Emotional intelligence and neurocognition profiles in first-episode psychosis: A two-year follow-up study 

Clougher, Derek; Forte, Maria Florencia; Mezquida Mateos, Gisela; Sánchez Torres, Ana M.; Serra Navarro, Maria; Penadés Rubio, Rafael; Lobo, Antonio; González-Pinto, Ana; Panadero Gómez, Rocío; Roldán, Alexandra; Vieta i Pascual, Eduard, 1963-; Serna, Elena de la, 1978-; Trabsa, Amira; Martínez-Arán, Anabel, 1971-; Torrent Font, Carla; Tortorella, Alfonso; Menculini, Giulia; Ramos-Quiroga, Josep Antoni; Cuesta, Manuel J.; Bernardo Arroyo, Miquel; Amoretti Guadall, Silvia; PEPs Group (Publication date: 2025-10-09)

Emotional intelligence (EI) and neurocognition (NC) impairments are common in first-episode psychosis (FEP), yet their evolution over time remains unclear. This study identified patient profiles in EI and NC performance ...

Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia 

Gimenez, Neus; Tripathi, Rupal; Giró, Ariadna; Rosich, Laia; López Guerra, Mónica; López Oreja, Irene; Playa-Albinyana, Heribert; Arenas Ríos, Fabián; Mas, José Manuel; Pérez Galán, Patricia; Delgado, Julio (Delgado González); Campo Güerri, Elias; Farrés, Judith; Colomer Pujol, Dolors (Publication date: 2025-10-23)

Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. Despite new targeted therapies such as ibrutinib and venetoclax, disease progression and relapse remain an issue. CLL ...

Challenges with Approved Targeted Therapies against Recurrent Mutations in CLL: A Place for New Actionable Targets 

López Oreja, Irene; Playa-Albinyana, Heribert; Arenas Ríos, Fabián; López Guerra, Mónica; Colomer Pujol, Dolors (Publication date: 2025-09-26)

Chronic lymphocytic leukemia (CLL) is characterized by a high degree of genetic variability and interpatient heterogeneity. In the last decade, novel alterations have been described. Some of them impact on the prognosis ...

SF3B1 mutation-mediated sensitization to H3B-8800 splicing inhibitor in chronic lymphocytic leukemia 

López Oreja, Irene; Gohr, Andre; Playa-Albinyana, Heribert; Giró, Ariadna; Arenas Ríos, Fabián; Higashi, Morihiro; Tripathi, Rupal; López Guerra, Mónica; Irimia Martínez, Manuel; Aymerich Gregorio, Marta; Valcárcel Juárez, Juan; Bonnal, Sophie; Colomer Pujol, Dolors (Publication date: 2025-11-12)

Splicing factor 3B subunit 1 (SF3B1) is involved in pre-mRNA branch site recognition and is the target of antitumor-splicing inhibitors. Mutations in SF3B1 are observed in 15% of patients with chronic lymphocytic leukemia ...

Imaging Efficacy of [18F]CTT1057 PET/CT in Patients with Biochemically Recurrent Prostate Cancer: Results from GuidePath-A Phase 3, Prospective Multicenter Study 

Fanti, Stefano; Robles Barba, Javier Jesus; Behr, Spencer; Maurer, Tobias; Paredes Barranco, Pilar; Walz, Jochen; Duch, Joan; Simo Perdigo, Marc; Mainta, Ismini Charis; Bonnefoy, Pierre Benoit; Coulanges, Medge; Tang, Jun; Seigne, Christelle; Wilke, Celine; Catafau, Ana M.; Iagaru, Andrei; Aggarwal, Rahul (Publication date: 2025-09-25)

Improved diagnostic accuracy in patients with prostate cancer at first biochemical recurrence (BCR) with low prostate-specific antigen (PSA) levels is needed. This prospective study (GuidePath; NCT04838613) aimed to evaluate ...

