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Fonaments Clínics: Recent submissions

Now showing items 321-340 of 627

    VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placenta. 

    Rovira Vallbona, Eduard; Monteiro, Isadora; Bardají, Azucena; Serra-Casas, Elisa; Neafsey, Daniel E.; Quelhas, Diana; Valim, Clarissa; Alonso, Pedro; Dobaño, Carlota, 1969-; Ordi i Majà, Jaume; Menéndez, Clara; Mayor Aparicio, Alfredo Gabriel (Publication date: 2018-09-19)

    Plasmodium falciparum infected erythrocytes (IE) accumulate in the placenta through the interaction between Duffy-binding like (DBL) domains of parasite-encoded ligand VAR2CSA and chondroitin sulphate-A (CSA) receptor. ...

    Spleen rupture in a case of untreated Plasmodium vivax infection 

    Machado Siqueira, André; Lopes Magalhães, Belisa Maria; Cardoso de Melo, Gisely; Ferrer, Mireia; Castillo, Paola; Martín Jaular, Lorena; Fernández Becerra, Carmen; Ordi i Majà, Jaume; Martínez, Antonio; Guimarães Lacerda, Marcus Vinícius; Portillo Obando, Hernando A. del (Publication date: 2021-03-16)

    We report the unique case of a 19-yearold nonimmune patient with Plasmodium vivax monoinfection, confirmed by PCR in the peripheral blood and in the spleen section, who was splenectomized due to spleen rupture two days ...

    Oleoyl Coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in Mycobacteria 

    Turapov, Obolbek; Waddell, Simon J.; Burke, Bernard; Glenn, Sarah; Sarybaeva, Asel A.; Tudó i Vilanova, Griselda; Labesse, Gilles; Young, Danielle I.; Young, Michael; Andrew, Peter W.; Butcher, Philip D.; Cohen Gonsaun, Martin; Mukamolova, Galina (Publication date: 2015-01-29)

    We have recently shown that RaaS (regulator of antimicrobial-assisted survival), encoded by Rv1219c in Mycobacterium tuberculosis and by bcg_1279c in Mycobacterium bovis bacillus Calmette-Guérin, plays an important role ...

    Alimentación parenteral total 

    Catalán, M.I.; Rodríguez Miguélez, M.; Pastor Durán, Xavier; Palomeque, A. (Publication date: 2014-11-12)

    El intenés médico por alimentar a los humanos por vías distintas a la oral es conocido desde el siglo XVII, pero sólo desde hace unos 20 aftos se puede realizar de una manera segura, prolongada y con posibilidades de éxito. ...

    Actualización de las recomendaciones para la determinación de biomarcadores en el carcinoma de pulmón avanzado de célula no pequeña. Consenso Nacional de la Sociedad Española de Anatomía Patológica y de la Sociedad Española de Oncología Médica 

    López Ríos, Fernando; Castro, Javier de; Concha, Ángel; Garrido, Pilar; Gómez Román, Javier; Isla, Dolores; Ramírez Ruz, J. (José); Paz-Ares, Luis; Sanz, Julián; Felip, Enriqueta (Publication date: 2017-12-15)

    En el año 2011 se inició un proyecto conjunto entre la Sociedad Española de Oncología Médica (SEOM) y la Sociedad Española de Anatomía Patológica (SEAP) para establecer unas recomendaciones basadas en la evidencia actual ...

    Prosthetic joint infection by Bordetella holmesii: Case report and a review of the literature 

    Fernández Pittol, Mariana José; Bosch Mestres, Jordi; Morata, Laura; Lozano, Luis; Martínez Pastor, Juan Carlos; Soriano Viladomiu, Alex (Publication date: 2020-05-11)

    Introduction: Bordetella holmesii is a Gram-negative coccobacillus involved in different infections mostly described in case reports. Prosthetic joint infections in relation to this pathogen are rare. Here, we present the ...

    First insights into the pleiotropic role of vrf (yedF), a newly characterized gene of Salmonella Typhimurium 

    Ballesté Delpierre, Clara Celia; Fernández Orth, Dietmar; Ferrer Navarro, Mario; Díaz Peña, Ramón; Odena Caballol, Antonia; Oliveira, Eliandre; Fàbrega Santamaria, Anna; Vila Estapé, Jordi (Publication date: 2017-12-11)

    Salmonella possesses virulence determinants that allow replication under extreme conditions and invasion of host cells, causing disease. Here, we examined four putative genes predicted ...

