miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice 

Clapé, Cyrielle; Fritz, Vanessa; Henriquet, Corinne; Apparailly, Florence; Fernández Ruiz, Pedro Luis; Iborra, François; Avancès, Christophe; Villalba, Martin; Culine, Stéphane; Fajas, Lluis (Data de publicació: 2013-06-06)

Abstract Background: Micro RNAs are small, non-coding, single-stranded RNAs that negatively regulate gene expression at the post-transcriptional level. Since miR-143 was found to be down-regulated in prostate cancer cells, ...

Sistemas informatizados de historia clínica 

Pastor Durán, Xavier; Jaureguizar, J. (Data de publicació: 2014-12-02)

Cualquiera que pregunte a un médico qué desea de una historia clínica informatizada recibirá la misma respuesta:'poder obtener información actualizada y útil del paciente cuando quiera, dónde quiera y cómo quiera'. Para ...

The prognostic impact of minimal residual disease in patients with chronic lymphocytic leukemia requiring first-line therapy. 

Santacruz, Rodrigo; Villamor i Casas, Neus; Aymerich Gregorio, Marta; Martínez Trillos, Alejandra; López González, Cristina; Navarro López, Alba; Rozman, María; Beà Bobet, Sílvia M.; Royo Moreno, Cristina; Cazorla, Maite; Colomer Pujol, Dolors; Giné Soca, Eva; Pinyol, Magda; Puente, Xose S.; López-Otin, Carlos; Campo Güerri, Elias; López Guillermo, Armando; Delgado, Julio (Delgado González) (Data de publicació: 2018-03-27)

A proportion of patients with chronic lymphocytic leukemia achieve a minimal residual disease negative status after therapy. We retrospectively evaluated the impact of minimal residual disease on the outcome of 255 consecutive ...

Calodium hepaticum: Household Clustering Transmission and the Finding of a Source of Human Spurious Infection in a Community of the Amazon Region 

Queiroga Gonçalves, Alessandra; Ascaso Terrén, Carlos; Santos, Ivanildes; Serra Taquita, Paula; Julião Rebouça, Genimar; Orlandi, Patricia (Data de publicació: 2020-01-14)

Background: Calodium hepaticum (syn. Capillaria hepatica) is a worldwide helminth parasite of which several aspects of transmission still remain unclear. In the Amazon region, the mechanism of transmission based on the ...

A low total metabolic tumor volume independently predicts for a longer time to first treatment in initially observed, low tumor burden follicular lymphoma 

Mozas, Pablo; Casanueva Eliceiry, Sebastián; Rivero, Andrea; Serna, Ángel; Simó, Marc; Rodríguez, Sara; Rivas Delgado, Alfredo; Nadeu Prat, Ferran; Correa, Juan Gonzalo; Piñeyroa, Juan Antonio; Pérez Valencia, Amanda Isabel; Guinetti Ortiz, Katia; Gómez Hernando, Marta; Giné Soca, Eva; Delgado González, Julio; Villamor i Casas, Neus; Campo Güerri, Elias; Magnano, Laura; Abrisqueta Costa, Pau; Setoain Perego, Xavier; López Guillermo, Armando (Data de publicació: 2025-01-29)

Watchful waiting is an acceptable management strategy for advanced-stage, low tumor burden (LTB) patients with follicular lymphoma (FL). However, the prediction of how long this treatment-free observation period will last ...

Strategies to design new antibacterial drugs (Seminaris Tecnològics 2018) 

Vila Estapé, Jordi (Data de publicació: 2018-09-21)

Link between cognitive polygenic risk scores and clinical progression after a first-psychotic episode 

Gonzalez Segura, Àlex; Mezquida Mateos, Gisela; Martínez Pinteño, Albert; Gassó Astorga, Patricia; Rodríguez Ferret, Natalia; Moreno Izco, Lucía; Amoretti Guadall, Silvia; Bioque Alcázar, Miquel; Lobo, Antonio; González-Pinto, Ana; García-Alcon, Alicia; Roldán, Alexandra; Vieta i Pascual, Eduard, 1963-; Serna Gómez, Elena de la; Toll Privat, Alba; Cuesta, Manuel J.; Mas Herrero, Sergi; Bernardo Arroyo, Miquel; PEPs Group (Data de publicació: 2024-11-07)

Background: Clinical intervention in early stages of psychotic disorders is crucial for the prevention of severe symptomatology trajectories and poor outcomes. Genetic variability is studied as a promising modulator of ...