A low total metabolic tumor volume independently predicts for a longer time to first treatment in initially observed, low tumor burden follicular lymphoma 

Mozas, Pablo; Casanueva Eliceiry, Sebastián; Rivero, Andrea; Serna, Ángel; Simó, Marc; Rodríguez, Sonia; Rivas Delgado, Alfredo; Nadeu, Ferran; Correa, Juan Gonzalo; Piñeyroa, Juan Antonio; Pérez-Valencia, Amanda Isabel; Guinetti-Ortiz, Katia; Gómez-Hernando, Marta; Giné, Eva; Delgado, Julio; Villamor i Casas, Neus; Campo, Elías; Magnano, Laura; Abrisqueta Costa, Pau; Setoain Perego, Xavier; López-Guillermo, Aramando (Publication date: 2025-01-23)

Watchful waiting is an acceptable management strategy for advanced-stage, low tumor burden (LTB) patients with follicular lymphoma (FL). However, the prediction of how long this treatment-free observation period will last ...

Diagnóstico prequirúrgico de gliomas difusos en adultos: perspectivas prácticas de radiólogos de Unidades de neurooncología Post-WHO 2021 

Pons Escoda, Albert; Majós Torró, Carlos; Smits, Marion; Oleaga Zufiría, Laura (Publication date: 2024-08-30)

La Clasificación 2021 de tumores del sistema nervioso central (SNC) por la Organización Mundial de la Salud (OMS) fue acogida con entusiasmo, aunque al principio pudo parecer abrumadora. Con el tiempo, hemos comprendido ...

Dissemination of NDM-producing Klebsiella pneumoniae and Escherichia coli high-risk clones in Catalan healthcare institutions 

Marí Almirall, Marta; Cosgaya Castro, Clara; Pitart, Cristina; Viñes, Joaquim; Muñoz López, Laura; Campo, Irene; Cuscó, Anna; Rodríguez Serna, Laura; Santana, Gemina; Río, Ana del; Francino, Olga; Ciruela, Pilar; Pujol, Isabel; Ballester, Frederic; Marco, Francesc; Martínez Hernández, José Alfredo; Soriano Viladomiu, Alex; Vila Estapé, Jordi; Roca Subirà, Ignasi; MERCyCAT Study Group (Publication date: 2023-12-11)

Objectives: To characterize the clonal spread of carbapenem-resistant Klebsiella pneumoniae and Escherichia coli isolates between different healthcare institutions in Catalonia, Spain. Methods: Antimicrobial susceptibility ...

Halo sign in fetal cytomegalovirus infection: cerebral imaging abnormalities and postmortem histopathology in cohort of 35 infected fetuses. 

Hawkins-Villarreal, Ameth; Castillo, Karen; Nadal Serra, Alfons; Planas i Marcé, Sílvia, 1965-; Moreno Espinosa, Ana L.; Alarcón, Ana; Rebollo Polo, Mónica; Figueras Retuerta, Francesc; Gratacós Solsona, Eduard; Eixarch Roca, Elisenda; Goncé Mellgren, Anna (Publication date: 2024-02-05)

To evaluate the correlation of periventricular echogenic halo (halo sign) with histopathological findings and its association with other brain imaging abnormalities in fetuses with cytomegalovirus (CMV) infection.

Genotypic and phenotypic study of antiviral resistance mutations in refractory cytomegalovirus infection 

Santos Bravo, Marta; Nicolas Plault; Sánchez Palomino, Sonsoles; Rodríguez, Cristina; Navarro Gabriel, Mireia; Mosquera, María Mar; Fernández Avilés, Francesc; Suarez Lledó, María; Rovira, Montserrat; Bodro, Marta; Moreno Camacho, Ma. Asunción; Linares, Laura; Cofán Pujol, Federico; Berengua, Carla; Esteva, Cristina; Cordero, Elisa; Martín Dávila, Pilar; Aranzamendi, Maitane; Pérez Jiménez, Ana Belén; Vidal, Elisa; Fernández Sabé, Núria; Len, Óscar; Hantz, Sebastien; Alain, Sophie; Marcos, Ma. Angeles; the Spanish Network for Research in Infectious Diseases (REIPI); Group for the Study of Infection in Transplantation (GESITRA) (Publication date: 2023-12-04)

Background This study describes the genotypic and phenotypic characterization of novel human cytomegalovirus (HCMV) genetic variants of a cohort of 94 clinically resistant HCMV patients. Methods and results ...

