz, Estela; Benabarre, Antonio; Salgado Pineda, Pilar; Montoro Salvatierra, Irene; Sáiz Martínez, Pilar Alejandra; García Portilla, María Paz; Sánchez Gistau, Vanessa; Pomarol-Clotet, Edith; Ramos Quiroga, Josep Antoni; Pacchiarotti, Isabella; García Rizo, Clemente; Undurraga Fourcade, Juan Pablo; Reinares, María; Martínez-Arán, Anabel, 1971-; Vieta i Pascual, Eduard, 1963-; Verdolini, Norma (Data de publicació: 2024-04-23)

    Deficits in emotional intelligence (EI) were detected in patients with Bipolar Disorder (BD), but little is known about whether these deficits are already present in patients after presenting a first episode mania (FEM). ...

    Major Superficial White Matter Abnormalities in Huntington's Disease 

    Phillips, Owen R.; Joshi, Shantanu H.; Squitieri, Ferdinando; Sánchez Castañeda, Cristina; Narr, Katherine; Shattuck, David W.; Caltagirone, Carlo; Sabatini, Umberto; Di Paola, Margherita (Data de publicació: 2019-09-26)

    Background: The late myelinating superficial white matter at the juncture of the cortical gray and white matter comprising the intracortical myelin and short-range association fibers has not received attention in Huntington's ...

    Usefulness of Transcriptional Blood Biomarkers as a Non-invasive Surrogate Marker of Mucosal Healing and Endoscopic Response in Ulcerative Colitis 

    Planell Picola, Núria; Masamunt, Maria Carme; Franco Leal, Raquel; Rodríguez Rubio, Lorena; Esteller Viñal, Miriam; Lozano Salvatella, Juan José; Ramírez Morros, Anna; Setsuko Ayrizono, Maria de Lourdes; Coy, Claudio Saddy Rodrigues; Alfaro, Ignacio; Ordas, Ingrid; Visvanathan, Sudha; Ricart, Elena; Guardiola, Jordi; Panes, Julian; Salas Martínez, Azucena (Data de publicació: 2025-07-03)

    Background and Aims: Ulcerative colitis [UC] is a chronic inflammatory disease of the colon. Colonoscopy remains the gold standard for evaluating disease activity, as clinical symptoms are not sufficiently accurate. The ...

    Reactive oxygen species activate the Drosophila TNF receptor Wengen for damage-induced regeneration 

    Esteban-Collado, José; Fernández Mañas, Mar; Fernández Moreno, Manuel; Maeso, Ignacio; Corominas, Montserrat (Corominas Guiu); Serras Rigalt, Florenci (Data de publicació: 2025-06-27)

    Tumor necrosis factor receptors (TNFRs) control pleiotropic pro-inflammatory functions that range from apoptosis to cell survival. The ability to trigger a particular function will depend on the upstream cues, association ...

    People with type 1 diabetes exhibit lower exercise capacity compared to a control population with similar physical activity levels 

    Murillo, Serafín; Brugnara, Laura; Ríos, Santiago; Ribas, Vicent; Servitja, Joan Marc; Novials, Anna (Data de publicació: 2025-02-20)

    Aims: We aimed to assess physical activity (PA) levels, adherence to PA guidelines, and fitness capacity in individuals with type 1 diabetes (T1D) and control population. Methods: This cross-sectional study included 232 ...

    Hierarchical Structure of Maladaptive Personality Traits 

    Ruiz Rodríguez, José; Gutiérrez, Fernando; Peri, Josep M. (Data de publicació: 2018-09-19)

    Objective: Examine in a clínical samplc the joint hierarchical structurc of personality pathology derived from the 25 primary facets of the Personolity Invenlory (PI D-S; Krueger el al. , 2012) for the fifth edition of ...

    Functional remediation improves bipolar disorder functioning with no effects on brain-derived neurotrophic factor levels 

    Bonnín Roig, Caterina del Mar; Valls Roig, Èlia; Rosa, Adriane R.; Reinares, María; Jiménez Martínez, Ester; Solé Cabezuelo, Brisa; Montejo Egido, Laura; Meseguer, Ana; Pacchiarotti, Isabella; Colom, Francesc, 1971-; Martínez-Arán, Anabel, 1971-; Tomioka, Yoko; Vieta i Pascual, Eduard, 1963-; Torrent Font, Carla (Data de publicació: 2026-02-12)

    The main aim of this study is to evaluate the impact of functional remediation (FR) in serum brain derived neurotrophic factor (BDNF) levels in euthymic adult patients with Bipolar Disorder (BD). A total of 128 participants ...

    Metazoan evolution of glutamate receptors reveals unreported phylogenetic groups and divergent lineage-specific events 

    Ramos Vicente, David; Ji, Jie; Gratacòs i Batlle, Esther; Gou, Gemma; Reig Viader, Rita; Luís, Javier; Burguera, Demian; Navas Pérez, Enrique; García Fernández, Jordi; Fuentes Prior, Pablo; Escriva, Hector; Roher Armentia, Nerea; Soto del Cerro, David; Bayés, Àlex (Data de publicació: 2020-04-24)

    Glutamate receptors are divided in two unrelated families: ionotropic (iGluR), driving synaptic transmission, and metabotropic (mGluR), which modulate synaptic strength. The present classification of GluRs is based on ...