Genètica, Microbiologia i Estadística: Enviaments recents
Ara mostrant els elements 161-180 de 2019
Fifteen years of enzyme replacement therapy for mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome): a case report
Background: Mucopolysaccharidosis VI, or Maroteaux-Lamy disease, is an autosomal recessive disease characterized by defciency of the enzyme arylsulfatase B in the lysosomal catabolism of glycosaminoglycans. Due to reduced ...
The Modular architecture of metallothioneins facilitates domain rearrangements and contributes to their evolvability in metal-accumulating mollusks.
Protein domains are independent structural and functional modules that can rearrange to create new proteins. While the evolution of multidomain proteins through the shuffling of different preexisting domains has been well ...
A conserved role for Syntaxin-1 in pre- and post-commissural midline axonal guidance in fly, chick, and mouse
Axonal growth and guidance rely on correct growth cone responses to guidance cues. Unlike the signaling cascades that link axonal growth to cytoskeletal dynamics, little is known about the crosstalk mechanisms between ...
New sample of drosophilids from the Font Groga site, Barcelona (Spain)
A new sample of drosophilids was obtained from Font Groga (Barcelona) on 9th October 2013. Flies were netted over 12 baits containing fermenting bananas placed along a trail from 4 to 7 pm. The number of flies classified ...
La ciència, joc de nens
Si els nens petits tenen aquesta capacitat innata, cal evitar que la perdin, treballant-la i educant-la
Manipular els gens
l'article Por als gens vaig parlar de la iniciativa per declarar Catalunya lliure de transgènics, i vaig dir que els motius que esgrimeixen els promotors no tenen base científica. Aquests motius es poden resumir en tres ...
Món sintètic
Una de les habilitats més valorades en totes les professions intel·lectuals és la capacitat de síntesi, que ens permet combinar en un tot elements separats i que es fa palesa en la major part d'elements de factura humana. ...
Invasions gelatinoses
Fa anys, durant la meva adolescència, vaig ser un devorador voraç de llibres de ciència-ficció, i no només de ciència-ficció. En un d'aquests llibres, titulat La legió de l'espai (1934), Jack Williamson descriu la invasió ...
Multicentre, randomised, single-blind, parallel group trial to compare the effectiveness of a Holter for Parkinson's symptoms against other clinical monitoring methods: Study protocol
Introduction In recent years, multiple studies have aimed to develop and validate portable technological devices capable of monitoring the motor complications of Parkinson's disease patients (Parkinson's Holter). The ...
Reliable software
In biomedicine, biodiversity and other fields of research, large databases are used. Assuming that a proper statistical procedure has been chosen, a crucial point is the selection of the right software to compute the data. ...
Effectiveness of vancomycin plus cloxacillin compared with vancomycin, cloxacillin and daptomycin single therapies in the treatment of methicillin-resistant and methicillin-susceptible Staphylococcus aureus in a rabbit model of experimental endocarditis
Objectives: To investigate if the addition of cloxacillin to vancomycin enhances the activity of both monotherapies for treating MSSA and MRSA experimental endocarditis (EE) in rabbits. Methods: Vancomycin plus cloxacillin ...
Kernel conditional Embeddings for associating omic data types
Computational methods are needed to combine diverse type of genome-wide data in a meaningful manner. Based on the kernel embedding of conditional probability distributions, a new measure for inferring the degree of association ...
Chromosomal polymorphism of D. subobscura: no differences between wild males and sons of wild females
When analyzing the chromosomal polymorphism of D. subobscura natural populations it is assumed that the information provided by wild males and sons of wild females is equivalent. Thus, using both in the analysis it is ...
Anxiety, mood, and substance use disorders in adult men and women with and without Attention-Deficit/Hyperactivity Disorder: a substantive and methodological overview.
Knowledge on psychiatric comorbidity in adult ADHD is essential for prevention, detection, and treatment of these conditions. This review (1) focuses on large studies (n > 10,000; surveys, claims data, population registries) ...
Sustainable natural bioresources in crop protection: antimicrobial hydroxycoumarins induce membrane depolarization-associated changes in the transcriptome of Ralstonia solanacearum
Background: Ralstonia solanacearum is one of the most devastating pathogens affecting crop production worldwide. The hydroxycoumarins (umbelliferone, esculetin and daphnetin) represent sustainable natural bioresources on ...
Els gens zombis continuen la vida més enllà de la mort
Periòdicament, algunes sèries de televisió, el cinema o la literatura juvenil han posat de moda els zombis. Que ningú es confongui, els zombis són pura ficció i no tenen cap validesa científica. Però un estudi recent indica ...
La coacción desde una perspectiva evolutiva: ¿función biológica o social?
La coacción se define como la fuerza o violencia que se practica sobre alguien para forzar su conducta o voluntad. Es un fenómeno que ha acompañado a la especie humana desde sus albores y sus raíces deben buscarse en el ...
Transcriptomic analysis of Planarians under simulated microgravity or 8g demonstrates that alteration of gravity induces genomic and cellular alterations that could facilitate tumoral transformation
The possibility of humans to live outside of Earth on another planet has attracted the attention of numerous scientists around the world. One of the greatest difficulties is that humans cannot live in an extra-Earth ...
Twitching and swimming motility play a role in Ralstonia solanacearum pathogenicity
Ralstonia solanacearum is a bacterial plant pathogen causing important economic losses worldwide. In addition to the polar flagella responsible for swimming motility, this pathogen produces type IV pili (TFP) that govern ...
El cervell dels adolescents, una època de canvi i transformació.
L'adolescència és una etapa crucial de la vida, un espai de canvi i transformació durant el qual es basteix el que serà la joventut i l'edat adulta. Biològicament, el sentit adaptatiu de l'adolescència és deixar enrere els ...