Clinical and brain volumetric correlates of decreased DTI-ALPS, suggestive of local glymphatic dysfunction, in iRBD 

Roura, Ignacio; Pardo, Jèssica; Martín Barceló, Cristina; Falcón Falcón, Carles Maria; Oltra González, Javier; Campabadal Delgado, Anna; Bargalló Alabart, Núria; Serradell, Mónica; Mayà Casalprim, Gerard; Montini, Angelica; Pont Sunyer. Claustre; Gaig Ventura, Carles; Buongiorno, Maria Teresa; Junqué i Plaja, Carme, 1955-; Iranzo, Alex; Segura i Fàbregas, Bàrbara (Publication date: 2026-02-16)

Glymphatic alterations may underlie neurodegeneration in alpha-synucleinopathies. Reduced Diffusion-Tensor Imaging ALong the Perivascular Space (DTI-ALPS), a proxy of perivascular glymphatic activity, has been scarcely ...

Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study 

Spitzer, Hannah; Ripart, Mathilde; Whitaker, Kirstie; D'Arco, Felice; Mankad, Kshitij; Chen, Andrew A.; Napolitano, Antonio; De Palma, Luca; De Benedictis, Alessandro; Foldes, Stephen; Humphreys, Zachary; Zhang, Kai; Hu, Wenhan; Mo, Jiajie; Likeman, Marcus; Davies, Shirin; Güttler, Christopher; Lenge, Matteo; Cohen, Nathan T.; Tang, Yingying; Wang, Shan; Chari, Aswin; Tisdall, Martin; Bargalló Alabart, Núria; Conde Blanco, Estefanía; Pariente, Jose Carlos; Pascual-Diaz, Saül; Delgado-Martínez, Ignacio; Pérez-Enríquez, Carmen; Lagorio, Ilaria; Abela, Eugenio; Mullatti, Nandini; O'Muircheartaigh, Jonathan; Vecchiato, Katy; Liu, Yawu; Caligiuri, Maria Eugenia; Sinclair, Ben; Vivash, Lucy; Willard, Anna; Kandasamy, Jothy; McLellan, Ailsa; Sokol, Drahoslav; Semmelroch, Mira; Kloster AG; Opheim, Giske; Ribeiro, Letícia; Yasuda, Clarissa; Rossi-Espagnet, Camilla; Hamandi, Khalid; Tietze, Anna; Barba, Carmen; Guerrini, Renzo; Gaillard, William Davis; You, Xiaozhen; Wang, Irene; González Ortiz, Sofía; Severino, Mariasavina; Striano, Pasquale; Tortora, Domenico; Kälviäinen, Reetta; Gambardella, Antonio; Labate, Angelo; Desmond, Patricia; Lui. Elaine; O'Brien, Terence; Shetty, Jay; Jackson, Graeme; Duncan, John S.; Winston, Gavin P.; Pinborg, Lars H.; Cendes, Fernando; Theis, Fabian J.; Shinohara, Russell T.; Cross, Judith Helen; Baldeweg, Torsten; Adler, Sophie; Wagstyl, Konrad (Publication date: 2026-01-27)

One outstanding challenge for machine learning in diagnostic biomedical imaging is algorithm interpretability. A key application is the identification of subtle epileptogenic focal cortical dysplasias (FCDs) from structural ...

Ultrasensitive multiplex optical quantification of bacteria in large samples of biofluids 

Pazos Pérez, Nicolas; Pazos, Elena; Catala, Carme; Mir Simon, Bernat; Gómez de Pedro, Sara; Sagales, Juan; Villanueva, Carlos; Vila Estapé, Jordi; Soriano Viladomiu, Alex; García de Abajo, F. Javier; Álvarez Puebla, Ramón A. (Publication date: 2016-09-06)

Efficient treatments in bacterial infections require the fast and accurate recognition of pathogens, with concentrations as low as one per milliliter in the case of septicemia. Detecting ...