Intracoronary administration of allogeneic adipose tissue-derived mesenchymal stem cells improves myocardial perfusion but not left ventricle function, in a translational model of acute myocardial infarction 

Bobi, Joaquim; Solanes, Núria; Fernández Jiménez, Rodrigo; Galán Arriola, Carlos; Dantas, Ana Paula; Fernández Friera, Leticia; Gálvez Montón, Carolina; Rigol Monzó, Elisabet; Agüero, Jaume; Ramírez Ruz, J. (José); Roqué i Moreno, Mercè; Bayés Genís, Antoni; Sánchez González, Javier; García Álvarez, Ana; Sabaté Tenas, Manuel; Roura, Santiago; Ibáñez Cabeza, Borja; Rigol Muxart, Montserrat (Data de publicació: 2018-09-05)

Background-¿Autologous adipose tissue-derived mesenchymal stem cells (ATMSCs) therapy is a promising strategy to improve post-myocardial infarction outcomes. In a porcine model of acute myocardial infarction, we studied ...

Accuracy and reproducibility of lymphoscintigraphy for sentinel node detection in patients with cutaneous melanoma. 

Vidal, Mónica; Vidal i Sicart, Sergi; Torrents, Abiguei; Perissinotti, Andrés; Navales, Ignacio; Paredes Barranco, Pilar; Pons Pons, Francisca (Data de publicació: 2013-02-06)

Lymphoscintigraphy is an important part of the mapping and identification of sentinel lymph nodes (SLNs). However, few studies report its reproducibility, and some concerns prevail. The aim of the study was to determine ...

Characterization of Vaginal Escherichia coli Isolated from Pregnant Women in Two Different African Sites 

Sáez-López, Emma; Cossa, Anelsio; Benmessaoud, Rachid; Madrid, Lola; Moraleda Redecilla, Cinta; Villanueva, Sonia; Tligui, Houssain; Moiane, Benilde; Alami, Hassan; Massora, Sérgio; Bezad, Rachid; Mandomando, Inácio; Bosch Mestres, Jordi; Vila Estapé, Jordi; Bassat Orellana, Quique; Soto González, Sara M. (Data de publicació: 2016-09-05)

The relevance of vaginal colonization of pregnant women by Escherichia coli is poorly understood, despite these strains sharing a similar virulence profile with other extraintestinal ...

Identification of Methylated Genes Associated with Aggressive Clinicopathological Features in Mantle Cell Lymphoma 

Enjuanes, Anna; Fernàndez Pascual, Verònica; Hernández, Luis; Navarro, Alba; Beà Bobet, Sílvia M.; Pinyol, Magda; López Guillermo, Armando; Rosenwald, Andreas; Ott, German; Campo Güerri, Elias; Jares Gerboles, Pedro (Data de publicació: 2013-05-28)

Background: Mantle cell lymphoma (MCL) is genetically characterized by the t(11;14)(q13;q32) translocation and a high number of secondary chromosomal alterations. The contribution of DNA methylation to MCL lymphomagenesis ...

Acquisition of Pseudomonas aeruginosa and its resistance phenotypes in critically-ill medical patients: role of colonization pressure and antibiotic exposure 

Cobos-Trigueros, Nazaret; Solé, Mar; Castro Rebollo, Pedro; Torres, Jorge Luis; Hernández-Munain, Cristina; Rinaudo, Mariano; Fernández, Sara (Fernández García); Soriano Viladomiu, Alex; Nicolás Arfelis, Josep Maria; Mensa Pueyo, Josep; Vila Estapé, Jordi; Martínez, José Antonio (Martínez Martínez) (Data de publicació: 2016-11-09)

The objective of this work was to investigate the risk factors for the acquisition of Pseudomonas aeruginosa and its resistance phenotypes in critically ill patients, taking into account colonization pressure. METHODS: We ...

Síndrome de Reye. Diagnóstico precoz por biopsia muscular 

Palomeque, A.; Hostalot, A.; Jovani, L.; Pastor Durán, Xavier (Data de publicació: 2016-01-11)

Se presenta el caso de un síndrome de Reye en un lactante de dos meses, diagnosticado mediante biopsia muscular a lo dos día de iniciado el cuadro clínico. Se destaca el interés del estudio en músculo por la facilidad de ...

Alcoholic Foamy Degeneration, an Entity Resembling Alcohol-Associated Hepatitis: Diagnosis, Prognosis, and Molecular Profiling 

Gratacós-Ginès, Jordi; Avitabile, Emma; Montironi, Carla; Guillamon Thiery, Alex; Hernández Évole, Helena; Moreta, Maria José; Blaya, Delia; Ariño, Silvia; Rubio, A.B.; Pérez-Guasch, Martina; Cervera, Marta; Carol, Marta; Fabrellas i Padrès, Núria; Soria, Anna; Juanola, Adrià; Graupera, Isabel; Sancho-Bru, Pau; Díaz Lorca, Maria Alba; Coll, Mar; Bataller, R.; Ginès i Gibert, Pere; Pose Méndez, Elisa (Data de publicació: 2025-01-15)

Background & aims: Alcoholic foamy degeneration (AFD) is a condition with similar clinical presentation to alcohol-associated hepatitis (AH), but with a specific histologic pattern. Information regarding the prevalence and ...

