Fonaments Clínics: Recent submissions
Now showing items 121-140 of 627
Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma
BACKGROUND Diffuse large B-cell lymphomas (DLBCLs) are phenotypically and genetically heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B-cell-like [ABC], germinal-center B-cell-like ...
Comparison of two-drug combinations, amikacin/tigecycline/imipenem and amikacin/tigecycline/clarithromycin against Mycobacteroides abscessus subsp. abscessus using the in vitro time-kill assay
Nontuberculous mycobacteria include 198 mycobacterial species. Among these, Mycobacteroides abscessus is a rapidly growing mycobacteria that causes lung and skin infections. M. abscessus lung infections are difficult to ...
Effect of maternal clinical chorioamnionitis on neonatal morbidity in very-low birthweight infants: a case control study
Aims: To assess the relationship between maternal clinical chorioamnionitis and neonatal outcome in preterm very-low birthweight (VLBW) infants. Methods: An observational case-control study was conducted in the Neonatology ...
El fill de mare diabètica: un experiment de la Natura
Del fill de mare diabètica (FMD) s´ha dit que es tracta d'un autèntic 'experiment de la natura' per tractar-se d'un ésser que al llarg dels seus creixement i desenvolupament intrauterins es relaciona amb un medi ambient ...
Liposomal iron in moderate chronic kidney disease
Introduction and objective: The optimal iron supplementation route of administration (intravenous vs. oral) in patients with chronic kidney disease (CKD) not on dialysis is a hot topic of debate. An oral preparation ...
Genetic predisposition to chronic lymphocytic leukemia is mediated by a BMF super-enhancer polymorphism
Chronic lymphocytic leukemia (CLL) is an adult B cell malignancy. Genome-wide association studies show that variation at 15q15.1 influences CLL risk. We deciphered the causal variant at 15q15.1 and the mechanism by which ...
Halo sign in fetal cytomegalovirus infection: cerebral imaging abnormalities and postmortem histopathology in cohort of 35 infected fetuses.
To evaluate the correlation of periventricular echogenic halo (halo sign) with histopathological findings and its association with other brain imaging abnormalities in fetuses with cytomegalovirus (CMV) infection.
Spread of ST348 Klebsiella pneumoniae producing NDM-1 in a peruvian hospital
The aim of this study was to characterize carbapenem-resistant Klebsiella pneumoniae (CR-Kp) isolates recovered from adults and children with severe bacteremia in a Peruvian Hospital in June 2018. Antimicrobial susceptibility ...
In vitro activity of 12 antimicrobial peptides against Mycobacterium tuberculosis and Mycobacterium avium clinical isolates
Tuberculosis (TB) remains a major threat to human health worldwide. The increasing incidence of non-tuberculous mycobacterial infections and particularly those produced by ...
Telemática y Pediatría
Se define como telemática aquel apartado de la Ciencia que estudia la comunicación en su versión más amplia. La expansión de sus aplicaciones es progresiva, de forma exponencial, y la razón fundamental de dicho fenómeno ...
Device for negative pressure wound therapy in low-resource regions: open-source description and bench test evaluation
Background: Negative (vacuum) pressure therapy promotes wound healing. However, commercially available devices are unaffordable to most potential users in low- and middle-income countries (LMICs), limiting access to many ...
Antimicrobial resistance and virulence characterisation among Escherichia coli clinical isolates causing severe obstetric infections in pregnant women
The virulence markers and the antimicrobial resistance profile of 78 Escherichia coli isolates causing obstetric infections accompanied or not by sepsis were studied. Adhesion-related virulence factors were the most ...
Resistències als principals fàrmacs antituberculosos, importància, detecció i alteracions genètiques associades.
Anualment es declaren de vuit a nou milions de casos de tuberculosi al món, amb gairebé dos milions de morts. El 10% dels casos són resistents a algun dels fàrmacs. Diferents factors influeixen en les resistències, com el ...
Validating a common tick survey method: cloth-dragging and line transects
Cloth-dragging is the most widely-used method for collecting and counting ticks, but there are few studies of its reliability. By using cloth-dragging, we applied a replicated line transects survey method, in two areas in ...
Mastopatía fibroquística
La malaltia fibroquística de la mamella o mastopatia fibroquística és un terme vague que pretén definir clínicament una síndrome constituïda per una nodularitat mamària palpable poc delimitada, d'extensió diversa, freqüentment ...
Predictive model for atrial fibrillation in hypertensive diabetic patients
Background: Several scores to identify patients at high risk of suffering atrial fibrillation have been developed. Their applicability in hypertensive diabetic patients, however, remains uncertain. Our aim is to develop ...
Perception and knowledge of the effect of climate change on infectious diseases within the general public: A multinational cross-sectional survey-based study
Infectious diseases are emerging and re-emerging due to climate change. Understanding how climate variability affects the transmission of infectious diseases is important for both researchers and the general public. Yet, ...
Quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal.
BACKGROUND: The aim of this study was to analyse the reasons for not starting or for early of radiotherapy at the Radiation Oncology Department. METHODS: All radiotherapy treatments from March 2010 to February 2012 were ...
Mutational Status of SMAD4 and FBXW7 Affects Clinical Outcome in TP53-Mutated Metastatic Colorectal Cancer
Next-generation sequencing (NGS) provides a molecular rationale to inform prognostic stratification and to guide personalized treatment in cancer patients. Here, we determined the prognostic and predictive value of actionable ...
Contribution of femoral and proximal sciatic nerve branches to the sensory innervation of hindlimb digits in the rat
The present study was performed to investigate the possibility of 'aberrant' innervation of the tips of the hindlimb digits in the rat, i.e., from other sources than the femoral and the main sciatic branches (tibial, ...