The many faces of small B cell lymphomas with plasmacytic differentiation and the contribution of MYD88 testing 

Swerdlow, Steven H.; Kuzu, Isinsu; Dogan, Ahmet; Dirnhofer, Stephan; Chan, John K. C.; Sander, Birgitta; Ott, German; Xerri, Luc; Quintanilla Martinez, Leticia; Campo Güerri, Elias (Publication date: 2019-02-11)

Plasmacytic differentiation may occur in almost all small B cell lymphomas (SBLs), although it varies from being uniformly present (as in lymphoplasmacytic lymphoma (LPL)) to very uncommon (as in mantle cell lymphomas ...

L'Intrusisme professional a principis del segle XX. El Dr. James M. Munyon. 

Torres, Begoña; Sabaté i Casellas, Ferran (Publication date: 2015-01-28)

RESUM: Presentem al Dr. James M. Munyon, qui a principis del segle passat es dedicà a la manufactura i patent de remeis homeopàtics. Va ser perseguit per frau en múltiples ocasions però la seva gran fortuna li va permetre ...

Perivascular epitheliod cell tumors: Study of three gynecological cases 

Nicolás, Inmaculada; Fusté, Pere; Saco, Adela; Ordi i Majà, Jaume; Torné Bladé, Aureli (Publication date: 2021-06-25)

Antecedents: Perivascular epitheliod cell tumor (PEComa) is a rare mesenchymal tumor. They are rare in the field of gynecology, which makes them difficult to consider as a possible diagnostic. We aim to contribute with our ...

Biofilm Formation in Uropathogenic Escherichia coli Strains: Relationship with Urovirulence Factors and Antimicrobial Resistance 

Soto González, Sara M.; Marco, Francesc; Guiral Vilalta, Elisabet; Vila Estapé, Jordi (Publication date: 2021-03-05)

Evidence of activation of the Toll-like receptor-4 proinflammatory pathway in patients with schizophrenia 

García Bueno, Borja; Gassó Astorga, Patricia; MacDowell, Karina S.; Callado, Luis F.; Mas Herrero, Sergi; Bernardo Arroyo, Miquel; Lafuente, Amàlia, 1952-2022; Meana, J. Javier; Leza, Juan Carlos (Publication date: 2018-01-12)

BACKGROUND: Alterations in the innate immune/inflammatory system may underlie the pathophysiology of schizophrenia, but we do not understand the mechanisms involved. The main agents of innate immunity are the Toll-like ...

Genotypic and phenotypic study of antiviral resistance mutations in refractory cytomegalovirus infection 

Santos Bravo, Marta; Nicolas Plault; Sánchez-Palomino, Sonsoles; Rodríguez, Cristina; Navarro Gabriel, Mireia; Mosquera, María Mar; Fernández Avilés, Francesc; Suárez-Lledó Grande, María; Rovira, Montserrat; Bodro, Marta; Moreno Camacho, Ma. Asunción; Linares, Laura; Cofán Pujol, Federico; Berengua, Carla; Esteva, Cristina; Cordero, Elisa; Martín Dávila, Pilar; Aranzamendi, Maitane; Pérez Jiménez, Ana Belén; Vidal, Elisa; Fernández Sabé, Núria; Len, Óscar; Hantz, Sebastien; Alain, Sophie; Marcos, Ma. Angeles; Spanish Network for Research in Infectious Diseases (REIPI); Group for the Study of Infection in Transplantation (GESITRA) (Publication date: 2023-12-05)

Background This study describes the genotypic and phenotypic characterization of novel human cytomegalovirus (HCMV) genetic variants of a cohort of 94 clinically resistant HCMV patients. Methods and results ...

Impact of Region-of-Interest Delineation Methods, Reconstruction Algorithms, and Intra- and Inter-Operator Variability on Internal Dosimetry Estimates Using PET 

López Vilanova, N.; Pavía Segura, Javier; Duch Guillén, Ma. Amor (María Amor); Catafau Alcántara, Ana Ma.; Ros Puig, Domènec; Bullich Roig, Santiago (Publication date: 2019-02-05)

Purpose: Human dosimetry studies play a central role in radioligand development for positron emission tomography (PET). Drawing regions of interest (ROIs) on the PET images is used to measure the dose in each organ. In the ...