Germ line variants in patients with acute myeloid leukemia without a suspicion of hereditary hematologic malignancy syndrome 

Guijarro Tomàs, Francisca; López-Guerra, Mónica; Morata, Jordi; Bataller Torralba, Alex; Paz Jené, Sara; Cornet Masana, Josep Maria; Banús Mulet, Antònia; Cuesta Casanovas, Laia; Carbó, José M.; Castaño Díez, Sandra; Jiménez Vicente, Carlos; Cortés Bullich, Albert; Triguero, Ana; Martínez Roca, Alexandra; Esteban, Daniel; Gómez Hernando, Marta; Álamo Moreno, José Ramón; López Oreja, Irene; Garrote i Ordeig, Marta; Risueño, Ruth M.; Tonda, Raúl; Gut, Ivo G.; Colomer Pujol, Dolors; Díaz Beyà, Marina; Esteve Reyner, Jordi (Data de publicació: 2025-03-26)

Germ line predisposition in acute myeloid leukemia (AML) has gained attention in recent years because of a nonnegligible frequency and an impact on management of patients and their relatives. Risk alleles for AML development ...

Congenital extrahepatic portosystemic shunts (Abernethy malformation): An international observational study 

Baiges Aznar, Anna; Turon, Fanny; Simón Talero, Macarena; Tasayco, Stephanie; Bueno, Javier; Zekrini, Kamal; Plessier, Aurélie; Franchi-Abella, Stéphanie; Guerin, Florent; Mukund, Amar; Eapen, C.E.; Goel, Ashish; Shyamkumar, Nidugala K.; Coenen, Sandra; Gottardi, Andrea de; Majumdar, Avik; Onali, Simona; Shukla, Akash; Carrilho, Flair José; Nacif, Lucas; Primignani, Massimo; Tosetti, Giulia; La Mura, Vincenzo; Nevens, Frederick; Witters, Peter; Tripathi, Dhiraj; Tellez, Luis; Martínez González, Javier; Álvarez-Navascués, Carmen; López Fraile López, Miguel; Procopet, Bogdan; Piscaglia, Fabio; Koning, Barbara de; Llop, Elba; Romero Cristobal, Mario; Tjwa, Eric; Monescillo, Alberto; Senzolo, Marco; Perez-LaFuente, Mercedes; Garcia Criado, María Ángeles; Segarra, Antonio; Kumar Sarin, Shiv; Hernández Gea, Virginia; Patch, David; Laleman, Wim; Hartog, Hermien; Valla, Dominique; Genescà, Joan; García Pagán, Juan Carlos (Data de publicació: 2020-05-15)

Congenital extrahepatic portosystemic shunt (CEPS) or Abernethy malformation is a rare condition in which splanchnic venous blood bypasses the liver draining directly into systemic circulation through a congenital shunt. ...

Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease 

Barreiro Capurro, Alicia; Mascaró Galy, José Manuel; Galindo, Beatriz Alejo; Giavedoni, Priscila; Carrera Álvarez, Cristina; Alós i Hernández, Llúcia; Puig i Sardà, Susana; Malvehy, J. (Josep) (Data de publicació: 2020-06-09)

Patients treated with haematopoietic stem cell transplantation are at increased risk of cutaneous malignant neoplasms. There are no reports on the characteristics of melanocytic lesions in patients with chronic graft versus ...

Malignant asbestos‐related disease in a population exposed to asbestos 

Orriols Martínez, Ramon; Tarrés Olivella, Josep; Alberti-Casas, Constança; Rosell-Murphy, Magdalena Isabel; Abós-Herràndiz, Rafael; Canela i Soler, Jaume (Data de publicació: 2020-07-09)

Abstract Objectives: The first asbestos fiber cement plant in Spain operated in Cerdanyola, in the Barcelona metropolitan area, between 1907 and 1997. We describe clinical and epidemiological characteristics of patients ...

Effects of a mutation in the gyrA gene on the virulence of uropathogenic Escherichia coli 

Sánchez Céspedes, Javier; Sáez-López, Emma; Frimodt-Mφller, N.; Soto González, Sara M.; Vila Estapé, Jordi (Data de publicació: 2016-06-16)

Fluoroquinolones are among the drugs most extensively used for the treatment of bacterial infections in human and veterinary medicine. Resistance to quinolones can be chromosome or plasmid mediated. The chromosomal mechanism ...

Clinical evolution of sacral stress fractures: influence of additional pelvic fractures 

Peris Bernal, Pilar; Guañabens Gay, Núria; Pons Pons, Francisca; Herranz, R.; Monegal Brancós, Ana; Suris, Xavier; Muñoz Gómez, José (Data de publicació: 2012-03-05)

To evaluate the clinical evolution of sacral stress fractures in relation to the scintigraphic pattern and the presence of additional pelvic fractures. METHODS--This was a retrospective study of 14 patients with sacral ...