    Modelo 3D virtual de la columna vertebral lumbar 

    Prats Galino, Alberto; Reina, Miguel Angel; Mavar Haramija, Marija; Puigdellívol Sánchez, Anna; San Molina, Joan; Andrés, José Antonio de (Publication date: 2014-06-25)

    El modelo interactivo ha sido desarrollado a partir de reconstrucciones tridimensionales de imágenes de resonáncia magnética (RM).

    ¿Sepsis en LES?. Anticoagulante lúpico. Cuatro casos clínicos pediátricos 

    Roldán, A. (Aurora); Pastor Durán, Xavier; Palomeque, A.; Moreno Caballud, Ana; Quiñones, E. (Publication date: 2014-11-14)

    En el lupus eritematoso diseminado no son infrecuentes los trastornos de la coagulación, con hemorragias, que incluso en ocasiones pueden ser la primera manifestación; si además se añade fiebre puede malinterpretarse como ...

    Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers 

    Agirre, Xabier; Castellano, Giancarlo; Pascual, Marien; Heath, Simon C.; Kulis, Marta; Segura, Victor; Bergmann, Anke; Esteve Codina, Anna; Merkel, Angelika; Raineri, Emanuele; Agueda Calpena, Lídia; Blanc, Julie; Richardson, David; Clarke, Laura; Datta, Avik; Russiñol, Nuria; Queirós, Ana C.; Beekman, Renée; Rodríguez Madoz, Juan R.; San José-Eneriz, Edurne; Fang, Fang; Gutiérrez, Norma C.; García Verdugo, José M.; Robson, Michael I.; Schirmer, Eric C.; Guruceaga, Elisabeth; Martens, Joost H. A.; Gut, Marta; Calasanz, María José; Flicek, Paul; Siebert, Reiner; Campo Güerri, Elias; San Miguel, Jesús F.; Melnick, Ari; Stunnenberg, Hendrik G.; Gut, Ivo G.; Prosper, Felipe; Martín-Subero, José Ignacio (Publication date: 2016-11-08)

    While analyzing the DNA methylome of multiple myeloma (MM), a plasma cell neoplasm, by whole-genome bisulfite sequencing and high-density arrays, we observed a highly heterogeneous pattern globally characterized by regional ...

    Systematic review of the empirical evidence of study publication bias and outcome reporting bias 

    Dwan, Kerry; Altman, Douglas G.; Arnaiz Gargallo, Juan Alberto; Bloom, Jill; Chan, An-Wen; Cronin, Eugenia; Decullier, Evelyne; Easterbrook, Philippa; Elm, Erik Von; Gamble, Carrol; Ghersi, Davina; Ioannidis, John P. A.; Simes, John; Williamson, Paula R. (Publication date: 2018-09-25)

    Background The increased use of meta-analysis in systematic reviews of healthcare interventions has highlighted several types of bias that can arise during the completion of a randomised controlled trial. Study publication ...

    Enterococcus faecalis inhibits Klebsiella pneumoniae growth in polymicrobial biofilms in a glucose-enriched medium 

    Ballén, Victoria; Ratia, Carlos; Cepas, Virginio; Soto González, Sara M. (Publication date: 2022-03-01)

    Catheter-related urinary tract infections are one of the most common biofilm-associated diseases. Within biofilms, bacteria cooperate, compete, or have neutral interactions. This study aimed to investigate the interactions ...

    Trends in survival among extremely-low-birth-weight infants (less than 1000 g)without significant bronchopulmonary dysplasia 

    Botet Mussons, Francisco; Figueras Aloy, José, 1950-; Miracle Echegoyen, Xavier; Rodríguez Miguélez, José-Manuel; Salvia-Roiges, Ma Dolors; Carbonell i Estrany, Xavier (Publication date: 2015-01-09)

    Objective The aim of this study was to analyze the evolution from 1997 to 2009 of survival without significant (moderate and severe) bronchopulmonary dysplasia (SWsBPD) in extremely-low-birth-weight (ELBW) infants and to ...

