Genètica, Microbiologia i Estadística: Enviaments recents
Ara mostrant els elements 101-120 de 2019
Functional Analyses of four CYP1A1 missense mutations present in patients with atypical femoral fractures
Osteoporosis is the most common metabolic bone disorder and nitrogen-containing bisphosphonates (BP) are a first line treatment for it. Yet, atypical femoral fractures (AFF), a rare adverse effect, may appear after prolonged ...
Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar Typhimurium
The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated process. Signaling cascades triggered by different environmental and physiological signals converge to control HilD, ...
Una vacuna per combatre l'addicció a l'heroïna
L' addicció a substàncies estupefaents és un problema de salut individual i social d'abast mundial. Afecta persones de totes les edats i condicions, i s'acostuma a iniciar a l'adolescència. Hi ha substàncies il·legals, com ...
Genome-wide chromatin occupancy reveals a role for ASH2 in transcriptional pausing
While it is widely acknowledged that the ubiquitin-proteasome system plays an important role in transcription, little is known concerning the mechanistic basis, in particular the spatial organization of proteasome-dependent ...
Identification of sapovirus GV.2, astrovirus VA3 and novel anelloviruses in serum from patients with acute hepatitis of unknown aetiology.
Hepatitis is a general term meaning inflammation of the liver, which can be caused by a variety of viruses. However, a substantial number of cases remain with unknown aetiology. We analysed the serum of patients with ...
Selecció d'embrions
Els humans sentim un profund respecte per la mort des de temps immemorials, però massa sovint aquest respecte és més intens que el que sentim per la pròpia vida. Altrament, costa d'entendre que les recents imatges de soldats ...
Per què és important el bosó de Higgs
El professor i investigador de la UB ens explica la rellevància del descobriment realitzat pels científics europeus
What does intrinsic mean in statistical estimation? (with discussion)
In this paper we review different meanings of the word intrinsic in statistical estimation, focusing our attention on the use of this word in the analysis of the properties of an estimator.We review the intrinsic versions ...
Cientisme i humanisme
Aquestes darreres setmanes he llegit diversos articles i he sentit unes quantes persones que parlaven de cientisme. El 26 d'abril, per exemple, Jordi Cabré en va publicar un d'incisiu i sentit on hi feia referència. També ...
Els virus van fer evolucionar el cervell
Un retrovirus va contribuir a incrementar les capacitats cognitives dels éssers humans. Va incidir sobre un gen que també està involucrat en algunes malalties mentals
La Biologia del Desenvolupament
El principal objectiu de la biologia del desenvolupament és entendre com, a partir d'una única cèl·lula ou, indiferenciada es forma el patró d'estructures tridimensionals d'un organisme adult. Aquesta planera definició ...
Two unconventional Metallothioneins in the apple snail Pomacea Bridgesii have lost their metal specificity during adaptation to freshwater habitats
Metallothioneins (MTs) are a diverse group of proteins responsible for the control of metal homeostasis and detoxification. To investigate the impact that environmental conditions might have had on the metal-binding abilities ...
The Critical role of codon composition on the translation efficiency robustness of the Hepatitis A virus capsid
Hepatoviruses show an intriguing deviated codon usage, suggesting an evolutionary signature. Abundant and rare codons in the cellular genome are scarce in the human hepatitis A virus (HAV) genome, while intermediately ...
Expression of deubiquitinating enzyme genes in the developing mammal retina
Purpose: Genes involved in the development and differentiation of the mammalian retina are also associated with inherited retinal dystrophies (IRDs) and age-related macular degeneration. Transcriptional regulation of retinal ...
La música és el llenguatge universal del cervell
La música és un producte de la ment humana. No es coneix cap cultura que no l'hagi desenvolupada i que no la utilitzi. Això ha portat a proposar que la música és el llenguatge universal de la nostra espècie, més enllà de ...
Role of the bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes
Phagocytosis is a key process of the immune system. The human pathogen Klebsiella pneumoniae is a well known example of a pathogen highly resistant to phagocytosis. A wealth of evidence demonstrates that the capsule ...
KatE from the bacterial plant pathogen ralstonia solanacearumis a monofunctional catalase controlled by HrpG that plays a major role in bacterial survival to hydrogen peroxide
Ralstonia solanacearum is the causative agent of bacterial wilt disease on a wide range of plant species. Besides the numerous bacterial activities required for host invasion, those involved in the adaptation to the plant ...
Kernel-PCA data integration with enhanced interpretability
Background Nowadays, combining the different sources of information to improve the biological knowledge available is a challenge in bioinformatics. One of the most powerful methods for integrating heterogeneous data types ...
Quan les ales toquen l'ànima
Hi ha lectures que obren finestres inesperades que deixen entrar un aire gairebé imperceptible, però capaç de transformar-nos. De vegades, aquest corrent arriba des de la introspecció més íntima. D’altres, des del batec ...
How many came home? Evaluating ex‐situ conservation of green turtles in the Cayman Islands
Ex-situ management is an important conservation tool that allows the preservation of biological diversity outside natural habitats while supporting survival in the wild. Captive breeding followed by reintroduction is a ...