    Resuscitating the Dying Autopsy 

    Bassat Orellana, Quique; Castillo, Paola; Alonso, Pedro; Ordi i Majà, Jaume; Menéndez, Clara (Publication date: 2016-03-30)

    Summary points Despite the relevant information that postmortem examinations can provide, autopsy rates have been declining worldwide in the last few decades. Autopsies are especially necessary in low-income countries, ...

    A novel NONO nonsense variant in a fetus with renal abnormalities 

    Rodríguez Revenga, Laia; Nadal Serra, Alfons; Borobio, Virginia; Álvarez Mora, María Isabel; Madrigal Bajo, Irene; Pauta, Montse; Borrell, Antoni (Publication date: 2024-12-04)

    At 16 + 6-weeks a fetal scan performed in the second pregnancy of a 42 y.o. woman identified a right multicystic dysplastic kidney, left renal agenesis, absent urinary bladder, myocardial hypertrophy, increased nuchal fold, ...

    MiR-SNPs as markers of toxicity and clinical outcome in Hodgkin Lymphoma patients 

    Navarro Ponz, Alfons; Muñoz, Carmen; Gaya, Anna; Díaz Beyà, Marina; Gel Moreno, Bernat; Tejero Villalba, Rut; Díaz Sánchez, Tania; Martínez Pozo, Antonio; Monzó Planella, Mariano (Publication date: 2014-03-24)

    Background: In recent years, microRNA (miRNA) pathways have emerged as a crucial system for the regulation of tumorogenesis. miR-SNPs are a novel class of single nucleotide polymorphisms that can affect miRNA pathways. ...

    Pulmonary alveolar proteinosis in two siblings 

    Palomeque, A.; Cruz Martínez, Ofelia; Ramírez Ruz, J. (José); Lambruschini, N.; Pastor Durán, Xavier; Jiménez González, Rafael; Cruz Hernández, Manuel (Publication date: 2015-09-28)

    Ocurrence of Pulmonary Alveolar Proteinosis (PAP) is reported in two siblings. The patients were both females diagnosed at 13 months and 1 month. Gastrointestinal symptoms with vomiting and failure to trhive started in the ...

    DWI and complex brain network analysis predicts vascular cognitive impairment in spontaneous hypertensive rats undergoing executive function tests 

    López Gil, Xavier; Amat Roldán, Iván; Tudela Fernández, Raúl; Castañé, Anna; Prats Galino, Alberto; Planas Obradors, Anna Maria; Farr, Tracy D.; Soria, Guadalupe (Publication date: 2015-04-24)

    The identification of biomarkers of vascular cognitive impairment is urgent for its early diagnosis. The aim of this study was to detect and monitor changes in brain structure and connectivity, and to correlate them with ...

    Usefulness of multidetector computed tomography to differentiate between renal cell carcinoma and oncocytoma. A model validation 

    Paño, Blanca; Soler, Alexandre; Goldman, Debra A.; Salvador, Rafael; Buñesch, Laura; Sebastià Cerqueda, Carmen; Nicolau, Carlos (Publication date: 2021-09-15)

    OBJECTIVE: The purpose of this study is to validate a multivariable predictive model previously developed to differentiate between renal cell carcinoma (RCC) and oncocytoma using CT parameters. METHODS AND MATERIALS: We ...

    Combating virulence of Gramnegative bacilli by OmpA inhibition 

    Vila Farrés, Xavier; Parra Millán, Raquel; Sánchez Encinales, Viviana; Varese, Monica; Ayerbe Algaba, Rafael; Bayó Puxan, Núria; Guardiola Bagán, Salvador; Pachón Ibáñez, María Eugenia; Kotev, Martin; García Arroyo, Jesús; Teixidó Turà, Meritxell; Vila Estapé, Jordi; Pachón, Jerónimo; Giralt Lledó, Ernest; Smani, Younes (Publication date: 2018-05-16)

    Preventing the adhesion of pathogens to host cells provides an innovative approach to tackling multidrug-resistant bacteria. In this regard, the identification of outer membrane protein A (OmpA) as a key bacterial virulence ...